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Department of Orthopedics

School of Medicine

Welcome to Adams Lab

Lab Director, Douglas J. Adams, Ph.D.

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University Quick Links

    Publications

    Pubmed link: https://www.ncbi.nlm.nih.gov/myncbi/douglas.adams.1/bibliography/public/
    CU Profiles: https://profiles.ucdenver.edu/display/20414839

    Select publications:

    • Rowe DW, Hong SH, Zhang C, Shin DG, Adams DJ, Youngstrom DW, Chen L, Wu Z, Zhou Y, Maye P. Skeletal screening IMPC/KOMP using μCT and computer automated cryohistology: Application to the Efna4 KO mouse line. Bone. 2021 Mar;144:115688. doi: 10.1016/j.bone.2020.115688. Epub 2020 Oct 14. PubMed PMID: 33065355.
    • Novak S, Roeder E, Sinder BP, Adams DJ, Siebel CW, Grcevic D, Hankenson KD, Matthews BG, Kalajzic I. Modulation of Notch1 signaling regulates bone fracture healing. J Orthop Res. 2020 Nov;38(11):2350-2361. doi: 10.1002/jor.24650. Epub 2020 Mar 16. PubMed PMID: 32141629; PubMed Central PMCID: PMC7483882.
    • Shin B, Won H, Adams DJ, Lee SK. CD55 Regulates Bone Mass in Mice by Modulating RANKL-Mediated Rac Signaling and Osteoclast Function. J Bone Miner Res. 2020 Jan;35(1):130-142. doi: 10.1002/jbmr.3861. Epub 2019 Oct 23. PubMed PMID: 31487060.
    • Hagiwara Y, Dyrna F, Kuntz AF, Adams DJ, Dyment NA. Cells from a GDF5 origin produce zonal tendon-to-bone attachments following anterior cruciate ligament reconstruction. Ann N Y Acad Sci. 2020 Jan;1460(1):57-67. doi: 10.1111/nyas.14250. Epub 2019 Oct 9. PubMed PMID: 31596513; PubMed Central PMCID: PMC6992521.
    • Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai R, Vulpescu NA, Forgetta V, Kleinman A, Mohanty S, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon M-M, Pramatarova A,  Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum A-T, Mannan NS, Komla-Ebri D, Pollard AS, Dewhurst HF, Hassall T, Beltejar M-J G, 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani E, Evangelou E, Ohlsson C, Karasik D, Rivadeneira R, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu Y-H, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB:  An Atlas of Human and Murine Genetic Influences on Osteoporosis.  Nat Genet, 51(2):258-266, 2019.  PubMed PMID: 30598549.
    • Choudhary S, Santone E, Pok Y-S, Lorenzo JA, Adams DJ, Goetjen A, McCarthy MB, Mazzocca AD, Pilbeam C:  Continuous PTH in Male Mice Causes Bone Loss Because it Induces Serum Amyloid A (SAA), Endocrinology, 159(7):2759-2776, 2018.  PubMed PMID: 29757436
    • Rowe DW, Adams DJ, Hong S-H, Zhang C, Shin D-G, Rydzik R, Chen L, Wu Z, Zhang C, Garland G, Godfrey DA, Sundberg JP, Ackert-Bicknell CL:  Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by µCT and Histomorphometry.  Curr Osteo Rep, 16(2):77-94, 2018.  PMID: 29508144
    • Dyment NA, Jiang X, Chen L, Hong S-H, Adams DJ, Ackert-Bicknell CL, Shin D-G, Rowe DW: High-Throughput, Multi-Image Cryohistology of Mineralized Tissues, J Vis Exp, (115), e54468, doi:10.3791/54468, 2016.  PMID 27684089
    • Adams DJ, Rowe DW, Ackert-Bicknell CL:  Genetics of Aging Bone, Mamm Genome, 27(7):367-380, 2016.  PMID 27272104
    • Mori Y, Adams DJ, Hagiwara Y, Yoshida R, Kamimura M, Itoi E, Rowe DW: Identification of a progenitor cell population destined to form fracture fibrocartilage callus in Dickkopf-related protein 3-green fluorescent protein reporter mice.  J Bone Miner Metab, 34(6):606-614, 2016.  PMID 26369320
    • Tinsley BA, Dukas A, Pensak M, Adams DJ, Tang H, Ominsky MS, Ke HZ, Lieberman JR: Systemic Administration of Sclerostin Antibody Enhances BMP-Induced Bone Repair in a Rat Femoral Defect Model. J Bone Joint Surg, 97(22):1852-1859, 2015.  PMID 26582615
    • Adams DJ, Ackert-Bicknell CL:  Genetic regulation of bone strength: a review of animal model studies.  BoneKEy Reports 4, Article number: 714 (2015), doi:10.1038/bonekey.2015.83.  PMID 26157577
    • Hagiwara Y, Dyment NA, Jiang X, Huang JP, Ackert-Bicknell C, Adams DJ, Rowe DW:  Fixation Stability Dictates the Differentiation Pathway of Periosteal Progenitor Cells in Fracture Repair.  J Orthop Res, 33(7):948-956, 2015.  PMID 25639792
    • Dyment NA, Hagiwara Y, Jiang X, Huang JP, Adams DJ, Rowe DW:  Response of Knee Fibrocartilage to Joint Destabilization.  Osteoarth Cartil, 23(6):996-1006, 2015.  PMID 25680653
    • Matthews BG, Grcevic D, Wang L, Hagiwara Y, Rogulijic H, Joshi P, Shin D-G, Adams DJ, Kalajzic I: Analysis of aSMA-Labeled Progenitor Cell Commitment Identifies Notch Signaling as an Important Pathway in Fracture Healing.  J Bone Min Res, 29(5):1283-1294, 2014.  PMID 24190076
    • Ushiku C, Adams DJ, Jiang X, Wang L, Rowe DW:  Long Bone Fracture Repair in Mice Harboring GFP Reporters for Cells within the Osteoblastic Lineage.  J Orthop Res, 28(10):1338-1347, 2010.  PMID 20839319
    • Clinthorne JF, Adams DJ, Fenton JI, Ritz BW, Gardner EM: Short-Term Re-feeding of Previously Energy-Restricted C57/BL6 Male Mice Restores Body Weight and Body Fat and Attenuates the Decline in Natural Killer Cell Function after Primary Influenza Infection.  J Nutr, 140(8):1495-1501, 2010.  PMID 20534876
    • Freilich M, Shafer D, Wei M, Kompalli R, Adams D, Kuhn L:  Implant System for Guiding a New Layer of Bone: Computed Microtomography and Histomorphometric Analysis in the Rabbit Mandible.  Clin Oral Impl Res, 20(2):201-207, 2009.  PMID 19191797

    Orthopedics (SOM)

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