Translational Clinical Research in the Department of Neurosurgery
| Treatment Area | Title | Principal Investigator | Eligibility and Information |
| Biobanking | Nervous System Biorepository Protocol | Kevin Lillehei, MD | ANTHONY.FRINGUELLO@CUANSCHUTZ.EDU; 303-724-4136 |
| Brain Injury | University of Colorado Department of Neurosurgery Exosomes in Traumatic Brain Injury (TBI) Protocol | Kevin Lillehei, MD | TERRA.ORNELAS@CUANSCHUTZ.EDU; |
| Brain Injury, Stroke | Impact of Fever Prevention in Brain Injured Patients (INTREPID) | Luis Cava, MD | TERRA.ORNELAS@CUANSCHUTZ.EDU; 303-724-7970 |
| Brain Tumor | Vigilant ObservatIon of GlIadeL WAfer ImplaNT (VIGILANT) Registry: A Multicenter, Observational Registry to Collect Information on the Safety and Effectiveness of Gliadel® Wafer (Carmustine Implant) Used in Usual Medical Practice | Kevin Lillehei, MD | TERRA.ORNELAS@CUANSCHUTZ.EDU; 303-724-7970 |
| Chiari/Syringomyelia | Park Reeves Syringomyelia Research Symposium | Brent O’Neill, MD | KIM.POPPLETON@childrenscolorado.org; |
| Craniopharyngioma | aDvancing Treatment for Pediatric Craniopharyngioma (ATPC): Prospective Pilot Study Idnetifying Clinically Relevant Biological Targets for Medical Therapy | Tod Hankinson, MD | SUSAN.STAULCUP@CUANSCHUTZ.EDU; |
| Epilepsy | Pediatric Brain Lesions Associated with Intractable Epilepsy: Molecular Biology in Comparison to Aggressive Brain Tumors | Allyson Alexander, MD | KIM.POPPLETON@childrenscolorado.org; 720-777-5281 |
| Epilepsy | Using chronic epilepsy monitoring to study the role of parietal and occipital cortex in movement initiation and perception | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; |
| Epilepsy | SLATE- Stereotactic Laser Ablation for Medial Temporal Lobe Epilepsy | Steven Ojemann, MD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Epilepsy | Identifying relevant seizure biomarkers from RNS® System recorded electrocorticography for the development of optimized seizure detection algorithms. | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Epilepsy | Association of depth recordings from the temporal cortex with sleep pattern detection and characterization of sleep dysfunction in patients with refractory epilepsy | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Epilepsy | Impact of Surgical intervention treatment on sleep dysfunction in patients with refractory epilepsy. | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Epilepsy | Barriers to Epilepsy Surgery- Survey | Steven Ojemann, MD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Epilepsy | Neurophysiological investigation of epistemic veracity in the context of ambiguous videographic evidence | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Meningioma | Correlation of pre-operative MRI for olfactory tract imaging with intraoperative findings and olfaction outcome | Samy Youssef, MD | TERRA.ORNELAS@CUANSCHUTZ.EDU; 303-724-7970 |
| Movement Disorders | Sensory Gating Measured with Microelectrode Recording during Deep Brain Stimulation Surgery | Judith Gault, PhD | JUDITH.GAULT@CUANSCHUTZ.EDU; 303-724-4132 |
| Movement Disorders | Automatic measurement of hand movements toward development of an objective assessment of primary motor symptoms in Parkinson’s disease and Essential Tremor | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Neurospychology | University of Colorado School of Medicine Neuropsychology Database | Brian Hoyt, PhD | JENNIFER.MAITLEN@CUANSCHUTZ.EDU; |
| Parkinson’s disease and schizophrenia | Leveraging ethical dissection among capacity, beneficence, and justice in clinical trials of neurotherapeutics in the severely disabled | Judith Gault, PhD | JUDITH.GAULT@CUANSCHUTZ.EDU; |
| Parkinsons Disease | Subthalamic nucleus deep brain stimulation effect on olfactory dysfunction in Parkinson’s disease | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Parkinsons Disease | Understanding the role of subcortical oscillations in human sleep dysregulation | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Parkinsons Disease | Subthalamic nucleus activity during habitual versus controlled movement | John Thompson, PhD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Parkinsons Disease | RESTORE-1: A Randomized, Placebo Surgery Controlled, Double-blinded, Multi-center, Phase 2 Clinical Trial, Evaluating the Efficacy and Safety of VY-AADC02 in Advanced Parkinson’s Disease with Motor Fluctuations | Steven Ojemann, MD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Parkinsons Disease | A Post-Market Study Evaluating the Safety of Infinity DBS System with MR Conditional Labeling | Steven Ojemann, MD | PAMELA.DAVIDGERECHT@CUANSCHUTZ.EDU; 303-724-4134 |
| Skull Lesions (Calvarial Langerhans Cell Histiocytosis) | Non-Operative Management of Suspected Calvarial Langerhans Cell Histiocytosis | Michael Handler, MD | KIM.POPPLETON@childrenscolorado.org; |
| Spine | A Double Blinded Randomized control trial in Outcomes for Lumbar Decompressions with use of Liposomal Bupivicaine | Peter Witt, MD | TERRA.ORNELAS@CUANSCHUTZ.EDU; 303-724-7970 |