Gynecologic Oncology Research Group

The discovery and optimization of precision medicine-based anti-cancer therapeutics.

Ovarian and endometrial cancers are the deadliest and most common gynecologic malignancies, respectively. Notably, through research and clinical efforts over the past two decades, progress has been made in effectively managing these cancers, but there is still work to be done! Our ultimate research objectives are to aid in the discovery and optimization of precision medicine-based anti-cancer therapeutics.

With respect to ovarian cancer, our labs have three significant areas of on-going research, including early detection and prevention (Dr. Behbakht), disease progression and metastasis (Dr. Bitler), and novel therapeutic interventions (Drs. Bitler/Behbakht). Within these areas of research, we emphasize the epigenome, metabolome, and signaling pathways responsible for ovarian cancer tumorigenesis, disease dissemination, and therapy resistance. Further, the lab works closely with the Division of Gynecologic Oncology to ensure the translatability of our discoveries.

With respect to endometrial cancer, our labs are researching underlying genetic mechanisms of disease recurrence and developing precision medicine approaches to prevent disease recurrence (Drs. Corr/Moroney/Bitler). Based on previous research and clinical findings, we have honed in the Wnt/beta-catenin pathway and immune checkpoint as therapeutic targets.


Contact Info

Olivia Castillo
Division Administrator
12700 East 19th Avenue
Room 3000D, MS 8613
Aurora, CO 80045

Phone: (303) 724-4144