COMIRB #: 06-0420
Purpose of research study:
- To determine the relative contribution of genetic and environmental factors to the early stages of and progression to type 1 diabetes and related autoimmune diseases
- Eligible participants include twins affected with type 1 diabetes and unaffected twins, non-twin siblings and parents. Type 1 Diabetes in the affected participant is defined as onset <40 years old and the use of daily insulin therapy within one year of diagnosis. Participants must be between 6 months and 80 years old.
- A blood draw will be done to obtain DNA and serum samples. Samples are analyzed for diabetes autoantibodies, other autoantibodies, and markers associated with risk of developing diabetes.
- A swab of the inside of the cheek might also be collected for DNA. Same sex twins will be tested for genes to verify if they are identical or fraternal.
Duration of participation:
- The first visit will take about 30 minutes. Depending on the results of the tests, participants will be asked to come in for a visit every 6-12 months. The study will continue until the participant withdraws or until funding is stopped.
Principal investigator: Andrea Steck, MD
Study Coordinator: Morgan Sooy, (303) 724-5686