Natalie Davidson, PhD

Education
PhD (2020) in Computational Biology and Medicine, Weill Cornell Medical College
Advisor: Dr. Gunnar Ratsch

Contact
Research Complex 2
12700 East 19th Avenue
Room P15-3103, MS 8613
Aurora, CO 80045

Phone: (303) 724-5236
Fax: (303) 724-3512

Research Interests
Ovarian cancer is a heterogeneous disease with several histologically and molecularly defined subtypes. In addition to the subtype heterogeneity, there is variability within the tumor microenvironment and across different populations. My lab utilizes cutting-edge machine learning techniques to disentangle the molecular and clinical features of ovarian cancer and to identify drivers of tumor progression and treatment response.

Full List of Publications

Recent Publications

1. Davidson NR, and Greene CS (2023) Analysis of science journalism reveals gender and regional disparities in coverage. Highlighted in a Nature Magazine editorial. eLife doi:10.7554/eLife.84855.1
2. Hippen AA*, Davidson NR* and Greene CS (2022) Computational audits combat disparities in recognition. Nature Human Behaviour doi:10.1038/s41562-021-01279-2
3. Salloum D, Singh K, Davidson NR, Cao L, Kuo D, Sanghvi VR, Jiang M, Lafoz MT, Viale A, Ratsch G and Wendel HG (2022) A rapid translational immune response program in CD8 memory T lymphocytes. The Journal of Immunology doi:10.4049/jimmunol.2100537
4. Simmler P, Cortijo C, Koch LM, Galliker P, Angori S, Bolck HA, Mueller C, Vukolic A, Mirtschink P, Christinat Y, Davidson NR, Lehmann KV, Pellegrini G, Pauli C, Lenggenhager D, Guccini I, Ringel T, Hirt C, Marquart KF, Schaefer M, Rätsch G, Peter M, Moch H, Stoffel M, Schwank G (2022) SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer. Cell Reports doi:10.1016/j.celrep.2022.111266
5. Markolin P*, Davidson NR*, Hirt CK, Chabbert CD, Zamboni N, Schwank G, Krek W and Rätsch G (2021) Identification of HIF-dependent alternative splicing in gastrointestinal cancers and characterization of a long, coding isoform of SLC35A3. Genomics doi:10.1016/j.ygeno.2020.12.039
6. Stark SG, Gut G, Rätsch G^ and Davidson NR^ (2021) pmVAE: Learning Interpretable Single-Cell Representations with Pathway Modules. ICML Computational Biology Workshop
7. PCAWG Transcriptome Core Group*, Calabrese C*, Davidson NR*, Demircioğlu D*, Fonseca NA*, He Y*, Kahles A*, Lehmann KV*, Liu F*, Shiraishi Y* and Soulette CM*, et al. (2020) Genomic basis for RNA alterations in cancer. Included as part of a Nature special collection Nature doi:10.1038/s41586-020-1970-0
8. Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J,Saqcena M, Singh K and Wendel HG (2019) EIF1AX and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC. Cancer discovery doi:10.1158/2159-8290.CD-18-0606
9. Davidson NR, Godfrey KR, Alquaddoomi F, Nola D and DiStefano III JJ (2017) Disting: A web application for fast algorithmic computation of alternative indistinguishable linear compartmental models. Computer Methods and Programs in Biomedicine doi:10.1016/j.cmpb.2017.02.025
10. Waldman YY, Biddanda A, Davidson NR, Billing-Ross P, Dubrovsky M, Campbell CL, Oddoux C, Friedman E, Atzmon G, Halperin E and Ostrer H (2016) The genetics of Bene Israel from India reveals both substantial Jewish and Indian ancestry. PLoS One doi:10.1371/journal.pone.0152056