Christians Lab
Primary Appointment: Professor, Anesthesiology
Secondary Appointment: Professor, Pathology
Professor (apl.) für Experimentelle und Klinische Pharmakologie und Toxikologie, Medizinische Hochschule Hannover, Hannover, Germany
Education​
- MD (highest honors, “summa cum laude”), Medizinische Hochschule Hannover, Hannover, Germany
- PhD (“Habilitation”), Experimentelle und Klinische Pharmakologie und Toxikologie, Medizinische Hochschule Hannover, Hannover, Germany
- Post-Doctoral Fellowships:
- Biopharmaceutical Sciences (Dr. L.Z. Benet), University of California, San Francisco
- Cardiothoracic Surgery and Transplant Immunology (Dr. R.E. Morris), Stanford University Medical School
- Residencies and Board Certifications:
- Facharzt für Pharmakologie and Toxikologie, Medizinische Hochschule Hannover, Hannover, Germany
- Facharzt für Klinische Pharmakologie, Medizinische Hochschule Hannover, Hannover, Germany
- American Board of Clinical Pharmacology
Contact Information
12705 E Montview Blvd., Suite 200
Aurora, Colorado 80045
Direct Telephone: (303) 724-5665
Work Telephone: (303) 724-5670
Email: uwe.christians@cuanschutz.edu
Research Interests
My research interests include pharmacokinetic and pharmacodynamic therapeutic drug monitoring, clinical biochemistry, biochemical toxicology, and drug metabolism.
Research Description
My research has focused on the interactions between energy metabolism, mitochondrial metabolism and the mTOR pathway. This includes the toxicodynamic interactions between calcineurin and mTOR pathway inhibitors, ageing, metabolic diseases, oxidative stress, ischemia/ reperfusion injury and drug-coated coronary stents and balloons.