Maki Nakayama MD

  • Anschutz Campus - Sch of Med - BDC Basic Research

Email Address:maki.nakayama@cuanschutz.edu

Primary Phone:303-724-4076

Mailing Address:
  • CU Anschutz

Barbara Davis Center for Diabetes

1775 North Aurora Court

Aurora, CO 80045

Dr. Nakayama joined the BDC faculty in 2009. Her research strives to understand the mechanism of initiation of anti-beta cell autoimmunity. She focuses on the tri-molecular complex consisting of antigen, major histocompatibility complex (MHC), and T cell receptor (TCR) that could be a key component for the development of T1D.  Her laboratory explores antigen specificity of autoreactive T cells having different functions (i.e. pathogenic vs regulatory T cells) that target pancreatic beta cells; the role of T cells expressing specific TCRs in the development of T1D using an animal model; the potential of TCR sequences to be used as T cell biomarkers to predict the development of type 1 diabetes as well as recurrence of hyperglycemia after clinical therapeutic trials; lastly, exploring the mechanism of transplantation failure in T1D patients.  Dr. Nakayama has been part of the JDRF-Helmsley nPOD missions, which is an international network of characterizing pancreata from cadaveric organ donors with T1D. 

Education, Licensure & Certifications

MD: Kobe University School of Medicine, Kobe, Japan (1994)
PhD: Kobe University School of Medicine, Kobe, Japan (2002)

Research Division

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