MS/Neuroimmunology

Clinical Research


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If you think you may qualify for one of these studies, please contact Neurology Research at (303) 724-4644 or NeuroResearch@CUAnschutz.edu

 

 

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Relapsing Remitting MS

20-1569

A Phase 1 Study of the Safety and Tolerability of Single and Multiple Doses of ANK-700 in Patients with Relapsing-Remitting Multiple Sclerosis

Amanda Piquet, MD

Clinical Trials

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20-0705

A Single-Arm, Prospective, Multicentre, Open-Label Study to Evaluate Ofatumumab Treatment Effectiveness and Patient Reported Outcomes in Patients with Relapsing Multiple Sclerosis Transitioning from Dimethyl Fumarate or Fingolimod Therapy (ARTIOS)

Enrique Alvarez, MD, PhD

Clinical Trials

n/a

19-1621

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

John Corboy, MD

Clinical Trials

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20-3026A Phase III Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Teriflunomide in Adult Patients with Relapsing Multiple Sclerosis (FENhance)Enrique Alvarez, MD, PhDClinical TrialsSee Advertisement
20-1101A Phase 3, Randomized, Double-Blind Efficacy and Safety Study Comparing SAR442168 to Teriflunomide (Aubagio) in Participants with Relapsing Forms of MS (GEMINI I)Enrique Alvarez, MD, PhDClinical TrialsSee Advertisement
20-1047A Phase 3, Randomized, Double-Blind Efficacy and Safety Study Comparing SAR442168 to Placebo in Participants with Non Relapsing Secondary Progressive MS (HERCULES)Enrique Alvarez, MD, PhDClinical TrialsSee Advertisement
19-2420A Multicenter, Longitudinal, Open-Label, Single-Arm Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated with Ozanimod (Rpc-1063)Amanda Piquet, MDClinical Trialsn/a

20-2135

A Single-Arm, Prospective, Multi-Center, Study to Explore Maintained Efficacy with Ofatumumab Therapy in Patients with Relapsing Multiple Sclerosis who Discontinue Intravenously Delivered Anti-CD20 Monoclonal Antibody (aCD20 mAb) Therapy (OLIKOS)

Enrique Alvarez, MD, PhD

Clinical Trials

n/a

Primary Progressive MS

20-0454

A Phase 1, Two-part, Open-label Dose-escalation and Double-blind, Placebo-controlled Dose-expansion Study with an Open-label Extension to Evaluate the Safety and Efficacy of ATA188 in Subjects with Progressive Multiple Sclerosis

Enrique Alvarez, MD, PhD

Clinical Trials

n/a

21-2663A Phase III Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared with Ocrevus in Adult Patients with Primary Progressive MS (FENtrepid)Enrique Alvarez, MD, PhDClinical Trialsn/a
20-1100A Phase 3, Randomized, Double-Blind Efficacy and Safety Study Comparing SAR442168 to Placebo in Participants with Primary Progressive MS (PERSEUS)Enrique Alvarez, MD, PhDClinical TrialsClinical Trials
20-1853A Phase IIIb Multicenter, Randomized, Double-Blind, Controlled Study to Evaluate the Efficacy, Safety and Pharmacokinetics of a Higher Dose of Ocrelizumab in Adults with Primary Progressive MS (Gavotte)Enrique Alvarez, MD, PhDClinical TrialsSee Advertisement
Newly Diagnosed MS

18-1633

Determining the Effectiveness of Early Intensive Versus Escalation Approaches for the Treatment of Relapsing-Remitting Multiple Sclerosis (DELIVER-MS)

Enrique Alvarez, MD, PhD

Clinical Trials

n/a

20-1000Central Vein Sign: A Diagnostic Biomarker in MS (CAVS-MS)Enrique Alvarez, MD, PhDClinical Trialsn/a
Healthy Volunteers 

17-1884

Risk Factors in Early Multiple Sclerosis (RISE-MS)

John Corboy, MD

Clinical Trials

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19-0393

Detection and Risk in Early MS (DREAMS)

Teri Schreiner, MD, MPH

n/a

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Exercise Studies

20-0695

Low Load Resistance Training Using Blood Flow Restriction for People with Multiple Sclerosis with Marked Mobility Restriction

Mark Manago, DPT, PhD, PT, NCS

Clinical Trials

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18-0179

Comparative Effectiveness of an Exercise Intervention Delivered via Telerehabilitation and Conventional Mode of Delivery

Jeffrey Hebert, PT, PhD

Clinical Trials

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20-1527

Proximal Resistance Training to Improve Walking Capacity and Physical Activity in People with Multiple Sclerosis

Mark Manago, DPT, PhD, PT, NCS

Clinical Trials

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Bio and Tissue Banks

12-0968

Rocky Mountain Multiple Sclerosis Center (RMMSC) Biorepository for the Study of Neuroimmunological Disorders

Enrique Alvarez, MD, PhD

Clinical Trials

n/a

09-0952

Rocky Mountain MS Center Tissue Bank

John Corboy, MD

Clinical Trials

n/a