We focus on epidemiological and clinical trials in the acute care setting, with a particular focus on early care of critically ill and injured patients. Our recent work incudes sepsis, respiratory failure, oxygenation strategies, and COVID-19. Our recent collaborations include the PETAL, SIREN, and IVY research networks. Our active projects are funded by NIH, DoD, and CDC.
Influenza Vaccine Effectiveness in the Critically Ill Network
Prevention and Early Treatment of Acute Lung Injury Network, funded by NHLBI. The goal of this application is to participate in the selection and conduct of clinical trials for the prevention and early treatment of acute lung injury across a network of 12 clinical centers. Our clinical center includes two academic and four community hospitals in the greater Denver area and a robust infrastructure for recruitment of critically ill emergency department and intensive care unit patients into clinical trials.
Trial of Early Antiviral Therapies during Non-hospitalized Outpatient Window (TREAT NOW) for COVID-19
Ginde AA, Talmor D; VIOLET Investigators and members of the National Heart, Lung, and Blood Institute PETAL Clinical Trials Network.
N Engl J Med. 2020 Apr 23;382(17):1670-1671. doi: 10.1056/NEJMc2000993. No abstract available.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Ginde AA, Brower RG, Caterino JM, Finck L, Banner-Goodspeed VM, Grissom CK, Hayden D, Hough CL, Hyzy RC, Khan A, Levitt JE, Park PK, Ringwood N, Rivers EP, Self WH, Shapiro NI, Thompson BT, Yealy DM, Talmor D.
N Engl J Med. 2019 Dec 26;381(26):2529-2540. doi: 10.1056/NEJMoa1911124. Epub 2019 Dec 11.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Moss M, Huang DT, Brower RG, Ferguson ND, Ginde AA, Gong MN, Grissom CK, Gundel S, Hayden D, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Khan A, Liu KD, Talmor D, Thompson BT, Ulysse CA, Yealy DM, Angus DC.
N Engl J Med. 2019 May 23;380(21):1997-2008. doi: 10.1056/NEJMoa1901686. Epub 2019 May 19.
Self WH, Semler MW, Bellomo R, Brown SM, deBoisblanc BP, Exline MC, Ginde AA, Grissom CK, Janz DR, Jones AE, Liu KD, Macdonald SPJ, Miller CD, Park PK, Reineck LA, Rice TW, Steingrub JS, Talmor D, Yealy DM, Douglas IS, Shapiro NI; CLOVERS Protocol Committee and NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network Investigators.
Ann Emerg Med. 2018 Oct;72(4):457-466. doi: 10.1016/j.annemergmed.2018.03.039. Epub 2018 May 10.
Systematic review of oxygenation and clinical outcomes to inform oxygen targets in critically ill trauma patients.
Douin DJ, Schauer SG, Anderson EL, Jones J, DeSanto K, Cunningham CW, Bebarta VS, Ginde AA. J Trauma Acute Care Surg. 2019 Oct;87(4):961-977. doi: 10.1097/TA.0000000000002392.PMID: 31162333
A single-site pilot implementation of a novel trauma training program for prehospital providers in a resource-limited setting.
Mould-Millman NK, Dixon J, Lamp A, de Vries S, Beaty B, Finck L, Colborn K, Moodley K, Skenadore A, Glasgow RE, Havranek EP, Bebarta VS, Ginde AA. Pilot Feasibility Stud. 2019 Dec 5;5:143. doi: 10.1186/s40814-019-0536-0. eCollection 2019.PMID: 31844551
Rhodes WC, Hertner G, Price R, Finck L, Temmer C, Cushing T, Flarity K.
Mil Med. 2017 Jul;182(7):e1718-e1721. doi: 10.7205/MILMED-D-16-00386.
Jones Rhodes W, Steinbruner D, Finck L, Flarity K.
Prehosp Emerg Care. 2016 Nov-Dec;20(6):792-797. Epub 2016 Jul 13.
Erin Anderson, RN
Senior Professional Research Assistant
Jill Bastman, BSN, RN
Jessica Cwik, BA
David Huynh, BA
Conner Jackson, MS
Amanda Martinez, MPH
Flora Martinez, MPH, RN
Jennifer Peers, BSN, RN
Professional Research Assistant
John Rice, PhD
Cori Withers, BS