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The Structural Biology X-ray Crystallography Core facility is fully equipped for biomolecular crystallization, crystal screening, data collection, data processing, structure-determination and model building. The Rigaku/MSC Crystallization Robotics include: an Alchemist liquid handling robot for optimization screen production, a Phoenix drop setting robot, and an SPT Labtech mosquito Xtal-3 drop setting robot with humidifying chamber. The home source is composed of a Rigaku Micromax 007 high frequency microfocus X-ray generator, a VariMax high flux optic with adjustable divergence, an AFC11 4-axis goniometer, a Pilatus 200K 2D area detector, and an Oxford Cobra cryo-system. HKL-3000R is used for data collection and processing and is run on a Linux CentOS Dell Precision Workstation.
The facility is located in RC1 South Building Rm 1301. It is directed by Dr. Mair Churchill (Department of Pharmacology) and is managed by Dr. John Hardin (Department of Biochemistry and Molecular Genetics).
All publications resulting from the use of the X-Ray Crystallography Core Facility should acknowledge the Cancer Center Support Grant (P30CA046934) and submit the publication to PubMed Central.
Facility Manager, Research Associate
CU Anschutz Medical Campus - Department of Biochemistry and Molecular Genetics
12801 E. 17th Avenue, Mail Stop 8101
Aurora, CO 80045
Xray Crystallography Core Facility
University of Colorado School of Medicine
Research 1 South
12801 E. 17th Ave.
Aurora, CO 80045
Xray Generator Room
RC1-South, Rm 1301
RC1-South, Rm 1201