Basic Science Research

Basic Science Research


Basic science research delves into fundamental biological, chemical, and physical processes, serving as the cornerstone for translating discoveries into clinical applications and medical advancements. Employing animal experiments, cell studies, and computational models, our research aims to better understand tumor formation, treatment resistance, genetic and molecular pathways, the tumor microenvironment, cellular signaling, and metastasis.  

Our Research


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Genetic and Molecular Pathways

Identifying and investigating mutations, such as BRCA1 or BRCA2, and molecular alterations in genes and proteins driving ovarian cancer formation, progression, metastasis, and subtype variations across populations.

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Tumor Microenvironment (TME) and Cell Signaling

Studying the interaction between cancer cells and their surrounding environment, including immune and stromal cells as well as signaling molecules. The microenvironment significantly influences tumor behavior and treatment responses, especially in ovarian cancer. 

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Mechanism of Drug Resistance

Understanding how ovarian cancer cells develop resistance to chemotherapy and other treatments and finding ways to overcome this resistance.

Understanding these mechanisms and processes is crucial for identifying potential targets and developing effective treatments. 

 

Contact Info

Freda Ireigbe, MHA
OCIG Program Manager
13001 East 17th Place
Suite C5010
Aurora, CO 80045

Email: ocig@cuanschutz.edu
Phone: (303) 724-2435

 

 

Contact Info

Freda Ireigbe, MHA
OCIG Program Manager
13001 East 17th Place
Suite C5010
Aurora, CO 80045

Email: ocig@cuanschutz.edu
Phone: (303) 724-2435

 

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