Phase III trial comparing the effect of video vs direct laryngoscope on first pass success of emergency tracheal intubation of critically ill adults in the acute care setting.
Phase III trial comparing the effect of preoxygenation with non-invasive positive pressure ventilation to preoxygenation with a facemask on the incidence of hypoxemia, among critically ill adults undergoing emergency tracheal intubation.
Phase III trial platform to evaluate the efficacy and safety of antiviral treatments for hospitalized COVID-19 patients
ACTIV-4 Host Tissue
Phase III platform trial evaluating the efficacy and safety of host-directed interventions to improve outcomes for hospitalized COVID-19 patients.
National network using real-world data to evaluate vaccine effectiveness of COVID-19 and influenza vaccination in preventing hospitalizations and deaths.
Multicenter study of the dissemination, implementation, and real-world effectiveness of neutralizing monoclonal antibody and other antiviral treatments for high-risk outpatients with COVID-19
National longitudinal observational cohort study to understand, prevent, and treat long-term health effects related to post-acute sequelae of SARS-CoV-2 (PASC).
STRIVE – coming soon
Phase III, out-patient clinical trial to test the efficacy and safety of the antiviral agent lopinavir/ritonavir to prevent disease progression and improve recovery in outpatients with COVID-19.