New Clinical Trial
When his team of researchers injected the GM-CSF into the brains of mice with Alzheimer’s, it cut the amyloid plaque in half. When the compound was injected under their skin, the mice improved their scores navigating a water maze immensely.
GM-CSF has been FDA-approved and in use since 1991 as the prescription drug Leukine, which stimulates
Its long-standing safety record made the next step easier.
In 2011, Potter and his colleagues at the University of South Florida Health Byrd Alzheimer’s Institute launched a Phase II clinical trial to look at the safety and efficacy of the drug in Alzheimer’s disease patients.
This fall, a similar trial will get underway at CU.