The core offers a wide variety of pre-clinical models in rats and mice, from development to analysis.
Our main therapeutic areas are cardiovascular, renal, and pulmonary. We utilize state-of-the-art data acquisition platforms, and offer a comprehensive suite of research services ranging from pharmacokinetics, target-based functional screens through model validation, and complex proof-of-concept studies.
Small Animal Ultrasound
Cardiac Imaging
3D Imaging
Vasculature Imaging
Tumor Imaging
Ultrasound-guided Injections
Contrast Imaging
Thoracic Imaging
Small Animal Surgery
Thoracic Aorta Constriction (TAC)
Left Anterior Coronary Artery Ligation (MI)
Unilateral and 5/6 Nephrectomy
Pulmonary Artery Ligation
Small Animal Catheterization
LV-RV Pressure Volume Loops
Pulmonary Arterial Pressure
Systolic Function
Ejection Fraction/Fractional Shortening
LV Dimensions and Wall Thickness
Cardiac Output/Stroke Volume
Diastolic Function
Pulmonary Vein Blood Flow
Mitral Valve Blood Flow (E/A)
Mitral Valve Tissue Movement (E'/A')
Hypertension
Pulmonary Vein Blood Flow/DiameterRV Wall Thickness
Tricuspid Valve Blood Flow
The Vevo® platform was the world’s first commercially available high-frequency array based ultrasound imaging system and has since emerged as the gold standard in small animal anatomical and functional in vivo imaging. The Vevo Family of high-frequency ultrasound products enables the researcher to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, in real-time and with a resolution down to 30 µm. For more information on pricing and scheduling, please contact Maria Cavasin at
maria.cavasin@ucdenver.edu
303-724-5424.
maria.cavasin@ucdenver.edu
303-724-5424.