Abdelazeem, K. N. M., Nguyen, D., Corbo, S., Darragh, L. B., Matsumoto, M. W., Van Court, B., Neupert, B., Yu, J., Olimpo, N. A., Osborne, D. G., Gadwa, J., Ross, R. B., Nguyen, A., Bhatia, S., Kapoor, M., Friedman, R. S., Jacobelli, J., Saviola, A. J., Knitz, M. W., … Karam, S. D. (2025). Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC. Oncogene, 44(3), 130–146. https://doi.org/10.1038/s41388-024-03208-9
Borja, M., Castañeda-Gaytán, G., Alagón, A., Strickland, J. L., Parkinson, C. L., Gutiérrez-Martínez, A., Rodriguez-López, B., Zarzosa, V., Lomonte, B., Saviola, A. J., Fernández, J., Smith, C. F., Hansen, K. C., Pérez-Robles, A., Castañeda-Pérez, S., Hirst, S. R., Olvera-Rodríguez, F., Fernández-Badillo, L., Sigala, J., … Neri-Castro, E. (2025). Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP, 290, 110129. https://doi.org/10.1016/j.cbpc.2025.110129
Cendali, F. I., Lisk, C., Dzieciatkowska, M., LaCroix, I. S., Reisz, J. A., Harral, J., Stephenson, D., Hay, A. M., Wartchow, E. P., Darehshouri, A., Dziewulska-Cronk, K. H., Buehler, P. W., Norris, P. J., Deng, X., Busch, M. P., Earley, E. J., Page, G. P., Hansen, K. C., Zimring, J. C., … D’Alessandro, A. (2025). Increased exercise tolerance in humanized G6PD-deficient mice. Blood Advances, 9(2), 321–334. https://doi.org/10.1182/bloodadvances.2024013968
Chakraborty, N., Momirov, J., Radakovic, A., Chatterjee, S., Kirchhoff, A. M., Kolb, A.-L., West, T. J., Sanchez, B. B., Martinez-Bartolome, S., Saviola, A., McClatchy, D., Yates, J. R. 3rd, Chen, J. S., Lairson, L. L., Felding, B. H., & Boger, D. L. (2025). Insights into Free Drug Release from Efficacious N-Acyl O-Aminophenol Duocarmycin Prodrugs. ACS Chemical Biology. https://doi.org/10.1021/acschembio.4c00754
D’Alessandro, A., Keele, G. R., Hay, A., Nemkov, T., Earley, E. J., Stephenson, D., Vincent, M., Deng, X., Stone, M., Dzieciatkowska, M., Hansen, K. C., Kleinman, S., Spitalnik, S. L., Roubinian, N., Norris, P. J., Busch, M. P., Page, G. P., Stockwell, B. R., Churchill, G. A., & Zimring, J. C. (2025). Ferroptosis regulates hemolysis in stored murine and human red blood cells. Blood, 145(7), 765–783. https://doi.org/10.1182/blood.2024026109
Darula, Z., McCabe, M. C., Barrett, A., Schmitt, L. R., Maslanka, M. D., Saviola, A. J., Orgel, J., Burlingame, A., Staab-Weijnitz, C. A., Stenmark, K., Weaver, V., Chalkley, R. J., & Hansen, K. C. (2024). Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry. https://doi.org/10.1101/2024.03.31.587441
Gadwa, J., Yu, J., Piper, M., Knitz, M. W., Darragh, L. B., Olimpo, N., Corbo, S., Beynor, J. I., Neupert, B., Nguyen, A. T., Hodgson, C., Nguyen, D., Abdelazeem, K. N., Saviola, A., Pousse, L., Bransi, A., Pincha, M., Klein, C., Amann, M., & Karam, S. D. (2025). Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment. Journal for Immunotherapy of Cancer, 13(1). https://doi.org/10.1136/jitc-2024-010405
Key, A. M., Earley, E. J., Tzounakas, V. L., Anastasiadi, A. T., Nemkov, T., Stephenson, D., Dzieciatkowska, M., Reisz, J. A., Keele, G. R., Deng, X., Stone, M., Kleinman, S., Hansen, K. C., Norris, P. J., Busch, M. P., Roubinian, N. H., Page, G. P., & D’Alessandro, A. (2025). Red blood cell urate levels are linked to hemolysis in vitro and post-transfusion as a function of donor sex, population and genetic polymorphisms in SLC2A9 and ABCG2. Transfusion. https://doi.org/10.1111/trf.18140
Lee, E., Saviola, A., Bevers, S., Redzic, J. S., Maroney, S. P., Shaw, S., Tamkin, E., Fulte, S., Nemkov, T., Meyer, N., D’Alessandro, A., Hansen, K. C., Clark, S. E., & Eisenmesser, E. (2025). Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. Protein Science : A Publication of the Protein Society, 34(1), e5253. https://doi.org/10.1002/pro.5253
Puiggalí-Jou, A., Hui, I., Baldi, L., Frischknecht, R., Asadikorayem, M., Janiak, J., Chansoria, P., McCabe, M. C., Stoddart, M. J., Hansen, K. C., Christman, K. L., & Zenobi-Wong, M. (2025). Biofabrication of anisotropic articular cartilage based on decellularized extracellular matrix. Biofabrication, 17(1). https://doi.org/10.1088/1758-5090/ad9cc2
Reisz, J. A., Earley, E. J., Nemkov, T., Key, A., Stephenson, D., Keele, G. R., Dzieciatkowska, M., Spitalnik, S. L., Hod, E. A., Kleinman, S., Roubinian, N. H., Gladwin, M. T., Hansen, K. C., Norris, P. J., Busch, M. P., Zimring, J. C., Churchill, G. A., Page, G. P., & D’Alessandro, A. (2025). Arginine metabolism is a biomarker of red blood cell and human aging. Aging Cell, 24(2), e14388. https://doi.org/10.1111/acel.14388
Reitsma, S. E., Barsoum, J. R., Hansen, K. C., Sassin, A. M., Dzieciatkowska, M., James, A. H., Aagaard, K. M., Ahmadzia, H. K., & Wolberg, A. S. (2025). Agnostic identification of plasma biomarkers for postpartum hemorrhage risk. American Journal of Obstetrics and Gynecology, 232(2), 220.e1-220.e18. https://doi.org/10.1016/j.ajog.2024.04.050
Sieh, L., Peasley, E., Mao, E., Mitchell, A., Heinonen, G., Ghoshal, S., Agarwal, S., Park, S., Connolly, E. S., Claassen, J., Moore, E. E., Hansen, K., Hod, E. A., Francis, R. O., & Roh, D. J. (2025). Admission Viscoelastic Hemostatic Assay Parameters Predict Poor Long-Term Intracerebral Hemorrhage Outcomes. Neurocritical Care, 42(1), 100–107. https://doi.org/10.1007/s12028-024-02051-w
Thielen, O., Stafford, P., Debot, M., Kelher, M., Mitra, S., Hallas, W., Gallagher, L. T., Schaid, T., Stocker, B., Ramser, B., D’Alessandro, A., Hansen, K., Silliman, C. C., Moore, E., Mosnier, L., Griffin, J., & Cohen, M. (2025). Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma. The Journal of Trauma and Acute Care Surgery, 98(1), 94–100. https://doi.org/10.1097/TA.0000000000004406
Bamberg, E. E., Maslanka, M., Vinod-Paul, K., Sams, S., Pollack, E., Conklin, M., Kabos, P., & Hansen, K. C. (2024). Obesity-driven changes in breast tissue exhibit a pro-angiogenic extracellular matrix signature. Matrix Biology Plus, 24, 100162. https://doi.org/10.1016/j.mbplus.2024.100162
Bartlett, K. E., Hall, S. R., Rasmussen, S. A., Crittenden, E., Dawson, C. A., Albulescu, L.-O., Laprade, W., Harrison, R. A., Saviola, A. J., Modahl, C. M., Jenkins, T. P., Wilkinson, M. C., Gutiérrez, J. M., & Casewell, N. R. (2024). Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib. Proceedings of the National Academy of Sciences of the United States of America, 121(19), e2315597121. https://doi.org/10.1073/pnas.2315597121
Brechbuhl, H. M., Han, A., Paul, K. V., Nemkov, T., Ramachandran, S., Ward, A., Jacobsen, B. M., Hansen, K., Sartorius, C. A., D’Alessandro, A., & Kabos, P. (2024). Metabolic Switch in Endocrine Resistant Estrogen Receptor Positive Breast Cancer. https://doi.org/10.1101/2024.12.28.630631
Calvete, J. J., Lomonte, B., Saviola, A. J., Calderón Celis, F., & Ruiz Encinar, J. (2024). Quantification of snake venom proteomes by mass spectrometry-considerations and perspectives. Mass Spectrometry Reviews, 43(5), 977–997. https://doi.org/10.1002/mas.21850
Chalivendra, S., Shi, S., Li, X., Kuang, Z., Giovinazzo, J., Zhang, L., Rossi, J., Wang, J., Saviola, A. J., Welty, R., Liu, S., Vaeth, K. F., Zhou, Z. H., Hansen, K. C., Taliaferro, J. M., & Zhao, R. (2024). Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. RNA (New York, N.Y.), 30(8), 1070–1088. https://doi.org/10.1261/rna.079917.123
Cleland, N. R. W., Potter, G. J., Buck, C., Quang, D., Oldham, D., Neal, M., Saviola, A., Niemeyer, C. S., Dobrinskikh, E., & Bruce, K. D. (2024). Altered metabolism and DAM-signatures in female brains and microglia with aging. Brain Research, 1829, 148772. https://doi.org/10.1016/j.brainres.2024.148772
Corbo, S., Nguyen, D., Bhatia, S., Darragh, L. B., Abdelazeem, K. N. M., Court, B. V., Olimpo, N. A., Gadwa, J., Yu, J., Hodgson, C., Samedi, V., Garcia, E. S., Siu, L., Saviola, A., Heasley, L. E., Knitz, M. W., Pasquale, E. B., & Karam, S. D. (2024). The pro-tumoral and anti-tumoral roles of EphA4 on T regulatory cells and tumor associated macrophages during HNSCC tumor progression. https://doi.org/10.1101/2024.08.13.607778
Cralley, A. L., Moore, E. E., LaCroix, I., Schaid, T. J., Thielen, O., Hallas, W., Hom, P., Mitra, S., Kelher, M., Hansen, K., Cohen, M., Silliman, C., Sauaia, A., & Fox, C. J. (2024). RESUSCITATIVE ENDOVASCULAR BALLOON OCCLUSION OF THE AORTA: ZONE 1 REPERFUSION-INDUCED COAGULOPATHY. Shock (Augusta, Ga.), 61(2), 322–329. https://doi.org/10.1097/SHK.0000000000002299
D’Alessandro, A., Earley, E. J., Nemkov, T., Stephenson, D., Dzieciatkowska, M., Hansen, K. C., Minetti, G., Champigneulle, B., Stauffer, E., Pichon, A., Furian, M., Verges, S., Kleinman, S., Norris, P. J., Busch, M. P., Page, G. P., & Kaestner, L. (2024). Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude. Proceedings of the National Academy of Sciences of the United States of America, 121(1), e2315930120. https://doi.org/10.1073/pnas.2315930120
Darragh, L. B., Nguyen, A., Pham, T. T., Idlett-Ali, S., Knitz, M. W., Gadwa, J., Bukkapatnam, S., Corbo, S., Olimpo, N. A., Nguyen, D., Van Court, B., Neupert, B., Yu, J., Ross, R. B., Corbisiero, M., Abdelazeem, K. N. M., Maroney, S. P., Galindo, D. C., Mukdad, L., … Karam, S. D. (2024). Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs. Med (New York, N.Y.), 5(3), 254-270.e8. https://doi.org/10.1016/j.medj.2024.02.002
Darula, Z., McCabe, M. C., Barrett, A., Schmitt, L. R., Maslanka, M. D., Saviola, A. J., Orgel, J., Burlingame, A., Staab-Weijnitz, C. A., Stenmark, K., Weaver, V., Chalkley, R. J., & Hansen, K. C. (2024). Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry. https://doi.org/10.1101/2024.03.31.587441
Gopalan, S. S., Perry, B. W., Francioli, Y. Z., Schield, D. R., Guss, H. D., Bernstein, J. M., Ballard, K., Smith, C. F., Saviola, A. J., Adams, R. H., Mackessy, S. P., & Castoe, T. A. (2024). Diverse Gene Regulatory Mechanisms Alter Rattlesnake Venom Gene Expression at Fine Evolutionary Scales. Genome Biology and Evolution, 16(7). https://doi.org/10.1093/gbe/evae110
Kheyfets, V. O., Sweatt, A. J., Zhang, H., Nemkov, T., Heerdt, P., Dzieciatkowska, M., Stephenson, D., LaCroix, I. S., D’Alessandro, A., Oldham, W. M., Hansen, K., Zamanian, R. T., & Stenmark, K. R. (2024). Identification of candidate biomarkers and molecular networks associated with Pulmonary Arterial Hypertension using machine learning and plasma multi-Omics analysis. In medRxiv: The preprint server for health sciences (p. 2024.12.17.24319117). https://doi.org/10.1101/2024.12.17.24319117
Kotz, J., Martz, E. J., Nelson, M., Savoie, N., Schmitt, L., States, J., Holton, N., Hansen, K., & Johnson, A. M. (2024). Novel interactions within the silent information regulator heterochromatin complex potentiate inter-subunit communication and gene repression. https://doi.org/10.1101/2024.12.23.630195
LaCroix, I. S., Moore, E. E., Cralley, A., Cendali, F. I., Dzieciatkowska, M., Hom, P., Mitra, S., Cohen, M., Silliman, C., Hansen, K. C., & D’Alessandro, A. (2024). Multiomics Signatures of Coagulopathy in a Polytrauma Swine Model Contrasted with Severe Multisystem Injured Patients. Journal of Proteome Research, 23(4), 1163–1173. https://doi.org/10.1021/acs.jproteome.3c00581
Laklai, H., Miroshnikova, Y. A., Pickup, M. W., Collisson, E. A., Kim, G. E., Barrett, A. S., Hill, R. C., Lakins, J. N., Schlaepfer, D. D., Mouw, J. K., LeBleu, V. S., Roy, N., Novitskiy, S. V., Johansen, J. S., Poli, V., Kalluri, R., Iacobuzio-Donahue, C. A., Wood, L. D., Hebrok, M., … Weaver, V. M. (2024). Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine, 30(3), 908. https://doi.org/10.1038/s41591-023-02694-w
McCabe, M. C., Saviola, A. J., & Hansen, K. C. (2024). Compartment-Resolved Proteomics with Deep Extracellular Matrix Coverage. Bio-Protocol, 14(23), e5123. https://doi.org/10.21769/BioProtoc.5123
Nemkov, T., Cendali, F., Dzieciatkowska, M., Stephenson, D., Hansen, K. C., Jankowski, C. M., D’Alessandro, A., & Marker, R. J. (2024). A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series. Pathophysiology : The Official Journal of the International Society for Pathophysiology, 31(1), 166–182. https://doi.org/10.3390/pathophysiology31010013
Nemkov, T., Key, A., Stephenson, D., Earley, E. J., Keele, G. R., Hay, A., Amireault, P., Casimir, M., Dussiot, M., Dzieciatkowska, M., Reisz, J. A., Deng, X., Stone, M., Kleinman, S., Spitalnik, S. L., Hansen, K. C., Norris, P. J., Churchill, G. A., Busch, M. P., … D’Alessandro, A. (2024). Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro. Blood, 143(24), 2517–2533. https://doi.org/10.1182/blood.2024023983
Nemkov, T., Stephenson, D., Earley, E. J., Keele, G. R., Hay, A., Key, A., Haiman, Z., Erickson, C., Dzieciatkowska, M., Reisz, J. A., Moore, A., Stone, M., Deng, X., Kleinman, S., Spitalnik, S. L., Hod, E. A., Hudson, K. E., Hansen, K. C., Palsson, B. O., … D’Alessandro, A. (2024). Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes. https://doi.org/10.1101/2023.09.11.557250
Nemkov, T., Stephenson, D., Erickson, C., Dzieciatkowska, M., Key, A., Moore, A., Earley, E. J., Page, G. P., Lacroix, I. S., Stone, M., Deng, X., Raife, T., Kleinman, S., Zimring, J. C., Roubinian, N., Hansen, K. C., Busch, M. P., Norris, P. J., & D’Alessandro, A. (2024). Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo. Blood, 143(5), 456–472. https://doi.org/10.1182/blood.2023022052
Niemeyer, C. S., Frietze, S., Coughlan, C., Lewis, S. W. R., Bustos Lopez, S., Saviola, A. J., Hansen, K. C., Medina, E. M., Hassell, J. E. J., Kogut, S., Traina-Dorge, V., Nagel, M. A., Bruce, K. D., Restrepo, D., Mahalingam, R., & Bubak, A. N. (2024). Suppression of the host antiviral response by non-infectious varicella zoster virus extracellular vesicles. Journal of Virology, 98(8), e0084824. https://doi.org/10.1128/jvi.00848-24
Pham-Danis, C., Chia, S. B., Scarborough, H. A., Danis, E., Nemkov, T., Kleczko, E. K., Navarro, A., Goodspeed, A., Bonney, E. A., Dinarello, C. A., Marchetti, C., Nemenoff, R. A., Hansen, K., & DeGregori, J. (2024). Inflammation promotes aging-associated oncogenesis in the lung. https://doi.org/10.1101/2024.03.01.583044
Piper, M., Gadwa, J., Hodgson, C., Knitz, M., Yee, E., Zhu, Y., Larson, K. Y., Klein, C., Amann, M., Saviola, A., & Karam, S. D. (2024). IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells. https://doi.org/10.1101/2024.09.18.613691
Ross, R. B., Gadwa, J., Yu, J., Darragh, L. B., Knitz, M. W., Nguyen, D., Olimpo, N. A., Abdelazeem, K. N. M., Nguyen, A., Corbo, S., Van Court, B., Beynor, J., Neupert, B., Saviola, A. J., D’Alessandro, A., & Karam, S. D. (2024). PPARα Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in Counteraction. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 30(9), 1916–1933. https://doi.org/10.1158/1078-0432.CCR-23-3433
Smith, C. F., Modahl, C. M., Ceja Galindo, D., Larson, K. Y., Maroney, S. P., Bahrabadi, L., Brandehoff, N. P., Perry, B. W., McCabe, M. C., Petras, D., Lomonte, B., Calvete, J. J., Castoe, T. A., Mackessy, S. P., Hansen, K. C., & Saviola, A. J. (2024). Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling. Molecular & Cellular Proteomics : MCP, 23(6), 100779. https://doi.org/10.1016/j.mcpro.2024.100779
Stincone, P., Naimi, A., Saviola, A. J., Reher, R., & Petras, D. (2024). Decoding the molecular interplay in the central dogma: An overview of mass spectrometry-based methods to investigate protein-metabolite interactions. Proteomics, 24(12–13), e2200533. https://doi.org/10.1002/pmic.202200533
Stocker, B. W., LaCroix, I. S., Erickson, C., Gallagher, L. T., Ramser, B. J., Thielen, O., Hallas, W., Mitra, S., Moore, E. E., Hansen, K., D’Alessandro, A., Silliman, C. C., & Cohen, M. J. (2024). Trauma patients with type O blood exhibit unique multiomics signature with decreased lectin pathway of complement levels. The Journal of Trauma and Acute Care Surgery, 97(5), 753–763. https://doi.org/10.1097/TA.0000000000004367
Sun, Q., Chen, W., Wu, R., Tao, B., Wang, P., Sun, B., Alvarez, J. F., Ma, F., Galindo, D. C., Maroney, S. P., Saviola, A. J., Hansen, K. C., Li, S., & Deb, A. (2024). Serine protease inhibitor, SerpinA3n, regulates cardiac remodelling after myocardial infarction. Cardiovascular Research, 120(8), 943–953. https://doi.org/10.1093/cvr/cvae075
Thielen, O., Mitra, S., Debot, M., Schaid, T., Hallas, W., Gallagher, L. T., Erickson, C., Cralley, A., Stafford, P., Silliman, C., D’Alessandro, A., Hansen, K., Sauaia, A., Moore, E., Mosnier, L., Griffin, J., & Cohen, M. (2024). Mitigation of trauma-induced endotheliopathy by activated protein C: A potential therapeutic for postinjury thromboinflammation. The Journal of Trauma and Acute Care Surgery, 96(1), 116–122. https://doi.org/10.1097/TA.0000000000004142
Upadhyay, V., Ray, S., Panja, S., Saviola, A. J., Maluf, N. K., & Mallela, K. M. G. (2024). Biophysical characterization of the dystrophin C-terminal domain: Dystrophin interacts differentially with dystrobrevin isoforms. The Journal of Biological Chemistry, 300(12), 108002. https://doi.org/10.1016/j.jbc.2024.108002
Van Court, B., Ciccaglione, M., Neupert, B., Knitz, M. W., Maroney, S. P., Nguyen, D., Abdelazeem, K. N. M., Exner, A. A., Saviola, A. J., Benninger, R. K. P., & Karam, S. D. (2024). Heterogeneous Kinetics of Nanobubble Ultrasound Contrast Agent and Angiogenic Signaling in Head and Neck Cancer. https://doi.org/10.1101/2024.09.22.614362
Williams, J., Iheagwam, F. N., Maroney, S. P., Schmitt, L. R., Brown, R. D., Krafsur, G. M., Frid, M. G., McCabe, M. C., Gandjeva, A., Williams, K. J., Luyendyk, J. P., Saviola, A. J., Tuder, R. M., Stenmark, K., & Hansen, K. C. (2024). A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation. American Journal of Physiology. Cell Physiology, 327(6), C1666–C1680. https://doi.org/10.1152/ajpcell.00274.2024
Yu, J., Gadwa, J., Ross, R. B., Knitz, M., Darragh, L. B., Abdelazeem, K. N. M., Beynor, J., Neupert, B., Nguyen, A., Nguyen, D., Olimpo, N., Corbo, S., Van Court, B., D’Alessandro, A., Saviola, A., & Karam, S. D. (2024). IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models. Cancer Immunology, Immunotherapy : CII, 73(5), 90. https://doi.org/10.1007/s00262-024-03664-y
Bolf, E. L., Beadnell, T. C., Rose, M. M., D’Alessandro, A., Nemkov, T., Hansen, K. C., & Schweppe, R. E. (2023). Dasatinib and Trametinib Promote Anti-Tumor Metabolic Activity. Cells, 12(10). https://doi.org/10.3390/cells12101374
Bowers, S. L. K., Meng, Q., Kuwabara, Y., Huo, J., Minerath, R., York, A. J., Sargent, M. A., Prasad, V., Saviola, A. J., Galindo, D. C., Hansen, K. C., Vagnozzi, R. J., Yutzey, K. E., & Molkentin, J. D. (2023). Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics. Cells, 12(17), Article 17. https://doi.org/10.3390/cells12172174
Brown, R. D., Hunter, K. S., Li, M., Frid, M. G., Harral, J., Krafsur, G. M., Holt, T. N., Williams, J., Zhang, H., Riddle, S. R., Edwards, M. G., Kumar, S., Hu, C.-J., Graham, B. B., Walker, L. A., Garry, F. B., Buttrick, P. M., Lahm, T., Kheyfets, V. O., … Stenmark, K. R. (2023). Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model. American Journal of Physiology. Heart and Circulatory Physiology, 324(6), H804–H820. https://doi.org/10.1152/ajpheart.00614.2022
Bubak, A. N., Coughlan, C., Posey, J., Saviola, A. J., Niemeyer, C. S., Lewis, S. W. R., Lopez, S. B., Solano, A., Tyring, S. K., Delaney, C., Neeves, K. B., Mahalingam, R., Hansen, K. C., & Nagel, M. A. (2023). Zoster-Associated Prothrombotic Plasma Exosomes and Increased Stroke Risk. The Journal of Infectious Diseases, 227(8), 993–1001. https://doi.org/10.1093/infdis/jiac405
Cohen, M. J., Erickson, C. B., Lacroix, I. S., Debot, M., Dzieciatkowska, M., Schaid, T. R., Hallas, M. W., Thielen, O. N., Cralley, A. L., Banerjee, A., Moore, E. E., Silliman, C. C., D’Alessandro, A., & Hansen, K. C. (2023). Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients. In bioRxiv: The preprint server for biology (p. 2023.08.16.553446). https://doi.org/10.1101/2023.08.16.553446
Cralley, A. L., Erickson, C., Schaid, T. R. J., Hallas, W., Thielen, O., Mitra, S., Stafford, P., Hom, P., Silliman, C., Cohen, M. J., Moore, E. E., D’Alessandro, A., & Hansen, K. C. (2023). The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury. American Journal of Surgery, S0002-9610(23)00374-4. https://doi.org/10.1016/j.amjsurg.2023.07.040
De Man, R., McDonough, J. E., Adams, T. S., Manning, E. P., Myers, G., Vos, R., Ceulemans, L., Dupont, L., Vanaudenaerde, B. M., Wuyts, W. A., Rosas, I. O., Hagood, J. S., Ambalavanan, N., Niklason, L., Hansen, K. C., Yan, X., & Kaminski, N. (2023). A Multi-omic Analysis of the Human Lung Reveals Distinct Cell Specific Aging and Senescence Molecular Programs. In bioRxiv: The preprint server for biology (p. 2023.04.19.536722). https://doi.org/10.1101/2023.04.19.536722
Duran, P., Boscolo Sesillo, F., Cook, M., Burnett, L., Menefee, S. A., Do, E., French, S., Zazueta-Damian, G., Dzieciatkowska, M., Saviola, A. J., Shah, M. M., Sanvictores, C., Osborn, K. G., Hansen, K. C., Shtrahman, M., Christman, K. L., & Alperin, M. (2023). Proregenerative extracellular matrix hydrogel mitigates pathological alterations of pelvic skeletal muscles after birth injury. Science Translational Medicine, 15(707), eabj3138. https://doi.org/10.1126/scitranslmed.abj3138
Gadwa, J., Amann, M., Bickett, T. E., Knitz, M. W., Darragh, L. B., Piper, M., Van Court, B., Bukkapatnam, S., Pham, T. T., Wang, X.-J., Saviola, A. J., Deak, L. C., Umaña, P., Klein, C., D’Alessandro, A., & Karam, S. D. (2023). Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC. Cell Reports Medicine, 4(8), 101150. https://doi.org/10.1016/j.xcrm.2023.101150
Grabowsky, E. R., Saviola, A. J., Alvarado-Díaz, J., Mascareñas, A. Q., Hansen, K. C., Yates, J. R. 3rd, & Mackessy, S. P. (2023). Montane Rattlesnakes in México: Venoms of Crotalus tancitarensis and Related Species within the Crotalus intermedius Group. Toxins, 15(1). https://doi.org/10.3390/toxins15010072
Han, D. S., Erickson, C., Hansen, K. C., Kirkbride-Romeo, L., He, Z., Rodell, C. B., & Soranno, D. E. (2023). Mesenchymal Stem Cells Delivered Locally to Ischemia-Reperfused Kidneys via Injectable Hyaluronic Acid Hydrogels Decrease Extracellular Matrix Remodeling 1 Month after Injury in Male Mice. Cells, 12(13). https://doi.org/10.3390/cells12131771
LaCroix, I. S., Cralley, A., Moore, E. E., Cendali, F. I., Dzieciatkowska, M., Hom, P., Mitra, S., Cohen, M., Silliman, C., Sauaia, A., Hansen, K. C., & D’Alessandro, A. (2023). Omics Signatures of Tissue Injury and Hemorrhagic Shock in Swine. Annals of Surgery. https://doi.org/10.1097/SLA.0000000000005944
Lee, E., Redzic, J. S., Saviola, A. J., Li, X., Ebmeier, C. C., Kutateladze, T., Hansen, K. C., Zhao, R., Ahn, N., Sluchanko, N. N., & Eisenmesser, E. (2023). Molecular insight into the specific interactions of the SARS-Coronavirus-2 nucleocapsid with RNA and host protein. Protein Science : A Publication of the Protein Society, 32(4), e4603. https://doi.org/10.1002/pro.4603
McCabe, M. C., Gejji, V., Barnebey, A., Siuzdak, G., Hoang, L. T., Pham, T., Larson, K. Y., Saviola, A. J., Yannone, S. M., & Hansen, K. C. (2023). From volcanoes to the bench: Advantages of novel hyperthermoacidic archaeal proteases for proteomics workflows. Journal of Proteomics, 289, 104992. https://doi.org/10.1016/j.jprot.2023.104992
McCabe, M. C., Saviola, A. J., & Hansen, K. C. (2023). Mass Spectrometry-Based Atlas of Extracellular Matrix Proteins across 25 Mouse Organs. Journal of Proteome Research, 22(3), 790–801. https://doi.org/10.1021/acs.jproteome.2c00526
McCourt, J. L., Stearns-Reider, K. M., Mamsa, H., Kannan, P., Afsharinia, M. H., Shu, C., Gibbs, E. M., Shin, K. M., Kurmangaliyev, Y. Z., Schmitt, L. R., Hansen, K. C., & Crosbie, R. H. (2023). Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways. Skeletal Muscle, 13(1), 1. https://doi.org/10.1186/s13395-022-00311-x
Pei, M., Pei, Y. A., Zhou, S., Mikaeiliagah, E., Erickson, C., Giertych, B., Akhter, H., Wang, L., Stewart, A., Parenti, J., Wang, B., Wen, S., Sim, S., Quenneville, E., Hansen, K. C., Frisch, S., & Hu, G. (2023). Matrix from urine stem cells boosts tissue-specific stem cell mediated functional cartilage reconstruction. Bioactive Materials, 23, 353–367. https://doi.org/10.1016/j.bioactmat.2022.11.012
Piper, M., Hoen, M., Darragh, L. B., Knitz, M. W., Nguyen, D., Gadwa, J., Durini, G., Karakoc, I., Grier, A., & Neupert, B. (2023). Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis. Cancer Cell, 41(5), 950–969. Plewes, M. R., Talbott, H. A., Saviola, A. J., Woods, N. T., Schott, M. B., & Davis, J. S. (2023). Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis. Endocrinology, 164(9), bqad124. https://doi.org/10.1210/endocr/bqad124
Poole, L. G., Schmitt, L. R., Schulte, A., Groeneveld, D. J., Cline, H. M., Sang, Y., Hur, W. S., Wolberg, A. S., Flick, M. J., Hansen, K. C., & Luyendyk, J. P. (2023). Altered fibrinogen γ-chain cross-linking in mutant fibrinogen-γ(Δ5) mice drives acute liver injury. Journal of Thrombosis and Haemostasis : JTH, 21(8), 2175–2188. https://doi.org/10.1016/j.jtha.2023.04.003
Schaid, T. R. J., Cohen, M. J., D’Alessandro, A., Silliman, C. C., Moore, E. E., Sauaia, A., Dzieciatkowska, M., Hallas, W., Thielen, O., DeBot, M., Cralley, A., LaCroix, I., Erickson, C., Mitra, S., Banerjee, A., Jones, K., & Hansen, K. C. (2023). Trama Induces Intravascular Hemolysis, Exacerbated by Red Blood Cell Transfusion and Associated with Disrupted Arginine-Nitic Oxide. Shock (Augusta, Ga.), 59(1), 12–19. https://doi.org/10.1097/SHK.0000000000002036
Schaid, T. R. J., LaCroix, I., Cohen, M. J., Hansen, K. C., Moore, E. E., Sauaia, A., Cralley, A. L., Thielen, O., Hallas, W., Erickson, C., Mitra, S., Dzieciatkowska, M., Silliman, C. C., & D’Alessandro, A. (2023). Metabolomic and Proteomic Changes in Trauma-induced Hypocalcemia. Shock (Augusta, Ga.). https://doi.org/10.1097/SHK.0000000000002220
Schaid, T. R. J., LaCroix, I., Hansen, K. C., D’Alessandro, A., Moore, E. E., Sauaia, A., Dzieciatkowska, M., DeBot, M., Cralley, A. L., Thielen, O., Hallas, W., Erickson, C., Mitra, S., Banerjee, A., Jones, K., Silliman, C. C., & Cohen, M. J. (2023). A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. The Journal of Trauma and Acute Care Surgery, 94(3), 361–370. https://doi.org/10.1097/TA.0000000000003849
Smith, C. F., Brandehoff, N. P., Pepin, L., McCabe, M. C., Castoe, T. A., Mackessy, S. P., Nemkov, T., Hansen, K. C., & Saviola, A. J. (2023). Feasibility of detecting snake envenomation biomarkers from dried blood spots. Analytical Science Advances, 4(1–2), 26–36. https://doi.org/10.1002/ansa.202200050
Smith, C. F., Nikolakis, Z. L., Ivey, K., Perry, B. W., Schield, D. R., Balchan, N. R., Parker, J., Hansen, K. C., Saviola, A. J., Castoe, T. A., & Mackessy, S. P. (2023). Snakes on a plain: Biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake. BMC Biology, 21(1), 136. https://doi.org/10.1186/s12915-023-01626-x
Smith, C. F., Nikolakis, Z. L., Perry, B. W., Schield, D. R., Meik, J. M., Saviola, A. J., Castoe, T. A., Parker, J., & Mackessy, S. P. (2023). The best of both worlds? Rattlesnake hybrid zones generate complex combinations of divergent venom phenotypes that retain high toxicity. Biochimie, 213, 176–189. https://doi.org/10.1016/j.biochi.2023.07.008
Stearns-Reider, K. M., Hicks, M. R., Hammond, K. G., Reynolds, J. C., Maity, A., Kurmangaliyev, Y. Z., Chin, J., Stieg, A. Z., Geisse, N. A., Hohlbauch, S., Kaemmer, S., Schmitt, L. R., Pham, T. T., Yamauchi, K., Novitch, B. G., Wollman, R., Hansen, K. C., Pyle, A. D., & Crosbie, R. H. (2023). Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis. NPJ Regenerative Medicine, 8(1), 16. https://doi.org/10.1038/s41536-023-00287-2
Westfall, A. K., Gopalan, S. S., Perry, B. W., Adams, R. H., Saviola, A. J., Mackessy, S. P., & Castoe, T. A. (2023). Single-cell heterogeneity in snake venom expression is hardwired by co-option of regulators from progressively activated pathways. Genome Biology and Evolution, 15(6), evad109. https://doi.org/10.1093/gbe/evad109
Cralley, A. L., Moore, E. E., Fox, C. J., Kissau, D., DeBot, M., Schaid, T. R., Mitra, S., Hom, P., Fragoso, M., Ghasabyan, A., Erickson, C., D’Alessandro, A., Hansen, K. C., Cohen, M. J., Silliman, C. C., & Sauaia, A. (2022). Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury. Surgery, 172(2), 751–758. https://doi.org/10.1016/j.surg.2022.04.055
Crist, S. B., Nemkov, T., Dumpit, R. F., Dai, J., Tapscott, S. J., True, L. D., Swarbrick, A., Sullivan, L. B., Nelson, P. S., Hansen, K. C., & Ghajar, C. M. (2022a). Publisher Correction: Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nature Cell Biology, 24(7), 1177. https://doi.org/10.1038/s41556-022-00945-5
Crist, S. B., Nemkov, T., Dumpit, R. F., Dai, J., Tapscott, S. J., True, L. D., Swarbrick, A., Sullivan, L. B., Nelson, P. S., Hansen, K. C., & Ghajar, C. M. (2022b). Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nature Cell Biology, 24(4), 538–553. https://doi.org/10.1038/s41556-022-00881-4
Dai, J., Cimino, P. J., Gouin, K. H. 3rd, Grzelak, C. A., Barrett, A., Lim, A. R., Long, A., Weaver, S., Saldin, L. T., Uzamere, A., Schulte, V., Clegg, N., Pisarsky, L., Lyden, D., Bissell, M. J., Knott, S., Welm, A. L., Bielas, J. H., Hansen, K. C., … Ghajar, C. M. (2022). Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain. Nature Cancer, 3(1), 25–42. https://doi.org/10.1038/s43018-021-00297-3
Galbraith, M. D., Kinning, K. T., Sullivan, K. D., Araya, P., Smith, K. P., Granrath, R. E., Shaw, J. R., Baxter, R., Jordan, K. R., Russell, S., Dzieciatkowska, M., Reisz, J. A., Gamboni, F., Cendali, F., Ghosh, T., Guo, K., Wilson, C. C., Santiago, M. L., Monte, A. A., … Espinosa, J. M. (2022). Specialized interferon action in COVID-19. Proceedings of the National Academy of Sciences of the United States of America, 119(11). https://doi.org/10.1073/pnas.2116730119
Galvin, J., Curran, E., Arteaga, F., Goossens, A., Aubuchon-Endsley, N., McMurray, M. A., Moore, J., Hansen, K. C., Chial, H. J., Potter, H., Brodsky, J. L., & Coughlan, C. M. (2022). Proteasome activity modulates amyloid toxicity. FEMS Yeast Research, 22(1). https://doi.org/10.1093/femsyr/foac004
Gu, S., Mickael, C., Kumar, R., Lee, M. H., Sanders, L., Kassa, B., Harral, J., Williams, J., Hansen, K. C., Stenmark, K. R., Tuder, R. M., & Graham, B. B. (2022). The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension. Pulmonary Circulation, 12(3), e12105. https://doi.org/10.1002/pul2.12105
Guo, Q., Sun, D., Barrett, A. S., Jindal, S., Pennock, N. D., Conklin, M. W., Xia, Z., Mitchell, E., Samatham, R., Mirza, N., Jacques, S., Weinmann, S., Borges, V. F., Hansen, K. C., & Schedin, P. J. (2022). Mammary collagen is under reproductive control with implications for breast cancer. Matrix Biology: Journal of the International Society for Matrix Biology, 105, 104–126. https://doi.org/10.1016/j.matbio.2021.10.006
Hunter, J. D., Hancko, A., Shakya, P., Hill, R., Saviola, A. J., Hansen, K. C., Davis, M. E., & Christman, K. L. (2022). Characterization of decellularized left and right ventricular myocardial matrix hydrogels and their effects on cardiac progenitor cells. Journal of Molecular and Cellular Cardiology, 171, 45–55. https://doi.org/10.1016/j.yjmcc.2022.06.007
Jones, W. L., Ramos, C. R., Banerjee, A., Moore, E. E., Hansen, K. C., Coleman, J. R., Kelher, M., Neeves, K. B., Silliman, C. C., Di Paola, J., & Branchford, B. (2022). Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength. Platelets, 33(8), 1119–1131. https://doi.org/10.1080/09537104.2022.2078488
Klein, B. J., Feigerle, J. T., Zhang, J., Ebmeier, C. C., Fan, L., Singh, R. K., Wang, W. W., Schmitt, L. R., Lee, T., Hansen, K. C., Liu, W. R., Wang, Y.-X., Strahl, B. D., Anthony Weil, P., & Kutateladze, T. G. (2022). Taf2 mediates DNA binding of Taf14. Nature Communications, 13(1), 3177. https://doi.org/10.1038/s41467-022-30937-w
LaCroix, I. S., Cohen, M., Moore, E. E., Dzieciatkowska, M., Nemkov, T., Schaid, T. R. J., Debot, M., Jones, K., Silliman, C. C., Hansen, K. C., & D’Alessandro, A. (2022). Omics Markers of Red Blood Cell Transfusion in Trauma. International Journal of Molecular Sciences, 23(22). https://doi.org/10.3390/ijms232213815
Langouët-Astrié, C., Oshima, K., McMurtry, S. A., Yang, Y., Kwiecinski, J. M., LaRivière, W. B., Kavanaugh, J. S., Zakharevich, I., Hansen, K. C., Shi, D., Zhang, F., Boguslawski, K. M., Perelman, S. S., Su, G., Torres, V. J., Liu, J., Horswill, A. R., & Schmidt, E. P. (2022). The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia. Cell Reports, 41(9), 111721. https://doi.org/10.1016/j.celrep.2022.111721
Lee, E., Redzic, J. S., Nemkov, T., Saviola, A. J., Dzieciatkowska, M., Hansen, K. C., D’Alessandro, A., Dinarello, C., & Eisenmesser, E. Z. (2022). Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules (Basel, Switzerland), 27(14). https://doi.org/10.3390/molecules27144494
Morton, A. P., Hadley, J. B., Ghasabyan, A., Kelher, M. R., Moore, E. E., Bevers, S., Dzieciatkowska, M., Hansen, K. C., Cohen, M. S., Banerjee, A., & Silliman, C. C. (2022). The α-globin chain of hemoglobin potentiates tissue plasminogen activator induced hyperfibrinolysis in vitro. The Journal of Trauma and Acute Care Surgery, 92(1), 159–166. https://doi.org/10.1097/TA.0000000000003410
Murdock, M. H., Hussey, G. S., Chang, J. T., Hill, R. C., Nascari, D. G., Rao, A. V., Hansen, K. C., Foley, L. M., Hitchens, T. K., Amankulor, N. M., & Badylak, S. F. (2022). A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo. Oncotarget, 13, 426–438. https://doi.org/10.18632/oncotarget.28203
Nemkov, T., Kingsley, P. D., Dzieciatkowska, M., Malik, J., McGrath, K. E., Hansen, K. C., D’Alessandro, A., & Palis, J. (2022). Circulating primitive murine erythroblasts undergo complex proteomic and metabolomic changes during terminal maturation. Blood Advances, 6(10), 3072–3089. https://doi.org/10.1182/bloodadvances.2021005975
Nunns, G. R., Vigneshwar, N., Kelher, M. R., Stettler, G. R., Gera, L., Reisz, J. A., D’Alessandro, A., Ryon, J., Hansen, K. C., Gamboni, F., Moore, E. E., Peltz, E. D., Cohen, M. J., Jones, K. L., Sauaia, A., Liang, X., Banerjee, A., Ghasabyan, A., Chandler, J. G., … Silliman, C. C. (2022). Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS. Annals of Surgery, 276(6), e944–e954. https://doi.org/10.1097/SLA.0000000000004644
Paukovich, N., Henen, M. A., Hussain, A., Issaian, A., Sikela, J. M., Hansen, K. C., & Vögeli, B. (2022). Solution NMR backbone assignments of disordered Olduvai protein domain CON1 employing Hα-detected experiments. Biomolecular NMR Assignments, 16(1), 113–119. https://doi.org/10.1007/s12104-022-10068-5
Rizzo, A. N., Haeger, S. M., Oshima, K., Yang, Y., Wallbank, A. M., Jin, Y., Lettau, M., McCaig, L. A., Wickersham, N. E., McNeil, J. B., Zakharevich, I., McMurtry, S. A., Langouët-Astrié, C. J., Kopf, K. W., Voelker, D. R., Hansen, K. C., Shaver, C. M., Kerchberger, V. E., Peterson, R. A., … Schmidt, E. P. (2022). Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome. JCI Insight, 7(2). https://doi.org/10.1172/jci.insight.154573
Schaid, T. R. J., Hansen, K. C., Sauaia, A., Moore, E. E., DeBot, M., Cralley, A. L., Erickson, C., Silliman, C. C., Banerjee, A., Ghasabyan, A., Jones, K., Lacroix, I., Mitra, S., D’Alessandro, A., & Cohen, M. J. (2022). Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation. The Journal of Trauma and Acute Care Surgery, 93(5), 588–596. https://doi.org/10.1097/TA.0000000000003713
Ter Schiphorst, E., Hansen, K. C., Holm, M., & Hønge, B. L. (2022). Mother-to-child HIV-2 transmission: Comparison with HIV-1 and evaluation of factors influencing the rate of transmission. A systematic review. Transactions of the Royal Society of Tropical Medicine and Hygiene, 116(5), 399–408. https://doi.org/10.1093/trstmh/trab165
Wang, R. M., Mesfin, J. M., Hunter, J., Cattaneo, P., Guimarães-Camboa, N., Braden, R. L., Luo, C., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., Evans, S., & Christman, K. L. (2022). Myocardial matrix hydrogel acts as a reactive oxygen species scavenger and supports a proliferative microenvironment for cardiomyocytes. Acta Biomaterialia, 152, 47–59. https://doi.org/10.1016/j.actbio.2022.08.050
Calvete, J. J., Lomonte, B., Saviola, A. J., Bonilla, F., Sasa, M., Williams, D. J., Undheim, E. A., Sunagar, K., & Jackson, T. N. (2021). Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance. Toxicon: X, 9, 100070. https://doi.org/10.1016/j.toxcx.2021.100070
Catala, A., Dzieciatkowska, M., Wang, G., Gutierrez-Hartmann, A., Simberg, D., Hansen, K. C., D’Alessandro, A., & Catalano, C. E. (2021). Targeted Intracellular Delivery of Trastuzumab Using Designer Phage Lambda Nanoparticles Alters Cellular Programs in Human Breast Cancer Cells. ACS Nano, 15(7), 11789–11805. https://doi.org/10.1021/acsnano.1c02864
D’Alessandro, A., Hay, A., Dzieciatkowska, M., Brown, B. C., Morrison, E. J., Hansen, K. C., & Zimring, J. C. (2021). Protein-L-isoaspartate O-methyltransferase is required for in vivo control of oxidative damage in red blood cells. Haematologica, 106(10), 2726–2739. https://doi.org/10.3324/haematol.2020.266676
Diaz, M. D., Tran, E., Spang, M., Wang, R., Gaetani, R., Luo, C. G., Braden, R., Hill, R. C., Hansen, K. C., DeMaria, A. N., & Christman, K. L. (2021). Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model. JACC. Basic to Translational Science, 6(4), 350–361. https://doi.org/10.1016/j.jacbts.2021.01.003
Galbraith, M. D., Kinning, K. T., Sullivan, K. D., Baxter, R., Araya, P., Jordan, K. R., Russell, S., Smith, K. P., Granrath, R. E., Shaw, J. R., Dzieciatkowska, M., Ghosh, T., Monte, A. A., D’Alessandro, A., Hansen, K. C., Benett, T. D., Hsieh, E. W., & Espinosa, J. M. (2021). Seroconversion stages COVID19 into distinct pathophysiological states. eLife, 10. https://doi.org/10.7554/eLife.65508
Issaian, A., Hay, A., Dzieciatkowska, M., Roberti, D., Perrotta, S., Darula, Z., Redzic, J., Busch, M. P., Page, G. P., Rogers, S. C., Doctor, A., Hansen, K. C., Eisenmesser, E. Z., Zimring, J. C., & D’Alessandro, A. (2021). The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality. Haematologica, 106(11), 2971–2985. https://doi.org/10.3324/haematol.2020.278252
Kumar, S., Frid, M. G., Zhang, H., Li, M., Riddle, S., Brown, R. D., Yadav, S. C., Roy, M. K., Dzieciatkowska, M. E., D’Alessandro, A., Hansen, K. C., & Stenmark, K. R. (2021). Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages. JCI Insight, 6(21), e148382. https://doi.org/10.1172/jci.insight.148382
Maller, O., Drain, A. P., Barrett, A. S., Borgquist, S., Ruffell, B., Zakharevich, I., Pham, T. T., Gruosso, T., Kuasne, H., Lakins, J. N., Acerbi, I., Barnes, J. M., Nemkov, T., Chauhan, A., Gruenberg, J., Nasir, A., Bjarnadottir, O., Werb, Z., Kabos, P., … Weaver, V. M. (2021). Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nature Materials, 20(4), 548–559. https://doi.org/10.1038/s41563-020-00849-5
McCabe, M. C., Schmitt, L. R., Hill, R. C., Dzieciatkowska, M., Maslanka, M., Daamen, W. F., van Kuppevelt, T. H., Hof, D. J., & Hansen, K. C. (2021). Evaluation and Refinement of Sample Preparation Methods for Extracellular Matrix Proteome Coverage. Molecular & Cellular Proteomics : MCP, 20, 100079. https://doi.org/10.1016/j.mcpro.2021.100079
Mueller, A. C., Piper, M., Goodspeed, A., Bhuvane, S., Williams, J. S., Bhatia, S., Phan, A. V., Van Court, B., Zolman, K. L., Peña, B., Oweida, A. J., Zakem, S., Meguid, C., Knitz, M. W., Darragh, L., Bickett, T. E., Gadwa, J., Mestroni, L., Taylor, M. R. G., … Karam, S. D. (2021). Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer. Cancer Research, 81(12), 3255–3269. https://doi.org/10.1158/0008-5472.CAN-20-3892
Nemkov, T., Stefanoni, D., Bordbar, A., Issaian, A., Palsson, B. O., Dumont, L. J., Hay, A., Song, A., Xia, Y., Redzic, J. S., Eisenmesser, E. Z., Zimring, J. C., Kleinman, S., Hansen, K. C., Busch, M. P., & D’Alessandro, A. (2021). Blood donor exposome and impact of common drugs on red blood cell metabolism. JCI Insight, 6(3), 146175. https://doi.org/10.1172/jci.insight.146175
Percival, S. J., Russo, S., Priest, C., Hill, R. C., Ohlhausen, J. A., Small, L. J., Rempe, S. B., & Spoerke, E. D. (2021). Bio-inspired incorporation of phenylalanine enhances ionic selectivity in layer-by-layer deposited polyelectrolyte films. Soft Matter, 17(26), 6315–6325. https://doi.org/10.1039/d1sm00134e
Redzic, J. S., Lee, E., Born, A., Issaian, A., Henen, M. A., Nichols, P. J., Blue, A., Hansen, K. C., D’Alessandro, A., Vögeli, B., & Eisenmesser, E. Z. (2021). The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region. Journal of Molecular Biology, 433(15), 167108. https://doi.org/10.1016/j.jmb.2021.167108
Reed, B., Crawford, F., Hill, R. C., Jin, N., White, J., Krovi, S. H., Marrack, P., Hansen, K., & Kappler, J. W. (2021). Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine, 218(2). https://doi.org/10.1084/jem.20192135
Robinson, K. E., Holding, M. L., Whitford, M. D., Saviola, A. J., Yates III, J. R., & Clark, R. W. (2021). Phenotypic and functional variation in venom and venom resistance of two sympatric rattlesnakes and their prey. Journal of Evolutionary Biology, 34(9), 1447–1465. https://doi.org/10.1111/jeb.13907
Saldin, L. T., Klimak, M., Hill, R. C., Cramer, M. C., Huleihel, L., Li, X., Quidgley-Martin, M., Cardenas, D., Keane, T. J., Londono, R., Hussey, G., Kelly, L., Kosovec, J. E., Lloyd, E. J., Omstead, A. N., Zhang, L., Nieponice, A., Jobe, B., Hansen, K., … Badylak, S. F. (2021). The effect of normal, metaplastic, and neoplastic esophageal extracellular matrix upon macrophage activation. Journal of Immunology and Regenerative Medicine, 13, 100037. https://doi.org/10.1016/j.regen.2020.100037
Sullivan, K. D., Galbraith, M. D., Kinning, K. T., Bartsch, K. W., Levinsky, N. C., Araya, P., Smith, K. P., Granrath, R. E., Shaw, J. R., Baxter, R. M., Jordan, K. R., Russell, S. A., Dzieciatkowska, M. E., Reisz, J. A., Gamboni, F., Cendali, F. I., Ghosh, T., Monte, A. A., Bennett, T. D., … Espinosa, J. M. (2021). The COVIDome Explorer researcher portal. Cell Reports, 36(7), 109527. https://doi.org/10.1016/j.celrep.2021.109527
Syedain, Z. H., Haynie, B., Johnson, S. L., Lahti, M., Berry, J., Carney, J. P., Li, J., Hill, R. C., Hansen, K. C., Thrivikraman, G., Bianco, R., & Tranquillo, R. T. (2021). Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs. Science Translational Medicine, 13(585), eabb7225. https://doi.org/10.1126/scitranslmed.abb7225
Tzounakas, V. L., Anastasiadi, A. T., Dzieciatkowska, M., Karadimas, D. G., Stamoulis, K., Papassideri, I. S., Hansen, K. C., D’Alessandro, A., Kriebardis, A. G., & Antonelou, M. H. (2021). Proteome of Stored RBC Membrane and Vesicles from Heterozygous Beta Thalassemia Donors. International Journal of Molecular Sciences, 22(7). https://doi.org/10.3390/ijms22073369
Wang, Y., Hu, G., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., Zhang, X.-B., Yan, Z., & Pei, M. (2021). Matrix reverses immortalization-mediated stem cell fate determination. Biomaterials, 265, 120387. https://doi.org/10.1016/j.biomaterials.2020.120387
Agrawal, K., Hill, R. C., Wilkinson, B. L., Allison, P. B., & Thomas, C. E. (2020). Quantification of the anti-murine PD-1 monoclonal antibody RMP1-14 in BALB/c mouse plasma by liquid chromatography-tandem mass spectrometry and application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 412(3), 739–752. https://doi.org/10.1007/s00216-019-02292-1
Catala, A., Youssef, L. A., Reisz, J. A., Dzieciatkowska, M., Powers, N. E., Marchetti, C., Karafin, M., Zimring, J. C., Hudson, K. E., Hansen, K. C., Spitalnik, S. L., & D’Alessandro, A. (2020). Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis. Frontiers in Physiology, 11, 396. https://doi.org/10.3389/fphys.2020.00396
Combi, M., Shou, Y., Fougere, N., Tenishev, V., Altwegg, K., Rubin, M., Bockelée-Morvan, D., Capaccioni, F., Cheng, Y.-C., Fink, U., Gombosi, T., Hansen, K. C., Huang, Z., Marshall, D., & Toth, G. (2020). The Surface Distributions of the Production of the Major Volatile Species, H(2)O, CO(2), CO and O(2), from the Nucleus of Comet 67P/Churyumov-Gerasimenko throughout the Rosetta Mission as Measured by the ROSINA Double Focusing Mass Spectrometer. Icarus, 335, 113421. https://doi.org/10.1016/j.icarus.2019.113421
D’Alessandro, A., Thomas, T., Dzieciatkowska, M., Hill, R. C., Francis, R. O., Hudson, K. E., Zimring, J. C., Hod, E. A., Spitalnik, S. L., & Hansen, K. C. (2020). Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level. Journal of Proteome Research, 19(11), 4417–4427. https://doi.org/10.1021/acs.jproteome.0c00365
Frid, M. G., Thurman, J. M., Hansen, K. C., Maron, B. A., & Stenmark, K. R. (2020). Inflammation, immunity, and vascular remodeling in pulmonary hypertension; Evidence for complement involvement? Global Cardiology Science & Practice, 2020(1), e202001. https://doi.org/10.21542/gcsp.2020.1
Hernandez, M. J., Yakutis, G. E., Zelus, E. I., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., & Christman, K. L. (2020). Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels. Methods (San Diego, Calif.), 171, 20–27. https://doi.org/10.1016/j.ymeth.2019.09.015
Jordan, K. R., Hall, J. K., Schedin, T., Borakove, M., Xian, J. J., Dzieciatkowska, M., Lyons, T. R., Schedin, P., Hansen, K. C., & Borges, V. F. (2020). Extracellular vesicles from young women’s breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: A proteomic approach. Breast Cancer Research : BCR, 22(1), 128. https://doi.org/10.1186/s13058-020-01363-x
Li, J., Narayanan, K., Zhang, Y., Hill, R. C., He, F., Hansen, K. C., & Pei, M. (2020). Role of lineage-specific matrix in stem cell chondrogenesis. Biomaterials, 231, 119681. https://doi.org/10.1016/j.biomaterials.2019.119681
McCabe, M. C., Hill, R. C., Calderone, K., Cui, Y., Yan, Y., Quan, T., Fisher, G. J., & Hansen, K. C. (2020). Alterations in extracellular matrix composition during aging and photoaging of the skin. Matrix Biology Plus, 8, 100041. https://doi.org/10.1016/j.mbplus.2020.100041
Miszta, A., Kopec, A. K., Pant, A., Holle, L. A., Byrnes, J. R., Lawrence, D. A., Hansen, K. C., Flick, M. J., Luyendyk, J. P., de Laat, B., & Wolberg, A. S. (2020). A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice. Blood, 135(19), 1704–1717. https://doi.org/10.1182/blood.2019004267
Naranjo, J. D., Saldin, L. T., Sobieski, E., Quijano, L. M., Hill, R. C., Chan, P. G., Torres, C., Dziki, J. L., Cramer, M. C., Lee, Y. C., Das, R., Bajwa, A. K., Nossair, R., Klimak, M., Marchal, L., Patel, S., Velankar, S. S., Hansen, K. C., McGrath, K., & Badylak, S. F. (2020). Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus. Science Advances, 6(27), eaba4526. https://doi.org/10.1126/sciadv.aba4526
Northey, J. J., Barrett, A. S., Acerbi, I., Hayward, M.-K., Talamantes, S., Dean, I. S., Mouw, J. K., Ponik, S. M., Lakins, J. N., Huang, P.-J., Wu, J., Shi, Q., Samson, S., Keely, P. J., Mukhtar, R. A., Liphardt, J. T., Shepherd, J. A., Hwang, E. S., Chen, Y.-Y., … Weaver, V. M. (2020). Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. The Journal of Clinical Investigation, 130(11), 5721–5737. https://doi.org/10.1172/JCI129249
Pini, T., Parks, J., Russ, J., Dzieciatkowska, M., Hansen, K. C., Schoolcraft, W. B., & Katz-Jaffe, M. (2020). Obesity significantly alters the human sperm proteome, with potential implications for fertility. Journal of Assisted Reproduction and Genetics, 37(4), 777–787. https://doi.org/10.1007/s10815-020-01707-8
Tarullo, S. E., Hill, R. C., Hansen, K. C., Behbod, F., Borges, V. F., Nelson, A. C., & Lyons, T. R. (2020). Postpartum breast cancer progression is driven by semaphorin 7a-mediated invasion and survival. Oncogene, 39(13), 2772–2785. https://doi.org/10.1038/s41388-020-1192-9
Thomas, T., Stefanoni, D., Dzieciatkowska, M., Issaian, A., Nemkov, T., Hill, R. C., Francis, R. O., Hudson, K. E., Buehler, P. W., Zimring, J. C., Hod, E. A., Hansen, K. C., Spitalnik, S. L., & D’Alessandro, A. (2020). Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. Journal of Proteome Research, 19(11), 4455–4469. https://doi.org/10.1021/acs.jproteome.0c00606
Thomas, T., Stefanoni, D., Reisz, J. A., Nemkov, T., Bertolone, L., Francis, R. O., Hudson, K. E., Zimring, J. C., Hansen, K. C., Hod, E. A., Spitalnik, S. L., & D’Alessandro, A. (2020). COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight, 5(14), 140327. https://doi.org/10.1172/jci.insight.140327
Thrivikraman, G., Johnson, S. L., Syedain, Z. H., Hill, R. C., Hansen, K. C., Lee, H. S., & Tranquillo, R. T. (2020). Biologically-engineered mechanical model of a calcified artery. Acta Biomaterialia, 110, 164–174. https://doi.org/10.1016/j.actbio.2020.04.018
Wang, T., Hill, R. C., Dzieciatkowska, M., Zhu, L., Infante, A. M., Hu, G., Hansen, K. C., & Pei, M. (2020). Site-Dependent Lineage Preference of Adipose Stem Cells. Frontiers in Cell and Developmental Biology, 8, 237. https://doi.org/10.3389/fcell.2020.00237