Dept. of Biochemistry and Molecular Genetics
Characterization large macromolecular complexes
Messenger RNA Production by RNA polymerase II
An expanded view of telomeres and their roles in safeguarding genome stability
Cancer metabolism and (red) blood cell biology
Cancer: understanding its evolution and targeting its dependencies
Viral protein/host protein interactions and enzyme motions
Quantitative and functional proteomics, extracellular matrix processing and organization
Molecular causes and phenotypic consequences of the broadly defined family of genomic features known as structural variations (SVs)
Nucleic acid repair
mRNA surveillance in health and disease
Understanding how G protein-coupled receptors (GPCRs) are regulated within cells
Mechanisms of chromatin-mediated gene silencing
Cell cycle regulation of DNA replication
The dynamics of RNA regulatory networks
Structural mechanisms of chromatin signaling
Telomere Functions in Aging and Cancer
Protein structure, function and sequence evolution
In vivo nucleosome structure and dynamics
RNA stability and translation
Subcellular RNA localization
NMR spectroscopy for the elucidation of conformation and communication networks within and between proteins and nucleic acids
Developing technologies that enable tracking the full life cycle of proteins
Molecular mechanism of pre-mRNA splicing; drug design targeting transcriptional complex in breast cancer
Structural biology of membrane proteins and protein complexes