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Julia Promisel Cooper, Chair
As biochemists and molecular geneticists, we are in the midst of an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.
Maximal synergy and depth of thinking require an open, vibrant research environment in which people of all backgrounds thrive. We are passionately devoted to enhancing diversity and upholding uncompromised equity and anti-racism. These principles, along with the close proximity of BMG to other outstanding basic and clinical departments as well as several hospitals, vastly enhance our opportunities for collaboration and translation of paradigm-shifting basic discoveries to the clinic and beyond.
Proteolytic activation of human-specific Olduvai domains by the furin protease
Ashley Pacheco, Aaron Issaian, & Sikela & Hansen Labs with Vogeli Lab - January 2023 - Int J Biol Macromol
Structure and Formation of Z-DNA and Z-RNA
Jeffrey Krall, Parker Nichols, Morkos Henen, Quentin Vicens, & Beat Vogeli - January 2023 - Molecules
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells
Allison Porman Swain & Johnson Lab - November 2022 - PLoS Biol
Xrn2 substrate mapping identifies torpedo loading sites and extensive premature termination of RNA pol II transcription
Michael Cortazar & Bentley Lab - November 2022 - Genes & Dev.
The molecular mechanism of sialic acid transport mediated by Sialin
Wenxin Hu & Hongjin Zheng - January 2023 - Science Advances
Congratulations to all recent faculty, postdoc, and graduate student awardees!
![]() | March 2023 Dr. Cooper and her lab are highlighted in the new CUAnschutz “Possibilities Endless” marketing campaign. |
![]() | February 2023 Catherine Nicholas, Hesselberth Lab, received the NIH / NIDDK F31 award for "Characterizing molecular phenotypes of pancreatic islet reactive B cells in T1D through single cell sequencing". Congratulations! |
![]() | February 2023 Conner Langeberg, Kieft Lab, received the Poster Award at the 2023 Fusion Conference on Nucleic Acids. Congratulations! |
![]() | February 2023 Ning Zhao received an NIH R00 to study protein co-translational folding in living cells. Congratulations! |
![]() | January 2023 Travis Nemkov, D'Alessandro Lab, received a pilot grant from Golfers Against Cancer to use omics analysis for personalization of exercise prescription in lymphoma survivors. Congratulations! |
![]() | January 2023 Mohamed Ghoneim, Musselman Lab, has received an award from the CLC. Congratulations! |
![]() | January 2023 Michael Cortazar, Jagannathan Lab, has received an award from the AHA. Congratulations! |
![]() | December 2022 Quentin Vicens received an NIGMS grant award 1 R21GM148902-01, with Dr. Elena Rivas (Harvard University) as co-PI, title:"An all-in-one for RNA structure prediction using evolutionary information". Congratulations! |
![]() | December 2022 Vadym Zaberezhnyy, DeGregori Lab, has been awarded the 2022 Steven Fadul Award! Congratulations! |
![]() | November 2022 |
![]() | November 2022 Jay Hesselberth received a 2022 AB Nexus Award with Dr. Kostov (CU Boulder). |
November 2022 AML research by James DeGregori, Harry Park, and the DeGregori Lab was highlighted in CU Anschutz Today. | |
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