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Karin A. Payne, PhD

Karin A. Payne, PhD

Associate Professor of Orthopedics

Welcome to Payne Lab

Functional Regenerative Medicine

Our research focuses on the development of functional regenerative medicine approaches for bone and cartilage tissues, with a particular interest in treating  growth plate cartilage injuries affecting the pediatric population. We study this important clinical problem at a mechanistic level where we investigate the role of angiogenesis in bony repair tissue formation, which occurs after growth plate injury and is the central cause of associated growth abnormalities. At a translational level, we are evaluating different potential treatments by combining stem cells, biomaterials, and 3D printing. Other active projects in the laboratory are related to enhancing bone formation during spinal fusion, as well as developing regenerative medicine approaches for post-traumatic osteoarthritis.

 

 


LAB MEMBERS

OUR RESEARCH

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Growth Plate

Projects

Growth Plate

The growth plate (or physis) is a cartilage region at the end of all long bones in children that provides signals for bones to lengthen during development.

 

View All Projects

Publications

  1. Erickson CB, Newsom JP, Fletcher NA, Yu Y, Rodriguez-Fontan F, Weatherford SA, Miller NH, Krebs MD, Payne KA. Anti-VEGF Antibody Delivered Locally Reduces Bony Bar Formation Following Physeal Injury in Rats. J Orthop Res. 2020 Nov 12;. doi: 10.1002/jor.24907. [Epub ahead of print] PubMed PMID: 33179297.
  2. Erickson CB, Newsom JP, Fletcher NA, Feuer ZM, Yu Y, Rodriguez-Fontan F, Hadley Miller N, Krebs MD, Payne KA. In vivo degradation rate of alginate-chitosan hydrogels influences tissue repair following physeal injury. J Biomed Mater Res B Appl Biomater. 2020 Aug;108(6):2484-2494. doi: 10.1002/jbm.b.34580. Epub 2020 Feb 8. PubMed PMID: 32034881.
  3. Yu Y, Rodriguez-Fontan F, Eckstein K, Muralidharan A, Uzcategui AC, Fuchs JR, Weatherford S, Erickson CB, Bryant SJ, Ferguson VL, Hadley Miller N, Li G, Payne KA. Rabbit Model of Physeal Injury for the Evaluation of Regenerative Medicine Approaches. Tissue Eng Part C Methods. 2019 Dec;25(12):701-710. doi: 10.1089/ten.TEC.2019.0180. Epub 2019 Oct 31. PubMed PMID: 31552802; PubMed Central PMCID: PMC6919263.

View All Publications

Contact Us

Payne Lab

Mail Stop 8343
Research Complex 1 North
12800 E. 19th Avenue,
Room 2102
Aurora, CO 80045

Office: 303-724-0384

Karin.payne@cuanschutz.edu



Tweets by PayneOrthoLab Follow @payneortholab

Orthopedics (SOM)

CU Anschutz
Academic Office One

12631 East 17th Avenue

4602

Aurora, CO 80045

303-724-2955

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