Biophysics Shared Resource Facility
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The Biophysics Shared Resource Facility provides shared instrumentation, expert consultation, and user training for rigorous biophysical and biochemical characterization of biomolecular systems. The facility helps investigators select appropriate methods, design experiments, collect high-quality data, troubleshoot assays, and analyze and interpret results.
The Core supports binding and interaction analysis, thermodynamic measurements, structural and conformational characterization, macromolecular assembly and sample-quality assessment, and single-molecule force and fluorescence spectroscopy. Assisted-use and trained-user self-service workflows are available depending on the instrument, project, and user experience.
Prospective users are encouraged to contact the Facility Manager for an initial consultation before scheduling experiments or training.
Current list of instrumentation
- Beckman Coulter XL-I - Analytical Ultracentrifugation (AUC)
- MicroCal iTC200 - Isothermal Titration Calorimetry (ITC)
- JASCO J-815 - Circular Dichroism, Absorbance, and Optical Rotary Dispersion (CD/ORD)
- Horiba FluoroMax-3/FM3 and Fluorolog 2 - Fluorescence Spectroscopy
- NanoTemper Monolith NT.115 Pico - Microscale Thermophoresis (MST)
- Wyatt DynaPro Plate Reader III - Dynamic Light Scattering (DLS)
- Cytiva Biacore T200 - Surface Plasmon Resonance (SPR)
- Refeyn TwoMP - Mass Photometry
- LUMICKS C-Trap Dymo-400 - Quad Optical Tweezers, Three-Color Confocal Fluorescence, and Microfluidics
- Stratagene Mx3000P - Quantitative Real-Time PCR (qPCR)
Contact and location
Dr. Robb Welty - Facility Manager
Email: [email protected]
Phone: 303-724-3322
University of Colorado School of Medicine, Research 1 South, L18-1308, 12801 E. 17th Ave., Aurora, CO 80045
Standard staffed hours: 9:00 AM-5:00 PM, Monday-Friday
This facility is supported in part by the University of Colorado School of Medicine.
Facility Leadership
Biophysics Core Facility
University of Colorado School of Medicine
Research 1 South
L18-1308
12801 E. 17th Ave.
Aurora, CO 80045