To develop the next generation of musculoskeletal researchers, we believe it is important to be exposed to basic musculoskeletal biology all the way to clinical science. Through this exposure, one can appreciate the spectrum of research that is necessary for discoveries to progress from bench to bedside. Furthermore, understanding different research techniques used in the musculoskeletal field provides a basis to better grasp research projects that span the spectrum. The musculoskeletal science curriculum described below will provide training in these areas and will also provide formal education in grant writing. The trainees that are supported by the T32 Program will be required to prepare and submit a proposal for extramural funding (i.e., NIH F31/32) at the end of the first year or the beginning of the second year. The musculoskeletal science curriculum is divided into five lecture series that will run over a two-year period.