ACT V: This is a phase 3b , randomized, double-blind, placebo-controlled, parallel group, multi-center, multinational safety and efficacy study in which subjects are eligible for enrollment if their atrial fibriliation is determined by the investigator to be best managed by acute conversion to sinus rhythm, and have recent onset  of, symptomatic atrial fibrillation and on evidence or history of congestive heart failure. 

Evaluation of Sarcoidosis: The purpose of the study is to investigate the methods for diagnosing the presence of cardiac sarcoid and to evaluate the efficacy of the implantable cardioverter defibrillator in patients with present evidence of cardiac sarcoid for the prevention of sudden cardiac death.

AdviseCRT: The purpose of this study is to test the possibility of determining the change in the amount of blood pumped from the heart in one beat by measuring the electrical resistance between two points in the heart with an experimental recording system.
AdaptiveCRT: The purpose of this study is to determine if Cardiac Resynchronization Therapy (CRT), may be beneficial for subjects that are experiencing a decrease in the pumping ability in their heart.  A new feature called Adaptive CRT (aCRT) that attempts to automatically optimize CRT in subjects’ CRT D devices.  The aCRT feature observes patterns in your heart’s contractions and then automatically adjusts your CRT D device to optimize CRT for you without echo testing.

EchoCRT: The purpose of this study is to evaluate the effects of Cardiac Resynchronization Therapy (CRT) on mortality and morbidity of subjects with heart failure due to left ventricular systolic dysfunction already receiving current standard heart failure pharmacological therapy.

Envision: The purpose of this study is to demonstrate that Cardiac Resynchronization Therapy (CRT) responder rate can be improved by 3D echo-guided left ventricular lead placement compared to traditional LV lead placement.

Vest/Predicts: The purpose of this study is to learn more about how to predict arrhythmias after a heart attack.