The core offers a wide variety of pre-clinical models in rats and mice, from development to analysis.
Our main therapeutic areas are cardiovascular, renal, and pulmonary. We utilize state-of-the-art data acquisition platforms, and offer a comprehensive suite of research services ranging from pharmacokinetics, target-based functional screens through model validation, and complex proof-of-concept studies.
Thoracic Aorta Constriction (TAC)
Left Anterior Coronary Artery Ligation (MI)
Unilateral and 5/6 Nephrectomy
Pulmonary Artery Ligation
LV-RV Pressure Volume Loops
Pulmonary Arterial Pressure
Ejection Fraction/Fractional Shortening
LV Dimensions and Wall Thickness
Cardiac Output/Stroke Volume
Pulmonary Vein Blood Flow
Mitral Valve Blood Flow (E/A)
Mitral Valve Tissue Movement (E'/A')