Thomas Jansson, MD, PhD

Florence Crozier Cobb Endowed Professor
Chief, Division of Reproductive Sciences
Vice Chair of Research, Department of Obstetrics and Gynecology

Education
MD, Gothenburg University, Sweden (1985)
PhD in Physiology, Gothenburg University, Sweden (1990)

Contact
Research Complex 2
12700 East 19th Avenue
Room 3100C, MS 8613
Aurora, CO 80045

Phone: (303) 724-8622
Fax: (303) 724-3512

Research Interests
Dr. Jansson has national and international recognition for his translational research exploring the cellular and molecular mechanisms of regulation of placental nutrient transporters and investigating the role of placental function in determining fetal growth and long-term health. Dr. Jansson has a distinguished publication record, serves regularly on NIH and international study sections and is the Principal Investigator on numerous NIH grants.

Full List of Publications

Recent Publications

1. James-Allan LB, Rosario FJ, Barner K, Lai A, Guanzon D, McIntyre HD, Lappas M, Powell TL, Salomon C, Jansson T. Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes. FASEB J. 2020 Apr; 34(4):5724-5739. PMID: 32154621.
2. James-Allan LB, Teal S, Powell TL, Jansson T. Changes in Placental Nutrient Transporter Protein Expression and Activity Across Gestation in Normal and Obese Women. Reprod Sci. 2020 Feb 18. PMID: 32072607.
3. Stremming J, Jansson T, Powell TL, Rozance PJ, Brown LD. Reduced Na+ K+ -ATPase activity may reduce amino acid uptake in intrauterine growth restricted fetal sheep muscle despite unchanged ex vivo amino acid transporter activity. J Physiol. 2020 Apr; 598(8):1625-1639. PMID: 31909825.
4. Jansson T, Castillo-Castrejon M, Gupta MB, Powell TL, Rosario FJ. Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction. Clin Sci (Lond). 2020 Jan 17; 134(1):53-70. PMID: 31825077.
5. Vaughan OR, Thompson F, Lorca RA, Julian CG, Powell TL, Moore LG, Jansson T. Effect of high altitude on human placental amino acid transport. J Appl Physiol (1985). 2020 Jan 01; 128(1):127-133. PMID: 31804891.
6. Jessel RH, Rosario FJ, Chen YY, Erickson K, Teal SB, Kramer A, Cotton E, Ryan S, Jansson T, Powell TL. Decreased placental folate transporter expression and activity in first and second trimester in obese mothers. J Nutr Biochem. 2020 Mar; 77:108305. PMID: 31926453.
7. Vyas V, Guerra DD, Bok R, Powell T, Jansson T, Hurt KJ. Adiponectin links maternal metabolism to uterine contractility. FASEB J. 2019 Dec; 33(12):14588-14601. PMID: 31665924.
8. Castillo-Castrejon M, Jansson T, Powell TL. No evidence of attenuation of placental insulin-stimulated Akt phosphorylation and amino acid transport in maternal obesity and gestational diabetes mellitus. Am J Physiol Endocrinol Metab. 2019 12 01; 317(6):E1037-E1049. PMID: 31573844.
9. Ramzan AA, Bitler BG, Hicks D, Barner K, Qamar L, Behbakht K, Powell T, Jansson T, Wilson H. Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells. Mol Cell Biochem. 2019 Nov; 461(1-2):37-46. PMID: 31292831.
10. James-Allan LB, Arbet J, Teal SB, Powell TL, Jansson T. Insulin stimulates GLUT4 trafficking to the syncytiotrophoblast basal plasma membrane in the human placenta. J Clin Endocrinol Metab. 2019 May 21. PMID: 31112275.