Genetic control of TLR signaling pathways
A focus on identifying the factors and pathways that enable autoreactive T cells to escape immune regulatory checkpoints and cause tissue damage, with the goal of using this knowledge for the development of innovative immunotherapies.
Innate immunity, inflammation and apoptotic cell recognition
Structure and function of the T-cell receptor and its ligands in autoimmunity, cancer and hypersensitivity
Our lab studies host-pathogen interactions with the goal of defining host and bacterial pathways involved in bacterial persistence.