K12 IMPACT Update

January 2021


The K12 IMPACT (IMPlementation to Achieve Clinical Transformation) Program in dissemination and implementation science is a two-year career development program that prepares a diverse group of post-doctorate scholars for careers in T4 translational research with an emphasis on heart, lung, blood and sleep (HLBS) disorders.  Here, we highlight the work of one of our first-year scholars, Katy Trinkley, PharmD, PhD.  Dr. Trinkley is an Associate Professor in the Department of Clinical Pharmacy at the Skaggs School of Pharmacy and Pharmaceutical Sciences here on campus. As a primary care pharmacist and informaticist, Dr. Trinkley implements and evaluates clinical decision support solutions (CDS) within electronic health records across heterogeneous settings to optimize safe and effective prescribing for chronic cardiovascular disease.

In her research on clinical support solutions, Dr. Trinkley has found implementation science (IS) frameworks quite useful for understanding how to enhance the effectiveness and sustainability of CDS tools, as well as to help with generalization issues across different clinical settings and health systems.  In particular, Dr. Trinkley has employed the Practical Robust Implementation and Sustainability Model (PRISM) in conjunction with extant CDS design best practices to detect areas where the two methods could complement one another for a more thorough, helpful and integrated approach.  Her integration of PRISM and CDS best design practices has revealed five main phases that iteratively interact and inform each other: multilevel stakeholder engagement, designing the CDS, design and usability testing, thoughtful deployment, and performance evaluation.  The synthesis of the PRISM framework with CDS best practices into a single overarching approach enhances and extends user-centered design, better accounting for the multi-level, interactive and dynamic factors that contribute to the successful adoption, sustainability, and reproducibility of CDS implementations across clinical settings. A forthcoming publication describes findings from a randomized controlled trial that support the positive impact of this PRISM-based approach to CDS implementation.

Congratulations to Dr. Katy Trinkley on developing this roadmap for maximizing the successful rollout of CDS tools, not to mention furthering and substantiating the importance of the field of dissemination and implementation science!  To learn more about our scholars and the K12 IMPACT Program, please click HERE