Publications

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Cleland, N. R. W., Potter, G. J., Buck, C., Quang, D., Oldham, D., Neal, M., Saviola, A., Niemeyer, C. S., Dobrinskikh, E., & Bruce, K. D. (2024). Altered metabolism and DAM-signatures in female brains and microglia with aging. Brain Research, 1829, 148772. https://doi.org/10.1016/j.brainres.2024.148772

Cralley, A. L., Moore, E. E., LaCroix, I., Schaid, T. J., Thielen, O., Hallas, W., Hom, P., Mitra, S., Kelher, M., Hansen, K., Cohen, M., Silliman, C., Sauaia, A., & Fox, C. J. (2024). RESUSCITATIVE ENDOVASCULAR BALLOON OCCLUSION OF THE AORTA: ZONE 1 REPERFUSION-INDUCED COAGULOPATHY. Shock, 61(2), 322. https://doi.org/10.1097/SHK.0000000000002299

D’Alessandro, A., Earley, E. J., Nemkov, T., Stephenson, D., Dzieciatkowska, M., Hansen, K. C., Minetti, G., Champigneulle, B., Stauffer, E., Pichon, A., Furian, M., Verges, S., Kleinman, S., Norris, P. J., Busch, M. P., Page, G. P., & Kaestner, L. (2024). Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude. Proceedings of the National Academy of Sciences, 121(1), e2315930120. https://doi.org/10.1073/pnas.2315930120

Darragh, L. B., Nguyen, A., Pham, T. T., Idlett-Ali, S., Knitz, M. W., Gadwa, J., Bukkapatnam, S., Corbo, S., Olimpo, N. A., Nguyen, D., Court, B. V., Neupert, B., Yu, J., Ross, R. B., Corbisiero, M., Abdelazeem, K. N. M., Maroney, S. P., Galindo, D. C., Mukdad, L., … Karam, S. D. (2024). Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs. Med, 5(3), 254-270.e8. https://doi.org/10.1016/j.medj.2024.02.002

LaCroix, I. S., Moore, E. E., Cralley, A., Cendali, F. I., Dzieciatkowska, M., Hom, P., Mitra, S., Cohen, M., Silliman, C., Hansen, K. C., & D’Alessandro, A. (2024). Multiomics Signatures of Coagulopathy in a Polytrauma Swine Model Contrasted with Severe Multisystem Injured Patients. Journal of Proteome Research, acs.jproteome.3c00581. https://doi.org/10.1021/acs.jproteome.3c00581

Ross, R. B., Gadwa, J., Yu, J., Darragh, L. B., Knitz, M. W., Nguyen, D., Olimpo, N. A., Abdelazeem, K. N. M., Nguyen, A., Corbo, S., Van Court, B., Beynor, J., Neupert, B., Saviola, A. J., D’Alessandro, A., & Karam, S. D. (2024). PPARα Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in Counteraction. Clinical Cancer Research, OF1–OF18. https://doi.org/10.1158/1078-0432.CCR-23-3433

Bolf, E. L., Beadnell, T. C., Rose, M. M., D’Alessandro, A., Nemkov, T., Hansen, K. C., & Schweppe, R. E. (2023). Dasatinib and Trametinib Promote Anti-Tumor Metabolic Activity. Cells, 12(10). https://doi.org/10.3390/cells12101374

Bowers, S. L. K., Meng, Q., Kuwabara, Y., Huo, J., Minerath, R., York, A. J., Sargent, M. A., Prasad, V., Saviola, A. J., Galindo, D. C., Hansen, K. C., Vagnozzi, R. J., Yutzey, K. E., & Molkentin, J. D. (2023). Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics. Cells, 12(17), Article 17. https://doi.org/10.3390/cells12172174

Brown, R. D., Hunter, K. S., Li, M., Frid, M. G., Harral, J., Krafsur, G. M., Holt, T. N., Williams, J., Zhang, H., Riddle, S. R., Edwards, M. G., Kumar, S., Hu, C.-J., Graham, B. B., Walker, L. A., Garry, F. B., Buttrick, P. M., Lahm, T., Kheyfets, V. O., … Stenmark, K. R. (2023). Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model. American Journal of Physiology. Heart and Circulatory Physiology, 324(6), H804–H820. https://doi.org/10.1152/ajpheart.00614.2022

Bubak, A. N., Coughlan, C., Posey, J., Saviola, A. J., Niemeyer, C. S., Lewis, S. W. R., Lopez, S. B., Solano, A., Tyring, S. K., Delaney, C., Neeves, K. B., Mahalingam, R., Hansen, K. C., & Nagel, M. A. (2023). Zoster-Associated Prothrombotic Plasma Exosomes and Increased Stroke Risk. The Journal of Infectious Diseases, 227(8), 993–1001. https://doi.org/10.1093/infdis/jiac405

Cohen, M. J., Erickson, C. B., Lacroix, I. S., Debot, M., Dzieciatkowska, M., Schaid, T. R., Hallas, M. W., Thielen, O. N., Cralley, A. L., Banerjee, A., Moore, E. E., Silliman, C. C., D’Alessandro, A., & Hansen, K. C. (2023). Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients. In bioRxiv: The preprint server for biology (p. 2023.08.16.553446). https://doi.org/10.1101/2023.08.16.553446

Cralley, A. L., Erickson, C., Schaid, T. R. J., Hallas, W., Thielen, O., Mitra, S., Stafford, P., Hom, P., Silliman, C., Cohen, M. J., Moore, E. E., D’Alessandro, A., & Hansen, K. C. (2023). The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury. American Journal of Surgery, S0002-9610(23)00374-4. https://doi.org/10.1016/j.amjsurg.2023.07.040

De Man, R., McDonough, J. E., Adams, T. S., Manning, E. P., Myers, G., Vos, R., Ceulemans, L., Dupont, L., Vanaudenaerde, B. M., Wuyts, W. A., Rosas, I. O., Hagood, J. S., Ambalavanan, N., Niklason, L., Hansen, K. C., Yan, X., & Kaminski, N. (2023). A Multi-omic Analysis of the Human Lung Reveals Distinct Cell Specific Aging and Senescence Molecular Programs. In bioRxiv: The preprint server for biology (p. 2023.04.19.536722). https://doi.org/10.1101/2023.04.19.536722

Duran, P., Boscolo Sesillo, F., Cook, M., Burnett, L., Menefee, S. A., Do, E., French, S., Zazueta-Damian, G., Dzieciatkowska, M., Saviola, A. J., Shah, M. M., Sanvictores, C., Osborn, K. G., Hansen, K. C., Shtrahman, M., Christman, K. L., & Alperin, M. (2023). Proregenerative extracellular matrix hydrogel mitigates pathological alterations of pelvic skeletal muscles after birth injury. Science Translational Medicine, 15(707), eabj3138. https://doi.org/10.1126/scitranslmed.abj3138

Gadwa, J., Amann, M., Bickett, T. E., Knitz, M. W., Darragh, L. B., Piper, M., Van Court, B., Bukkapatnam, S., Pham, T. T., Wang, X.-J., Saviola, A. J., Deak, L. C., Umaña, P., Klein, C., D’Alessandro, A., & Karam, S. D. (2023). Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC. Cell Reports Medicine, 4(8), 101150. https://doi.org/10.1016/j.xcrm.2023.101150

Grabowsky, E. R., Saviola, A. J., Alvarado-Díaz, J., Mascareñas, A. Q., Hansen, K. C., Yates, J. R. 3rd, & Mackessy, S. P. (2023). Montane Rattlesnakes in México: Venoms of Crotalus tancitarensis and Related Species within the Crotalus intermedius Group. Toxins, 15(1). https://doi.org/10.3390/toxins15010072

Han, D. S., Erickson, C., Hansen, K. C., Kirkbride-Romeo, L., He, Z., Rodell, C. B., & Soranno, D. E. (2023). Mesenchymal Stem Cells Delivered Locally to Ischemia-Reperfused Kidneys via Injectable Hyaluronic Acid Hydrogels Decrease Extracellular Matrix Remodeling 1 Month after Injury in Male Mice. Cells, 12(13). https://doi.org/10.3390/cells12131771

LaCroix, I. S., Cralley, A., Moore, E. E., Cendali, F. I., Dzieciatkowska, M., Hom, P., Mitra, S., Cohen, M., Silliman, C., Sauaia, A., Hansen, K. C., & D’Alessandro, A. (2023). Omics Signatures of Tissue Injury and Hemorrhagic Shock in Swine. Annals of Surgery. https://doi.org/10.1097/SLA.0000000000005944

Lee, E., Redzic, J. S., Saviola, A. J., Li, X., Ebmeier, C. C., Kutateladze, T., Hansen, K. C., Zhao, R., Ahn, N., Sluchanko, N. N., & Eisenmesser, E. (2023). Molecular insight into the specific interactions of the SARS-Coronavirus-2 nucleocapsid with RNA and host protein. Protein Science : A Publication of the Protein Society, 32(4), e4603. https://doi.org/10.1002/pro.4603

McCabe, M. C., Gejji, V., Barnebey, A., Siuzdak, G., Hoang, L. T., Pham, T., Larson, K. Y., Saviola, A. J., Yannone, S. M., & Hansen, K. C. (2023). From volcanoes to the bench: Advantages of novel hyperthermoacidic archaeal proteases for proteomics workflows. Journal of Proteomics, 289, 104992. https://doi.org/10.1016/j.jprot.2023.104992

McCabe, M. C., Saviola, A. J., & Hansen, K. C. (2023). Mass Spectrometry-Based Atlas of Extracellular Matrix Proteins across 25 Mouse Organs. Journal of Proteome Research, 22(3), 790–801. https://doi.org/10.1021/acs.jproteome.2c00526

McCourt, J. L., Stearns-Reider, K. M., Mamsa, H., Kannan, P., Afsharinia, M. H., Shu, C., Gibbs, E. M., Shin, K. M., Kurmangaliyev, Y. Z., Schmitt, L. R., Hansen, K. C., & Crosbie, R. H. (2023). Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways. Skeletal Muscle, 13(1), 1. https://doi.org/10.1186/s13395-022-00311-x

Pei, M., Pei, Y. A., Zhou, S., Mikaeiliagah, E., Erickson, C., Giertych, B., Akhter, H., Wang, L., Stewart, A., Parenti, J., Wang, B., Wen, S., Sim, S., Quenneville, E., Hansen, K. C., Frisch, S., & Hu, G. (2023). Matrix from urine stem cells boosts tissue-specific stem cell mediated functional cartilage reconstruction. Bioactive Materials, 23, 353–367. https://doi.org/10.1016/j.bioactmat.2022.11.012

Piper, M., Hoen, M., Darragh, L. B., Knitz, M. W., Nguyen, D., Gadwa, J., Durini, G., Karakoc, I., Grier, A., & Neupert, B. (2023). Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis. Cancer Cell, 41(5), 950–969. Plewes, M. R., Talbott, H. A., Saviola, A. J., Woods, N. T., Schott, M. B., & Davis, J. S. (2023). Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis. Endocrinology, 164(9), bqad124. https://doi.org/10.1210/endocr/bqad124

Poole, L. G., Schmitt, L. R., Schulte, A., Groeneveld, D. J., Cline, H. M., Sang, Y., Hur, W. S., Wolberg, A. S., Flick, M. J., Hansen, K. C., & Luyendyk, J. P. (2023). Altered fibrinogen γ-chain cross-linking in mutant fibrinogen-γ(Δ5) mice drives acute liver injury. Journal of Thrombosis and Haemostasis : JTH, 21(8), 2175–2188. https://doi.org/10.1016/j.jtha.2023.04.003

Schaid, T. R. J., Cohen, M. J., D’Alessandro, A., Silliman, C. C., Moore, E. E., Sauaia, A., Dzieciatkowska, M., Hallas, W., Thielen, O., DeBot, M., Cralley, A., LaCroix, I., Erickson, C., Mitra, S., Banerjee, A., Jones, K., & Hansen, K. C. (2023). Trama Induces Intravascular Hemolysis, Exacerbated by Red Blood Cell Transfusion and Associated with Disrupted Arginine-Nitic Oxide. Shock (Augusta, Ga.), 59(1), 12–19. https://doi.org/10.1097/SHK.0000000000002036

Schaid, T. R. J., LaCroix, I., Cohen, M. J., Hansen, K. C., Moore, E. E., Sauaia, A., Cralley, A. L., Thielen, O., Hallas, W., Erickson, C., Mitra, S., Dzieciatkowska, M., Silliman, C. C., & D’Alessandro, A. (2023). Metabolomic and Proteomic Changes in Trauma-induced Hypocalcemia. Shock (Augusta, Ga.). https://doi.org/10.1097/SHK.0000000000002220

Schaid, T. R. J., LaCroix, I., Hansen, K. C., D’Alessandro, A., Moore, E. E., Sauaia, A., Dzieciatkowska, M., DeBot, M., Cralley, A. L., Thielen, O., Hallas, W., Erickson, C., Mitra, S., Banerjee, A., Jones, K., Silliman, C. C., & Cohen, M. J. (2023). A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. The Journal of Trauma and Acute Care Surgery, 94(3), 361–370. https://doi.org/10.1097/TA.0000000000003849

Smith, C. F., Brandehoff, N. P., Pepin, L., McCabe, M. C., Castoe, T. A., Mackessy, S. P., Nemkov, T., Hansen, K. C., & Saviola, A. J. (2023). Feasibility of detecting snake envenomation biomarkers from dried blood spots. Analytical Science Advances, 4(1–2), 26–36. https://doi.org/10.1002/ansa.202200050

Smith, C. F., Nikolakis, Z. L., Ivey, K., Perry, B. W., Schield, D. R., Balchan, N. R., Parker, J., Hansen, K. C., Saviola, A. J., Castoe, T. A., & Mackessy, S. P. (2023). Snakes on a plain: Biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake. BMC Biology, 21(1), 136. https://doi.org/10.1186/s12915-023-01626-x

Smith, C. F., Nikolakis, Z. L., Perry, B. W., Schield, D. R., Meik, J. M., Saviola, A. J., Castoe, T. A., Parker, J., & Mackessy, S. P. (2023). The best of both worlds? Rattlesnake hybrid zones generate complex combinations of divergent venom phenotypes that retain high toxicity. Biochimie, 213, 176–189. https://doi.org/10.1016/j.biochi.2023.07.008

Stearns-Reider, K. M., Hicks, M. R., Hammond, K. G., Reynolds, J. C., Maity, A., Kurmangaliyev, Y. Z., Chin, J., Stieg, A. Z., Geisse, N. A., Hohlbauch, S., Kaemmer, S., Schmitt, L. R., Pham, T. T., Yamauchi, K., Novitch, B. G., Wollman, R., Hansen, K. C., Pyle, A. D., & Crosbie, R. H. (2023). Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis. NPJ Regenerative Medicine, 8(1), 16. https://doi.org/10.1038/s41536-023-00287-2

Westfall, A. K., Gopalan, S. S., Perry, B. W., Adams, R. H., Saviola, A. J., Mackessy, S. P., & Castoe, T. A. (2023). Single-cell heterogeneity in snake venom expression is hardwired by co-option of regulators from progressively activated pathways. Genome Biology and Evolution, 15(6), evad109. https://doi.org/10.1093/gbe/evad109

Cralley, A. L., Moore, E. E., Fox, C. J., Kissau, D., DeBot, M., Schaid, T. R., Mitra, S., Hom, P., Fragoso, M., Ghasabyan, A., Erickson, C., D’Alessandro, A., Hansen, K. C., Cohen, M. J., Silliman, C. C., & Sauaia, A. (2022). Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury. Surgery, 172(2), 751–758. https://doi.org/10.1016/j.surg.2022.04.055

 

Crist, S. B., Nemkov, T., Dumpit, R. F., Dai, J., Tapscott, S. J., True, L. D., Swarbrick, A., Sullivan, L. B., Nelson, P. S., Hansen, K. C., & Ghajar, C. M. (2022a). Publisher Correction: Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nature Cell Biology, 24(7), 1177. https://doi.org/10.1038/s41556-022-00945-5

 

Crist, S. B., Nemkov, T., Dumpit, R. F., Dai, J., Tapscott, S. J., True, L. D., Swarbrick, A., Sullivan, L. B., Nelson, P. S., Hansen, K. C., & Ghajar, C. M. (2022b). Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nature Cell Biology, 24(4), 538–553. https://doi.org/10.1038/s41556-022-00881-4

 

Dai, J., Cimino, P. J., Gouin, K. H. 3rd, Grzelak, C. A., Barrett, A., Lim, A. R., Long, A., Weaver, S., Saldin, L. T., Uzamere, A., Schulte, V., Clegg, N., Pisarsky, L., Lyden, D., Bissell, M. J., Knott, S., Welm, A. L., Bielas, J. H., Hansen, K. C., … Ghajar, C. M. (2022). Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain. Nature Cancer, 3(1), 25–42. https://doi.org/10.1038/s43018-021-00297-3

 

Galbraith, M. D., Kinning, K. T., Sullivan, K. D., Araya, P., Smith, K. P., Granrath, R. E., Shaw, J. R., Baxter, R., Jordan, K. R., Russell, S., Dzieciatkowska, M., Reisz, J. A., Gamboni, F., Cendali, F., Ghosh, T., Guo, K., Wilson, C. C., Santiago, M. L., Monte, A. A., … Espinosa, J. M. (2022). Specialized interferon action in COVID-19. Proceedings of the National Academy of Sciences of the United States of America, 119(11). https://doi.org/10.1073/pnas.2116730119

 

Galvin, J., Curran, E., Arteaga, F., Goossens, A., Aubuchon-Endsley, N., McMurray, M. A., Moore, J., Hansen, K. C., Chial, H. J., Potter, H., Brodsky, J. L., & Coughlan, C. M. (2022). Proteasome activity modulates amyloid toxicity. FEMS Yeast Research, 22(1). https://doi.org/10.1093/femsyr/foac004

 

Gu, S., Mickael, C., Kumar, R., Lee, M. H., Sanders, L., Kassa, B., Harral, J., Williams, J., Hansen, K. C., Stenmark, K. R., Tuder, R. M., & Graham, B. B. (2022). The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension. Pulmonary Circulation, 12(3), e12105. https://doi.org/10.1002/pul2.12105

 

Guo, Q., Sun, D., Barrett, A. S., Jindal, S., Pennock, N. D., Conklin, M. W., Xia, Z., Mitchell, E., Samatham, R., Mirza, N., Jacques, S., Weinmann, S., Borges, V. F., Hansen, K. C., & Schedin, P. J. (2022). Mammary collagen is under reproductive control with implications for breast cancer. Matrix Biology: Journal of the International Society for Matrix Biology, 105, 104–126. https://doi.org/10.1016/j.matbio.2021.10.006

 

Hunter, J. D., Hancko, A., Shakya, P., Hill, R., Saviola, A. J., Hansen, K. C., Davis, M. E., & Christman, K. L. (2022). Characterization of decellularized left and right ventricular myocardial matrix hydrogels and their effects on cardiac progenitor cells. Journal of Molecular and Cellular Cardiology, 171, 45–55. https://doi.org/10.1016/j.yjmcc.2022.06.007

 

Jones, W. L., Ramos, C. R., Banerjee, A., Moore, E. E., Hansen, K. C., Coleman, J. R., Kelher, M., Neeves, K. B., Silliman, C. C., Di Paola, J., & Branchford, B. (2022). Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength. Platelets, 33(8), 1119–1131. https://doi.org/10.1080/09537104.2022.2078488

 

Klein, B. J., Feigerle, J. T., Zhang, J., Ebmeier, C. C., Fan, L., Singh, R. K., Wang, W. W., Schmitt, L. R., Lee, T., Hansen, K. C., Liu, W. R., Wang, Y.-X., Strahl, B. D., Anthony Weil, P., & Kutateladze, T. G. (2022). Taf2 mediates DNA binding of Taf14. Nature Communications, 13(1), 3177. https://doi.org/10.1038/s41467-022-30937-w

 

LaCroix, I. S., Cohen, M., Moore, E. E., Dzieciatkowska, M., Nemkov, T., Schaid, T. R. J., Debot, M., Jones, K., Silliman, C. C., Hansen, K. C., & D’Alessandro, A. (2022). Omics Markers of Red Blood Cell Transfusion in Trauma. International Journal of Molecular Sciences, 23(22). https://doi.org/10.3390/ijms232213815

 

Langouët-Astrié, C., Oshima, K., McMurtry, S. A., Yang, Y., Kwiecinski, J. M., LaRivière, W. B., Kavanaugh, J. S., Zakharevich, I., Hansen, K. C., Shi, D., Zhang, F., Boguslawski, K. M., Perelman, S. S., Su, G., Torres, V. J., Liu, J., Horswill, A. R., & Schmidt, E. P. (2022). The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia. Cell Reports, 41(9), 111721. https://doi.org/10.1016/j.celrep.2022.111721

 

Lee, E., Redzic, J. S., Nemkov, T., Saviola, A. J., Dzieciatkowska, M., Hansen, K. C., D’Alessandro, A., Dinarello, C., & Eisenmesser, E. Z. (2022). Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules (Basel, Switzerland), 27(14). https://doi.org/10.3390/molecules27144494

 

Morton, A. P., Hadley, J. B., Ghasabyan, A., Kelher, M. R., Moore, E. E., Bevers, S., Dzieciatkowska, M., Hansen, K. C., Cohen, M. S., Banerjee, A., & Silliman, C. C. (2022). The α-globin chain of hemoglobin potentiates tissue plasminogen activator induced hyperfibrinolysis in vitro. The Journal of Trauma and Acute Care Surgery, 92(1), 159–166. https://doi.org/10.1097/TA.0000000000003410

 

Murdock, M. H., Hussey, G. S., Chang, J. T., Hill, R. C., Nascari, D. G., Rao, A. V., Hansen, K. C., Foley, L. M., Hitchens, T. K., Amankulor, N. M., & Badylak, S. F. (2022). A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo. Oncotarget, 13, 426–438. https://doi.org/10.18632/oncotarget.28203

 

Nemkov, T., Kingsley, P. D., Dzieciatkowska, M., Malik, J., McGrath, K. E., Hansen, K. C., D’Alessandro, A., & Palis, J. (2022). Circulating primitive murine erythroblasts undergo complex proteomic and metabolomic changes during terminal maturation. Blood Advances, 6(10), 3072–3089. https://doi.org/10.1182/bloodadvances.2021005975

 

Nunns, G. R., Vigneshwar, N., Kelher, M. R., Stettler, G. R., Gera, L., Reisz, J. A., D’Alessandro, A., Ryon, J., Hansen, K. C., Gamboni, F., Moore, E. E., Peltz, E. D., Cohen, M. J., Jones, K. L., Sauaia, A., Liang, X., Banerjee, A., Ghasabyan, A., Chandler, J. G., … Silliman, C. C. (2022). Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS. Annals of Surgery, 276(6), e944–e954. https://doi.org/10.1097/SLA.0000000000004644

 

Paukovich, N., Henen, M. A., Hussain, A., Issaian, A., Sikela, J. M., Hansen, K. C., & Vögeli, B. (2022). Solution NMR backbone assignments of disordered Olduvai protein domain CON1 employing Hα-detected experiments. Biomolecular NMR Assignments, 16(1), 113–119. https://doi.org/10.1007/s12104-022-10068-5

 

Rizzo, A. N., Haeger, S. M., Oshima, K., Yang, Y., Wallbank, A. M., Jin, Y., Lettau, M., McCaig, L. A., Wickersham, N. E., McNeil, J. B., Zakharevich, I., McMurtry, S. A., Langouët-Astrié, C. J., Kopf, K. W., Voelker, D. R., Hansen, K. C., Shaver, C. M., Kerchberger, V. E., Peterson, R. A., … Schmidt, E. P. (2022). Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome. JCI Insight, 7(2). https://doi.org/10.1172/jci.insight.154573

 

Schaid, T. R. J., Hansen, K. C., Sauaia, A., Moore, E. E., DeBot, M., Cralley, A. L., Erickson, C., Silliman, C. C., Banerjee, A., Ghasabyan, A., Jones, K., Lacroix, I., Mitra, S., D’Alessandro, A., & Cohen, M. J. (2022). Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation. The Journal of Trauma and Acute Care Surgery, 93(5), 588–596. https://doi.org/10.1097/TA.0000000000003713

 

Ter Schiphorst, E., Hansen, K. C., Holm, M., & Hønge, B. L. (2022). Mother-to-child HIV-2 transmission: Comparison with HIV-1 and evaluation of factors influencing the rate of transmission. A systematic review. Transactions of the Royal Society of Tropical Medicine and Hygiene, 116(5), 399–408. https://doi.org/10.1093/trstmh/trab165

 

Wang, R. M., Mesfin, J. M., Hunter, J., Cattaneo, P., Guimarães-Camboa, N., Braden, R. L., Luo, C., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., Evans, S., & Christman, K. L. (2022). Myocardial matrix hydrogel acts as a reactive oxygen species scavenger and supports a proliferative microenvironment for cardiomyocytes. Acta Biomaterialia, 152, 47–59. https://doi.org/10.1016/j.actbio.2022.08.050

 

 

Calvete, J. J., Lomonte, B., Saviola, A. J., Bonilla, F., Sasa, M., Williams, D. J., Undheim, E. A., Sunagar, K., & Jackson, T. N. (2021). Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance. Toxicon: X, 9, 100070.  https://doi.org/10.1016/j.toxcx.2021.100070 

 

Catala, A., Dzieciatkowska, M., Wang, G., Gutierrez-Hartmann, A., Simberg, D., Hansen, K. C., D’Alessandro, A., & Catalano, C. E. (2021). Targeted Intracellular Delivery of Trastuzumab Using Designer Phage Lambda Nanoparticles Alters Cellular Programs in Human Breast Cancer Cells. ACS Nano, 15(7), 11789–11805. https://doi.org/10.1021/acsnano.1c02864

 

D’Alessandro, A., Hay, A., Dzieciatkowska, M., Brown, B. C., Morrison, E. J., Hansen, K. C., & Zimring, J. C. (2021). Protein-L-isoaspartate O-methyltransferase is required for in vivo control of oxidative damage in red blood cells. Haematologica, 106(10), 2726–2739. https://doi.org/10.3324/haematol.2020.266676

 

Diaz, M. D., Tran, E., Spang, M., Wang, R., Gaetani, R., Luo, C. G., Braden, R., Hill, R. C., Hansen, K. C., DeMaria, A. N., & Christman, K. L. (2021). Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model. JACC. Basic to Translational Science, 6(4), 350–361. https://doi.org/10.1016/j.jacbts.2021.01.003

 

Galbraith, M. D., Kinning, K. T., Sullivan, K. D., Baxter, R., Araya, P., Jordan, K. R., Russell, S., Smith, K. P., Granrath, R. E., Shaw, J. R., Dzieciatkowska, M., Ghosh, T., Monte, A. A., D’Alessandro, A., Hansen, K. C., Benett, T. D., Hsieh, E. W., & Espinosa, J. M. (2021). Seroconversion stages COVID19 into distinct pathophysiological states. eLife, 10. https://doi.org/10.7554/eLife.65508

 

Issaian, A., Hay, A., Dzieciatkowska, M., Roberti, D., Perrotta, S., Darula, Z., Redzic, J., Busch, M. P., Page, G. P., Rogers, S. C., Doctor, A., Hansen, K. C., Eisenmesser, E. Z., Zimring, J. C., & D’Alessandro, A. (2021). The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality. Haematologica, 106(11), 2971–2985. https://doi.org/10.3324/haematol.2020.278252

 

Kumar, S., Frid, M. G., Zhang, H., Li, M., Riddle, S., Brown, R. D., Yadav, S. C., Roy, M. K., Dzieciatkowska, M. E., D’Alessandro, A., Hansen, K. C., & Stenmark, K. R. (2021). Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages. JCI Insight, 6(21), e148382. https://doi.org/10.1172/jci.insight.148382

 

Maller, O., Drain, A. P., Barrett, A. S., Borgquist, S., Ruffell, B., Zakharevich, I., Pham, T. T., Gruosso, T., Kuasne, H., Lakins, J. N., Acerbi, I., Barnes, J. M., Nemkov, T., Chauhan, A., Gruenberg, J., Nasir, A., Bjarnadottir, O., Werb, Z., Kabos, P., … Weaver, V. M. (2021). Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nature Materials, 20(4), 548–559. https://doi.org/10.1038/s41563-020-00849-5

 

McCabe, M. C., Schmitt, L. R., Hill, R. C., Dzieciatkowska, M., Maslanka, M., Daamen, W. F., van Kuppevelt, T. H., Hof, D. J., & Hansen, K. C. (2021). Evaluation and Refinement of Sample Preparation Methods for Extracellular Matrix Proteome Coverage. Molecular & Cellular Proteomics : MCP, 20, 100079. https://doi.org/10.1016/j.mcpro.2021.100079

 

Mueller, A. C., Piper, M., Goodspeed, A., Bhuvane, S., Williams, J. S., Bhatia, S., Phan, A. V., Van Court, B., Zolman, K. L., Peña, B., Oweida, A. J., Zakem, S., Meguid, C., Knitz, M. W., Darragh, L., Bickett, T. E., Gadwa, J., Mestroni, L., Taylor, M. R. G., … Karam, S. D. (2021). Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer. Cancer Research, 81(12), 3255–3269. https://doi.org/10.1158/0008-5472.CAN-20-3892

 

Nemkov, T., Stefanoni, D., Bordbar, A., Issaian, A., Palsson, B. O., Dumont, L. J., Hay, A., Song, A., Xia, Y., Redzic, J. S., Eisenmesser, E. Z., Zimring, J. C., Kleinman, S., Hansen, K. C., Busch, M. P., & D’Alessandro, A. (2021). Blood donor exposome and impact of common drugs on red blood cell metabolism. JCI Insight, 6(3), 146175. https://doi.org/10.1172/jci.insight.146175

 

Percival, S. J., Russo, S., Priest, C., Hill, R. C., Ohlhausen, J. A., Small, L. J., Rempe, S. B., & Spoerke, E. D. (2021). Bio-inspired incorporation of phenylalanine enhances ionic selectivity in layer-by-layer deposited polyelectrolyte films. Soft Matter, 17(26), 6315–6325. https://doi.org/10.1039/d1sm00134e

 

Redzic, J. S., Lee, E., Born, A., Issaian, A., Henen, M. A., Nichols, P. J., Blue, A., Hansen, K. C., D’Alessandro, A., Vögeli, B., & Eisenmesser, E. Z. (2021). The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region. Journal of Molecular Biology, 433(15), 167108. https://doi.org/10.1016/j.jmb.2021.167108

 

Reed, B., Crawford, F., Hill, R. C., Jin, N., White, J., Krovi, S. H., Marrack, P., Hansen, K., & Kappler, J. W. (2021). Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. The Journal of Experimental Medicine, 218(2). https://doi.org/10.1084/jem.20192135

 

Robinson, K. E., Holding, M. L., Whitford, M. D., Saviola, A. J., Yates III, J. R., & Clark, R. W. (2021). Phenotypic and functional variation in venom and venom resistance of two sympatric rattlesnakes and their prey. Journal of Evolutionary Biology, 34(9), 1447–1465. https://doi.org/10.1111/jeb.13907 

 

Saldin, L. T., Klimak, M., Hill, R. C., Cramer, M. C., Huleihel, L., Li, X., Quidgley-Martin, M., Cardenas, D., Keane, T. J., Londono, R., Hussey, G., Kelly, L., Kosovec, J. E., Lloyd, E. J., Omstead, A. N., Zhang, L., Nieponice, A., Jobe, B., Hansen, K., … Badylak, S. F. (2021). The effect of normal, metaplastic, and neoplastic esophageal extracellular matrix upon macrophage activation. Journal of Immunology and Regenerative Medicine, 13, 100037. https://doi.org/10.1016/j.regen.2020.100037

 

Sullivan, K. D., Galbraith, M. D., Kinning, K. T., Bartsch, K. W., Levinsky, N. C., Araya, P., Smith, K. P., Granrath, R. E., Shaw, J. R., Baxter, R. M., Jordan, K. R., Russell, S. A., Dzieciatkowska, M. E., Reisz, J. A., Gamboni, F., Cendali, F. I., Ghosh, T., Monte, A. A., Bennett, T. D., … Espinosa, J. M. (2021). The COVIDome Explorer researcher portal. Cell Reports, 36(7), 109527. https://doi.org/10.1016/j.celrep.2021.109527

 

Syedain, Z. H., Haynie, B., Johnson, S. L., Lahti, M., Berry, J., Carney, J. P., Li, J., Hill, R. C., Hansen, K. C., Thrivikraman, G., Bianco, R., & Tranquillo, R. T. (2021). Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs. Science Translational Medicine, 13(585), eabb7225. https://doi.org/10.1126/scitranslmed.abb7225

 

Tzounakas, V. L., Anastasiadi, A. T., Dzieciatkowska, M., Karadimas, D. G., Stamoulis, K., Papassideri, I. S., Hansen, K. C., D’Alessandro, A., Kriebardis, A. G., & Antonelou, M. H. (2021). Proteome of Stored RBC Membrane and Vesicles from Heterozygous Beta Thalassemia Donors. International Journal of Molecular Sciences, 22(7). https://doi.org/10.3390/ijms22073369

 

Wang, Y., Hu, G., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., Zhang, X.-B., Yan, Z., & Pei, M. (2021). Matrix reverses immortalization-mediated stem cell fate determination. Biomaterials, 265, 120387. https://doi.org/10.1016/j.biomaterials.2020.120387

 

Agrawal, K., Hill, R. C., Wilkinson, B. L., Allison, P. B., & Thomas, C. E. (2020). Quantification of the anti-murine PD-1 monoclonal antibody RMP1-14 in BALB/c mouse plasma by liquid chromatography-tandem mass spectrometry and application to  a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 412(3), 739–752. https://doi.org/10.1007/s00216-019-02292-1

 

Catala, A., Youssef, L. A., Reisz, J. A., Dzieciatkowska, M., Powers, N. E., Marchetti, C., Karafin, M., Zimring, J. C., Hudson, K. E., Hansen, K. C., Spitalnik, S. L., & D’Alessandro, A. (2020). Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis. Frontiers in Physiology, 11, 396. https://doi.org/10.3389/fphys.2020.00396

 

Combi, M., Shou, Y., Fougere, N., Tenishev, V., Altwegg, K., Rubin, M., Bockelée-Morvan, D., Capaccioni, F., Cheng, Y.-C., Fink, U., Gombosi, T., Hansen, K. C., Huang, Z., Marshall, D., & Toth, G. (2020). The Surface Distributions of the Production of the Major Volatile Species, H(2)O, CO(2), CO and O(2), from the Nucleus of Comet 67P/Churyumov-Gerasimenko  throughout the Rosetta Mission as Measured by the ROSINA Double Focusing Mass  Spectrometer. Icarus, 335, 113421. https://doi.org/10.1016/j.icarus.2019.113421

 

D’Alessandro, A., Thomas, T., Dzieciatkowska, M., Hill, R. C., Francis, R. O., Hudson, K. E., Zimring, J. C., Hod, E. A., Spitalnik, S. L., & Hansen, K. C. (2020). Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level. Journal of Proteome Research, 19(11), 4417–4427. https://doi.org/10.1021/acs.jproteome.0c00365

 

Frid, M. G., Thurman, J. M., Hansen, K. C., Maron, B. A., & Stenmark, K. R. (2020). Inflammation, immunity, and vascular remodeling in pulmonary hypertension; Evidence for complement involvement? Global Cardiology Science & Practice, 2020(1), e202001. https://doi.org/10.21542/gcsp.2020.1

 

Hernandez, M. J., Yakutis, G. E., Zelus, E. I., Hill, R. C., Dzieciatkowska, M., Hansen, K. C., & Christman, K. L. (2020). Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels. Methods (San Diego, Calif.), 171, 20–27. https://doi.org/10.1016/j.ymeth.2019.09.015

 

Jordan, K. R., Hall, J. K., Schedin, T., Borakove, M., Xian, J. J., Dzieciatkowska, M., Lyons, T. R., Schedin, P., Hansen, K. C., & Borges, V. F. (2020). Extracellular vesicles from young women’s breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: A  proteomic approach. Breast Cancer Research : BCR, 22(1), 128. https://doi.org/10.1186/s13058-020-01363-x

 

Li, J., Narayanan, K., Zhang, Y., Hill, R. C., He, F., Hansen, K. C., & Pei, M. (2020). Role of lineage-specific matrix in stem cell chondrogenesis. Biomaterials, 231, 119681. https://doi.org/10.1016/j.biomaterials.2019.119681

 

McCabe, M. C., Hill, R. C., Calderone, K., Cui, Y., Yan, Y., Quan, T., Fisher, G. J., & Hansen, K. C. (2020). Alterations in extracellular matrix composition during aging and photoaging of the skin. Matrix Biology Plus, 8, 100041. https://doi.org/10.1016/j.mbplus.2020.100041

 

Miszta, A., Kopec, A. K., Pant, A., Holle, L. A., Byrnes, J. R., Lawrence, D. A., Hansen, K. C., Flick, M. J., Luyendyk, J. P., de Laat, B., & Wolberg, A. S. (2020). A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice. Blood, 135(19), 1704–1717. https://doi.org/10.1182/blood.2019004267

 

Naranjo, J. D., Saldin, L. T., Sobieski, E., Quijano, L. M., Hill, R. C., Chan, P. G., Torres, C., Dziki, J. L., Cramer, M. C., Lee, Y. C., Das, R., Bajwa, A. K., Nossair, R., Klimak, M., Marchal, L., Patel, S., Velankar, S. S., Hansen, K. C., McGrath, K., & Badylak, S. F. (2020). Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus. Science Advances, 6(27), eaba4526. https://doi.org/10.1126/sciadv.aba4526

 

Northey, J. J., Barrett, A. S., Acerbi, I., Hayward, M.-K., Talamantes, S., Dean, I. S., Mouw, J. K., Ponik, S. M., Lakins, J. N., Huang, P.-J., Wu, J., Shi, Q., Samson, S., Keely, P. J., Mukhtar, R. A., Liphardt, J. T., Shepherd, J. A., Hwang, E. S., Chen, Y.-Y., … Weaver, V. M. (2020). Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. The Journal of Clinical Investigation, 130(11), 5721–5737. https://doi.org/10.1172/JCI129249

 

Pini, T., Parks, J., Russ, J., Dzieciatkowska, M., Hansen, K. C., Schoolcraft, W. B., & Katz-Jaffe, M. (2020). Obesity significantly alters the human sperm proteome, with potential implications for fertility. Journal of Assisted Reproduction and Genetics, 37(4), 777–787. https://doi.org/10.1007/s10815-020-01707-8

 

Tarullo, S. E., Hill, R. C., Hansen, K. C., Behbod, F., Borges, V. F., Nelson, A. C., & Lyons, T. R. (2020). Postpartum breast cancer progression is driven by semaphorin 7a-mediated invasion and survival. Oncogene, 39(13), 2772–2785. https://doi.org/10.1038/s41388-020-1192-9

 

Thomas, T., Stefanoni, D., Dzieciatkowska, M., Issaian, A., Nemkov, T., Hill, R. C., Francis, R. O., Hudson, K. E., Buehler, P. W., Zimring, J. C., Hod, E. A., Hansen, K. C., Spitalnik, S. L., & D’Alessandro, A. (2020). Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. Journal of Proteome Research, 19(11), 4455–4469. https://doi.org/10.1021/acs.jproteome.0c00606

Thomas, T., Stefanoni, D., Reisz, J. A., Nemkov, T., Bertolone, L., Francis, R. O., Hudson, K. E., Zimring, J. C., Hansen, K. C., Hod, E. A., Spitalnik, S. L., & D’Alessandro, A. (2020). COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight, 5(14), 140327. https://doi.org/10.1172/jci.insight.140327

 

Thrivikraman, G., Johnson, S. L., Syedain, Z. H., Hill, R. C., Hansen, K. C., Lee, H. S., & Tranquillo, R. T. (2020). Biologically-engineered mechanical model of a calcified artery. Acta Biomaterialia, 110, 164–174. https://doi.org/10.1016/j.actbio.2020.04.018

 

Wang, T., Hill, R. C., Dzieciatkowska, M., Zhu, L., Infante, A. M., Hu, G., Hansen, K. C., & Pei, M. (2020). Site-Dependent Lineage Preference of Adipose Stem Cells. Frontiers in Cell and Developmental Biology, 8, 237. https://doi.org/10.3389/fcell.2020.00237