Kristy Crooks PhD

Publications and Presentations

Selected Publications:

1. Haskell G, Adams M, Fan Z, Amin K, Badillo R, Zhou L, Bizon C, Chahin C, Greenwood R, Milko L, Shiloh-Malawsky Y, Crooks K, Strande N, Tennison M, Tilley C, Brandt A, Wilhelmsen K, Weck K, Evans J, Berg J. Diagnostic Utility of Exome Sequencing in the Evaluation of Neuromuscular Disorders. Neurology: Genetics. Forthcoming 2018.
2. Berg J, Foreman A, O’Daniel J, Booker J, Boshe L, Carey T, Crooks K, Jensen B, Juengst E, Lee K, Nelson D, Powell B, Powell C, Roche M, Skrzyniz C, Strande N, Weck K, Wilhelmsen W, Evans J. A semiquantitative metric for evaluating clinical actionability of incidental or secondary findings from genome-scale sequencing.  Genetics in Medicine (2016) 18, 467–475.
3. Crooks K, Edwardsen G, O’Connor S, Powell C, Vargo D, Vora N, Kaiser-Rogers K. Simultaneous false-positive and true-positive cell-free DNA test results in a trisomy 21 pregnancy with confined placental mosaicism for a cell line with trisomy for both chromosomes 18 and 21. Clinical Case Reports 2016; 4(1): 19–22.
4. Couser N, Masood M, Strande N, Foreman A, Crooks K, Weck K, Lu M, Wilhelmsen K, Roche M, Evans J, Berg J, Powell C. The phenotype of multiple congenital anomalies-hypotonia-seizures syndrome 1: Report and review. American Journal of Medical Genetics Part A. 2015;167(9):2176-81.
5. Lee K, Berg J, Milko L, Crooks K, Lu M, Bizon C, Owen P, Wilhelmsen K, Weck K, Evans J, Garg S. High diagnostic yield of whole exome sequencing in participants with retinal dystrophies in a clinical ophthalmology setting. American Journal of Ophthalmology. 2015;160(2):354-63.
6. Amendola M, Dorschner M, Robertson P, Salama J, Hart R, Shirts B, Murray M, Tokita M, Gallego C, Kim D, Bennett J, Crosslin D, Ranchalis J, Jones K, Rosenthal E, Jarvik E, Itsara A, Turner E, Herman D, Schleit J, Burt A, Jamal S,  Abrudan J, Johnson A, Conlin L, Dulik, Santani A, Metterville D, Kelly M, Foreman A, Lee K, Taylor K, Guo X, Crooks K, Kiedrowski L, Raffel L, Gordon O, Machini K, Desnick R, Biesecker L, Lubitz S, Mulchandani S, Cooper G, Joffe S, Richards S, Yang Y, Rotter J, Rich S, O'Donnell C, Berg J, Spinner N, Evans J, Fullerton S, Leppig K, Bennett R, Bird T, Sybert V, Grady W, Tabor H, Kim J, Bamshad M, Wilfond B, Motulsky A, Scott C, Pritchard C, Walsh T, Burke W, Raskind W, Byers P, Hisama F, Rehm H, Nickerson D, Jarvik G. Actionable exomic incidental findings in 6503 participants: challenges of variant classification. Genome Research. 2015; 25(3):305-15.
7. Fan, Z, Greenwood R, Felix A, Shiloh-Malawsky Y, Tennison M, Roche M, Crooks K, Weck K, Wilhelmsen K, Berg J, Evans J.   GCH1 heterozygous mutation identified by whole-exome sequencing as a treatable condition in a patient presenting with progressive spastic paraplegia. Journal of Neurology. 261.3 (2014): 622-624.
8. Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W, Budenz DL, Caprioli J, Crenshaw A, Crooks K, Delbono E, Doheny K, Friedman D, Gaasterland D, Gaasterland T, Laurie C, Lee R, Lichter P, Loomis S, Liu Y, Medeiros F, McCarty C, Mirel D, Moroi S, Musch D, Realini A, Rozsa F, Schuman J, Scott K, Singh K, Stein J, Trager E, Vanveldhuisen P, Vollrath D, Wollstein G, Yoneyama S, Zhang K, Weinreb R, Ernst J, Kellis M, Masuda T, Zack D, Richards J, Pericak-Vance M, Pasquale L, Haines J. (2012). Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. PLoS Genetics. 2012; 8(4): e1002654
9. Crooks K, Allingham R, Qin X, Liu Y, Gibson J, Santiago-Turla C, Larocque-Abramson K, Del Bono E, Challa P, Herndon LW, Akafo S, Wiggs J, Schmidt S, Hauser M.  Genome-wide linkage scan for primary open angle glaucoma: influences of ancestry and age at diagnosis. PLoS One. 2011; 6(7):e21967
10. Crooks K, Kleven D, Rodriguiz R, Wetsel W, McNamara J.  TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology. 2010; 58(7):1067-77.
11. Liu Y, Liu W, Crooks K, Schmidt S, Allingham R, Hauser M.  No evidence of association of heterozygous NTF4 mutations in Caucasian patients with primary open-angle glaucoma.  American Journal of Human Genetics. 2010; 86: 498-499.
12. Senderek J, Garvey S, Krieger M, Guergueltcheva V, Urtizberea A, Roos A, Elbracht M, Stendel C, Tournev I, Mihailova V, Feit H, Tramonte J, Hedera P, Crooks K, Bergmann C, Rudnik-Schöneborn S, Zerres K, Lochmüller H, Seboun E, Weis J, Beckmann J, Hauser M, Jackson C.  Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3.  American Journal of Human Genetics. 2009; 84(4):511-8.