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Julia Promisel Cooper, Chair
As biochemists and molecular geneticists, we are in the midst of an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.
Maximal synergy and depth of thinking require an open, vibrant research environment in which people of all backgrounds thrive. We are passionately devoted to enhancing diversity and upholding uncompromised equity and anti-racism. These principles, along with the close proximity of BMG to other outstanding basic and clinical departments as well as several hospitals, vastly enhance our opportunities for collaboration and translation of paradigm-shifting basic discoveries to the clinic and beyond.
Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8
Cooper Lab – March 2021 - Nature
Bentley Lab – February 2021 – Molecular Cell
Vögeli Lab - February 2021 - Nature Communications
Vögeli Lab - February 2021 - JMB
Structural and mechanistic bases for a potent HIV-1 capsid inhibitor
Asturias Lab - October 2020 - Science
Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU
Hesselberth Lab - September 2020 - RNA Journal
Comprehensive Chromosome End Remodeling during Programmed DNA Elimination
Davis Lab - September 2020 - Current Biology
Kieft Lab - August 2020 - RNA Journal
A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution
DeGregori Lab - July 2020 - Scientific Reports
The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition
Rissland Lab - June 2020 - eLife
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status
D’Alessandro Lab - June 2020 - JCI Insight
FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences
Taliaferro Lab - June 2020 - eLife
Zhao Lab - June 2020 - Cancer Research
Congratulations to all recent postdoc and graduate student awardees!
![]() | March 2021 Welcome to BMG, Melissa Haendel! Dr. Haendel will be the Chief Research Informatics Officer for the Anschutz Medical Campus as well as a Professor in BMG. |
![]() | March 2021 David Pollock contributed scientific expertise to the Washington Post article “An Accelerated cauldron of evolution: Covid-19 patients with cancer, HIV, may play a role in emergence of variant”. |
March 2021 Monika Dzieciatkowska, Julie Haines, and Angelo D’Alessandro’s research was highlighted in the CU Anschutz Medical Campus News – “Scientists Discover Ways of Making Old Blood New Again” | |
![]() | March 2021 Elan Eisenmesser’s COVID-19 research was highlighted in the CU Anschutz Medical Campus news – “Researchers Target Nucleocapsid Protein to Combat COVID-19” |
![]() | February 2021 James DeGregori’s research was highlighted in the CU Anschutz Medical Campus news - “The Impacts of Aging on Cancer” |
![]() | February 2021 David Pollock’s COVID-19 research was highlighted in the CU Anschutz Medical Campus news - “Coronavirus Mutates Fast; New Strain Can Arise in Single Patient” |
![]() | February 2021 Steve Bonilla (Postdoctoral Scholar, Kieft Lab) was awarded the Howard Hughes Medical Institute Hanna Grey Fellowship. Congratulations! |
![]() | January 2021 Elan Eisenmesser’s recent streptococcus pneumoniae publication was highlighted in Nature Communications Focus Structural biology, biochemistry and biophysics. |
December 2020 Quentin Vicens (Research Asst. Prof.) and Jeffrey Kieft were awarded an NIH R21 from NIAID to study xrRNAs in the alphavirus supergroup. Congratulations! | |
![]() | November 2020 Angelo D’Alessandro’s COVID-19 red blood cell research was highlighted in the CU Anschutz Medical Campus news - “Attack on Red Blood Cells a Prime Suspect in COVID’s Debilitating Effects” |
![]() | November 2020 Welcome to BMG, Casey Greene! Dr. Greene will be the Director of the new Center for Health Artificial Intelligence and Chair of the Department of Biomedical Informatics, both of which will be forming over the next year. |
![]() | October 2020 Travis Nemkov’s (postdoc D'Alessandro lab) recent publication was highlighted in the CU Anschutz Medical Campus news - “Metabolomics: The Science Behind a Tour de France Winner” |
![]() | October 2020 Suja Jagannathan was awarded an RNA Society Colorado RNA Club grant. Congratulations! |
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