HEALTHY VOLUNTEERS

DREAMS (19-0393)   

• Investigator: Teri Schreiner, MD, MPH  
• Purpose: to learn more about the risk factors for and causes of MS by studying children who are first degree relatives of people with MS.
• Timeline: a single 3-4 hour study visit (includes MRI and blood draw).
• Key Eligibility Criteria: age 10-17 years old, have parent or sibling with MS, no diagnosis of MS or early symptoms of MS.

RISE-MS (17-1884)   

• Investigator: Enrique Alvarez, MD, PhD and John Corboy, MD 
• Purpose: to learn more about the risk factors for and causes of MS by studying first degree relatives of people with MS.
• Timeline: a single 2-3 hour study visit (includes MRI and blood draw).
• ClinicalTrials.gov Identifier: NCT03586986 
• Key Eligibility Criteria: age 10-17 years old, have parent or sibling with MS, no diagnosis of MS or early symptoms of MS.
  

Cytokine Observational Study (18-1356)  

• Investigator:  Maureen Leehey, MD, FAAN  
• Purpose: to learn more about the level of inflammatory and other markers in the blood of patients with Parkinson’s disease (PD), essential tremor (ET), and healthy volunteers.
• Timeline: one time blood draw.
• Key Eligibility Criteria: have NOT been diagnosed with PD or ET, age: 60-75 years old.

Michael J. Fox Foundation PPMI 2.0 (20-1204) 

• Investigator: Michelle Fullard, MD, MSCE  
• Purpose: to continue to obtain information from people with and without Parkinson’s disease (PD) so that researchers may better understand how PD progresses, in order to inform better treatments.
• Timeline: 2 visits annually for up to 7 years.
• ClinicalTrials.gov Identifier: NCT04477785
• Key Eligibility Criteria: have NOT been diagnosed with PD, do NOT have a first degree relative with PD, age: 30+ years old OR have NOT been diagnosed with PD, have a first degree relative with PD, age: 60+ years old.
  

Facial Expressions Study (17-0599)

• Investigator: Peter Pressman, MD
• Purpose: to understand how the brain makes different facial expressions using high speed videography, learn more about how neurological disorders may impact a person’s facial movements and expressions, and develop the groundwork for a diagnostic tool that would detect differences between a person’s facial movements/expressions and their emotions.
• Timeline: one study visit that will last approximately one hour.
• CUACC Website: click here
• Key Eligibility Criteria: age: 18-75 years old, diagnosis: mild cognitive impairment (MCI) or dementia OR have NOT been diagnosed with a memory disorder, are right handed.

DN (19-3004)

•  Study Title: Participants Needed for Research Study About Diabetes and Neuropathy.
• Investigator: Vera Fridman, MD
• Purpose: to learn more about the underlying causes of diabetic neuropathy by looking for the presence of abnormal molecules in the blood and skin and comparing them in people with and without Type 2 Diabetes.
• Procedures: blood draw, skin biopsy, neurological and physical exam.
• Timeline: 2 study visits which will occur within 30 days of each other.
• Key Eligibility Criteria: age: 45-65 years old, have NOT been diagnosed with Type 2 Diabetes (T2D).