Haugen/French Lab

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Dr. Haugen is a physician-scientist who sees patients with thyroid cancer and does basic/translational and clinical research on thyroid cancer therapeutics.  More recently, his research group and collaborators have been using multi-omic approaches and single cell RNA sequencing to better understand advanced thyroid cancer in humans and animal models.

Research Topics


Here are the research topics for the Haugen Lab:

1

To test the novel combination therapy of taxanes and inhibitors of the spindle assembly checkpoint pathway in preclinical models of anaplastic thyroid cancer

This lab is currently NIH funded - R01 CA233546
2

To determine the effects of metabolism and sex in thyroid cancer progression using human studies and animal models.

3

To explore complementary therapies to BRAF inihibitor + MEK inhibitor (in BRAF mutated tumors) and MEK inhibitor in (in RAS mutated tumors) to improve efficacy of these therapies

The experiments use transgenic mouse models and single cell sequencing approaches.

Here are the research topics for the French Lab:

1

Characterizing the T cell response in human thyroid tumors. We expand tumor-infiltrating T cells from thyroid tumors for TCR clonality and antigen specificity studies

2

Investigating immune-modulating therapies for advanced thyroid cancers in preclinical mouse models and clinical trials

Lab Personnel


Haugen/French Lab Personnel
 

 

Vibha Sharma, PhD

Research Associate

Uma Pugazhenthi headshot

 

Uma Pugazhenthi

Research Laboratory Intermediate Professional

 

 

Jacob Calhoun

Research Laboratory Intermediate Professional

 

 

Amanda LaGreca, MD

Assistant Professor

 

 

Nikita Pozdeyev, MD, PhD

Assistant Professor

Min-Ji Jeon headshot

 

Min-Ji Jeon, MD, PhD

Visiting Research Scholar
Assistant Professor

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