T. Rajendra Kumar, PhD

Education
Postdoc, Baylor College of Medicine, Houston, TX
Postdoc, Vollum Institute, Oregon Health Sciences University, Portland, OR
PhD, University of Delhi, Delhi, India
MPhil, Central University of Hyderabad, Hyderabad, India
MSc, Central University of Hyderabad, Hyderabad, India

Contact
Research Complex 2, 3rd Floor
12700 East 19th Avenue
Room 3000B, MS 8613
Aurora, CO 80045

Phone: (303) 724-8689
Fax: (303) 724-3512

Research Interests
Dr. Kumar received his PhD from the University of Delhi, India and his postdoctoral training at the Vollum Institute, Oregon Health Sciences University in Portland, OR. He then moved to Baylor College of Medicine, Houston, TX, as a Research Associate and became an Assistant Professor in the Department of Pathology and Molecular & Cellular Biology. In 2004, he moved to University of Kansas Medical Center, Kansas City, KS, where he became a Tenured Professor in the Department of Molecular & Integrative Physiology and Director of the Center for Reproductive Sciences, Institute for Reproductive Health and Regenrative Medicine. He joined the Division of Reproductive Sciences in May 2016. His research was published in Nature, Nature Genetics, Cell, PNAS, J Clinical Investigation, Molecular and Cellular Biology, Journal of Biological Chemistry, Molecular and Cellular Endocrinology, and Endocrinology. He also edited textbooks entitled "Transgenics in Endocrinology," and "Gonadotropins: From Bench Side to Bedside."

Full List of Publications

Recent Publications

1. Kumar TR (2024). Gonadotropins Encyclopedia of Reproduction, Editor: Michael Skinner, Volume 2, Academic Press- Elsevier (In press).
2. Libby AE, Solt C, Jackman M, Sherk V, Foright RM, Johnson GC, Nguyen T-T, Breit M, Hulett N, Rudolph M, Roberson PA, Wellberg E, Jambal P, Scalzo RL, Higgins J, Kumar TR, Wierman, ME, Pan Z, Shankar K, Klemm DJ, Moreau KL, Kohrt WM, MacLean PS (2023). Effects of Follicle-Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function. American Journal of Physiology- Endocrinology, (In press).
3. Converse A, Liu Z, Patel J, Bousfield GR, Babu C, Kumar, TR* and Duncan FE* (2023). Hypoglycosylated FSH enhances oocyte quality via increased cell-to-cell interaction during mouse follicle development.. Development 150, dev202170. Doi:10.1242/dev.202170, * Co-Corresponding Authors.
4. McDonald R, Larsen M, Liu Z, Southekal S, Eudy J, Guda C and Kumar TR (2023). RNA-seq analysis identifies age-dependent changes in expression of mRNAs encoding N-glycosylation pathway enzymes in mouse gonadotropes. Molecular and Cellular Endocrinology.
5. Wang H, Liu Z, Larsen M, Hastings R, Gunewardena S and Kumar TR (2023). Identification of FSH-responsive genes in Sertoli cells during early postnatal mouse testis developmen Andrology 11:860-871.
6. Liu Z, Larsen, Lei Z, Rao CV and Kumar TR (2022). Lhb -/- and Lhr -/- double mutant mice phenocopy Lhb -/- or Lhr -/- single null mutants and display defects in Leydig cells and steroidogenesis. International Journal of Molecular sciences, 23:15725.
7. Morgan I, Coulombe JC, Larsen M, Liu Z, Ferguson VL and Kumar TR (2022). VISIONS: FSH and bone microarchitecture. Molecular Reproduction and Development, 89: 315-315.
8. Liu Z, Wang H, Larsen M, Gunewardana S, Cendali FI, Reisz JA, Akiyama H, Behringer RR, Ma Q, Hammoud, SS and Kumar TR (2022). The Solute Carrier Family 7 Member 11 (SLC7A1) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells Molecular and Cellular Endocrinology, 549:111641-111653.
9. Gera S, Sant D, Haider S, Korkmaz F, Kuo T, Mathew M, Perez-Pena H, Chen H, Batista R, Ma K, Cheng Z, Hadelia E, Robinson C, Macdonald A, Miyashiita S, Williams A, Xie H, Jebian G, Hirotaka M, Gumerova A, Ievleva K, Smith P, He J, Ryu V, DeMambro V, Quinn M, Meseck M, Kim S-M, Kumar TR, Iqbal J, New MI, Lizneva D, Rosen CJ, Hsueh AJ, Yuen T, Zaidi M (2020). First–in–Class Humanized FSH Blocking Antibody Targets Bone and Fat. Proceedings of The National Academy of Sciences (USA) 117: 28971- 28979.
10. Bousfield GR, May JV, Davis, JS, Dias JA and Kumar TR (2018). In vivo and in vitro impact of carbohydrate variation on human follicle stimulating hormone function. Frontiers in Endocrinology, 9: Article 216: 1-14 (doi: 10.3389/fendo.2018.00216).
11. Kumar TR. (2018). Extra-gonadal actions of FSH: a critical need for novel genetic models. Endocrinology 159: 2-8.