Age 2.5-45 with a parent, brother, sister or child with T1D
Age 2.5-20 with a grandparent, aunt/uncle, cousin, niece/nephew or half-sibling with T1D
Age 2.5-45 with evidence of autoantibodies from outside TrialNet
Monitoring
Screened through TrialNet and found to have at least 1 autoantibody
Have a relative with T1D
Procedures involved:
Willing to give informed consent/assent
Single Autoantibody: annual blood draw to test for the development of multiple autoantibodies
Multiple autoantibodies: annual or semi-annual visits depending on glucose tolerance to a 2 hour OGTT involving placement of IV and drinking a glucose beverage after an 8 hour fast