Division of Reproductive Sciences investigators are fully committed to extending the tradition of research excellence set by the Department of Obstetrics and Gynecology and the University of Colorado School of Medicine. To this end, we have established research programs in all of the major subdivision of OB-GYN and some non-traditional areas, such as mammary gland biology. We have developed full-spectrum bench-to-bedside research programs in most of these areas, and have been participants in numerous clinical trials, both NIH and industry-sponsored. We have partnered with the community to engage our patients, through the Center for Women’s Health Research (CWHR) and through division-based community initiatives, and we have maintained old and created new collaborative research efforts that reach into geriatrics, metabolism and endocrinology, biochemistry, molecular biology, and –omics technology.
In the Bitler-Behbakht Lab our ultimate research objectives are to aid in the discovery and optimization of precision medicine-based anti-cancer therapeutics for gynecological cancers.
The Jansson-Powell Lab, research is focused on exploring the role of the placenta in determining fetal growth and long-term health.
McManaman Lab researchers investigate how cells store, metabolize, and traffic lipids at the molecular, structural, cellular and organ systems levels and how this contributes to defects in neonatal metabolic health and metabolic disorders
The Santoro Lab focused on the reproductive endocrinology of ovarian failure, menopause and perimenopause, and more recently on the effects of obesity on reproduction in women.
The Connell Lab seeks to understand the etiology and pathogenesis of Pelvic Organ Prolapse (POP) leading to more effective, targeted approaches to disease prevention and treatment.
The Johnson Lab has a goal of understanding the control of oocyte number and egg quality.
Moore Lab research is aimed at determining the physiological pathways involved and, in particular, the roles of AMPKα activation and epigenetic changes due to DNA methylation.
The Su Lab’s primary research focus is to better understand the molecular mechanisms underlying abnormal placental blood flow and function.
The Preterm Labor Research Laboratory (Hurt Lab) has a goal of understanding reproductive physiology and applying those findings to improve the health of women and infants.
Research in the Kumar Lab has a significant impact in understanding the physiology and pathology of the reproductive axis including abnormal reproductive tract development, infertility, ovarian aging, bone loss and cancer of the pituitary and gonads.
The Polotsky Lab studies how maternal obesity impacts the health of offspring by defining essential characteristics of FSH-ovarian interactions using a multidisciplinary approach.