If you think you may be eligible for one of these studies or if you would like more information, please contact us at NeuroResearch@cuanschutz.edu or 303-724-4644.
Purpose: to examine how inflammation and COVID-19 exposure influences brain health. Data gathered from this study will be used to better understand how inflammation may or may not disrupt thinking and memory.
Timeline: two study visits over the course of two years
Key Eligibility Criteria: age: 60+ years old, in good general health, have NOT been diagnosed with a memory disorder, willing to undergo 2 lumbar punctures over the course of the study
Purpose: to better understand how a mild traumatic brain injury in late life relates to inflammation, markers of Alzheimer’s disease related proteins, and clinical functioning over time
Timeline: two study visits over the course of one year (a baseline and a one year follow-up visit)
Key Eligibility Criteria: age: 65+ years old, in good general health, have NOT been diagnosed with a memory disorder, have had a concussion within the past 5 years
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: Mild cognitive impairment (MCI) or dementiaORhave NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
Conversational Speech Analysis (CSA) Study (18-0456)
Purpose: to learn more about how speech changes over time in adult populations, understand how those changes reflect changes in cognition, and develop new ways of detecting MCI and dementia using everyday speech
Purpose: to learn more about how speech changes over time in adult populations, understand how those changes reflect changes in cognition, and develop new ways of detecting MCI and dementia using everyday speech
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 40-95 years old
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
Currently Enrolling Studies
Conversational Speech Analysis (CSA) Study (18-0456)
Purpose: to learn more about how speech changes over time in adult populations, understand how those changes reflect changes in cognition, and develop new ways of detecting MCI and dementia using everyday speech
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 40-95 years old
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
Purpose: The ARTFL LEFFTDS Longitudinal Frontotemporal Dementia (ALLFTD) study aims to evaluate sporadic (s-) and familial (f-) frontotemporal lobar degeneration (FTLD) patients and asymptomatic family members of f-FTLD patients, characterizing the cohorts longitudinally and informing clinical trial design (Biofluid-Focused and Longitudinal arms available)
ALLFTD Biofluid Timeline: one-time visit with questionnaires, neurological exam, blood drawn, and optional lumbar puncture
ALLFTDLongitudinal Timeline: annual visit to the clinic, each lasting 2–3 days, with questionnaires, thinking and memory questions, neurological exam, blood drawn, and an MRI
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
Purpose: to understand how the brain makes different facial expressionsusing high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions
Timeline: one study visit that will last approximately one hour
Key Eligibility Criteria: diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, age: 18-75 years old, are right handed
