University of Colorado Anschutz Medical Campus

NEUROVASCULAR/STROKE RESEARCH

The Neuro-Hospitalists team at the University of Colorado is a highly specialized group of physicians who provide expert care for patients with a wide range of acute neurological conditions. We provide timely and effective interventions to improve patient outcomes, and our team is available around the clock to issue rapid responses to stroke emergencies. Our clinical research program aims to advance the field of neurovascular medicine, with a particular focus on investigating new diagnostic and treatment approaches for stroke. Our goal is to provide the highest quality of care for our patients and improve outcomes for those with neurovascular and stroke-related conditions.

Actively Enrolling Studies

Currently Enrolling Studies

CADASIL (22-0235)

Investigator: Karen Orjuela, MD
Purpose: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common heritable cause of vascular dementia, but many of the early symptoms of the disease remain poorly understood. This study is designed to look at how a person's body, brain, and behavior change throughout the stages of this disease, and what factors might serve as additional risks or protective factors.
Timeline: 3 in-person study visits over 5 years.
ClinicalTrials.gov Identifier: NCT05677880
Key Eligibility Criteria:
- CADASIL Participants:
  - Age: 18+ years old
  - positive NOTCH3* genetic testing; or a positive skin biopsy; or willingness to have a NOTCH3 genetic test prior to enrolling and are a -risk for, or diagnosed clinically, with CADASIL
- CADASIL Participant Chosen Companion:
  - Same criteria as CADASIL participants except are or were at risk for CADASIL but have Negative NOTCH3* genetic testing

Get Connected

If you think you may be eligible for one of these studies or if you would like more information, please fill out our Neurology Research Interest Web Form or contact us at N euroResearch@CUAnschutz.edu or 303-724-4644.

Principal Investigators

Patrick Bosque, MD

William Jones, MD

Karen Orjuela, MD

Sharon Poisson, MD

Local Neurology Events

The Brain "101" Community Education Event

(Recurring Event - Every week on Tuesday)

Apr 30, 2024 | 07:00 AM - 08:00 PM Cost/fee: FREE

6-week virtual education experience

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More Information

Walk MS: Denver 2024

May 4, 2024 | 07:30 AM - 12:00 PM

Cost/fee: FREE

Walk MS unites the MS community in the largest gathering of its kind to raise funds and make a difference for everyone living with MS.

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Website

2024 Walk to End Alzheimer's

Sep 21, 2024 | 08:00 AM - 05:00 PM

Cost/fee: FREE

The world's largest fundraiser for Alzheimer's care, support and research.

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Website

Further Resources

American Stroke Foundation

Our mission is to empower stroke survivors and their families to overcome the challenges of life after stroke.

American Stroke Association

The American Stroke Association is a relentless force for a healthier world with fewer strokes — the No. 2 cause of death worldwide and a leading cause of disability. As champions for health equity, we commit to: identify and remove barriers to health care access and quality, and advance cardiovascular health for all.

Neurology (SOM)

CU Anschutz

Research Complex II

12700 East 19th Avenue

5018

Aurora, CO 80045

303-724-4328

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Tools & Resources

CU Campuses

CU Anschutz Medical Campus

Department of Neurology

School of Medicine

NEUROVASCULAR/STROKE RESEARCH

Actively Enrolling Studies

Healthy Volunteer Research Webpage

Get Connected