Identifying and investigating mutations, such as BRCA1 or BRCA2, and molecular alterations in genes and proteins driving ovarian cancer formation, progression, metastasis, and subtype variations across populations.
Studying the interaction between cancer cells and their surrounding environment, including immune and stromal cells as well as signaling molecules. The microenvironment significantly influences tumor behavior and treatment responses, especially in ovarian cancer.
Understanding how ovarian cancer cells develop resistance to chemotherapy and other treatments and finding ways to overcome this resistance.