Scott Alper, PhD

Genetic control of TLR signaling pathways

David J. Barton, PhD

Picornavirus RNA translation and replication; hepatitis C virus and innate antiviral immunity

Leslie Berg, PhD
Professor, Chair

T cell activation, differentiation, and responses to infection and how these processes are regulated by T cell antigen receptor signaling

Aimee Bernard, PhD

The classroom is my laboratory; reimagining immunology education through creativity and innovation

John C. Cambier, PhD

BCR Antigen Receptor Structure and signaling, MHC Class II signaling, Inhibitory “Checkpoint” Receptor

Kelly Doran, PhD

Studying host - pathogen interactions in the central nervous system (CNS) and the female reproductive tract during infection and colonization

Breck Duerkop, PhD

Phage-bacteria interactions and mobile DNA related to antibiotic resistant bacteria and the microbiota

Rachel S. Friedman, PhD

Cell trafficking in type 1 diabetes; Immunotherapeutics development

Laurent Gapin, PhD

Mechanisms of iNKT cell development and antigen recognition

Andrew Getahun, PhD

Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development

James Hagman, PhD

Regulation of B cell development, epigenetics and cancer

Katie Haskins, PhD

Immunoregulation in autoimmune diabetes; pancreatic beta-cell autoantigens

Peter Henson, PhD

Innate immunity, inflammation and apoptotic cell recognition

Alexander Horswill, PhD

Bacterial pathogenesis including quorum-sensing signal production, biofilm development mechanisms, virulence factor function in host-pathogen

Elena Hsieh, MD

Mechanistic and translational questions in human immunology using high-dimensional single-cell mass cytomerty and ex-vivo cellular manipulation

Hua Huang, MD, PHD

We study signaling and transcriptional regulation of genes that control innate effector cell development and function, with a focus on how master transcription factors induce a network of downstream transcription factors and how these transcription factors and their associated enhancers and promoters detect signal inputs triggered by immunological stimuli and convert them into transcriptional outputs in the normal and diseased immune system

Jordan Jacobelli, PhD

Lymphocyte trafficking and cell-cell interactions in health and disease

John Kappler, PhD

Structure and function of the T-cell receptor and its ligands in autoimmunity, cancer and hypersensitivity

Ross Kedl, PhD

Intersection between innate and adaptive signals which lead to potent cellular immunity; exploration of how these signals might be manipulated for vaccine development and design

Marijke Keestra-Gounder, PhD

The major focus of my research program is to elucidate pathways of innate immunity that can distinguish harmless microbes from pathogens, thereby enabling the host to mount responses that are commensurate with the threat.

Laurel Lenz, PhD

Mechanisms for regulation of innate immune cell function and inflammation; impact of these in the context of microbial infections and in other disease contexts; and therapeutic implications

Philippa Marrack, PhD, FRS

T cell development; T-cell responses and death

Thomas E. Morrison, PhD

Immunological mechanisms that influence the clearance or persistence of arboviruses and protozoan parasites; molecular mechanisms by which pathogens counteract host innate and adaptive immune responses

Rebecca O'Brien, PhD

Specificity and function of gamma delta T lymphocytes

Roberta Pelanda, PhD

Molecular mechanisms of B cell development and selection and the development of autoimmunity

R. Lee Reinhardt, PhD

The role and regulation of CD4+ T cell subsets and their cytokines in settings of type-2 immunity, malignancy, and autoinflammatory disease

David Riches, PhD

Basic mechanisms involved in the development lung inflammation and fibrosis

Mercedes Rincon, PhD

Areas of research are Role of p38 MAPK and GSK3β in T cell development and function as well as IL-6 as a key regulator of T cell immune response in inflammatory diseases and cancer.

Rosemary Rochford, PhD

Co-infections with and immune responses to human gammaherpesviruses and P. falciparum malaria

Brian Russo, PhD

We are interested in uncovering the molecular mechanisms required for bacteria to cause infection and are focused on the intestinal pathogen Shigella flexneri

Michael Schurr, PhD

Transcriptional regulation and molecular biology of bacterial virulence factors

Jill Slansky, PhD

Immune response to cancer

Raul Torres, PhD

B cell development and antibody response, regulation of tumor immunity by lysophospholipids

Linda van Dyk, PhD
Professor, Vice Chair

Genetic and molecular approaches to infection and pathogenesis by lymphotropic herpesviruses

Andrés Vázquez-Torres, DVM, PhD

Molecular and redox determinants in the pathogenesis of intracellular bacteria

Martin Voskuil, PhD

Mycobacterium tuberculosis and Burkholderia pseudomallei mechanisms of latency and drug tolerance

Gongyi Zhang, PhD

Structural and functional studies of proteins, epigenetics