This one-year fellowship is designed to give trainees a comprehensive molecular pathology experience. Fellows will rotate through the Colorado Molecular Correlates Laboratory (CMOCO) and the Precision Diagnostics Laboratory at Children's Hospital Colorado (CHCO). These labs see over 7000 clinical cases per year in solid tumor molecular oncology, molecular hematopathology, and inherited disease. Fellow time will focus on designing, interpreting, and reporting molecular diagnostics testing. Additional time spent at the Colorado Center for Personalized Medicine (CCPM) Biobank will expose the fellow to high-throughput large-scale genomic analysis (approximately 1000 specimens per week) utilized for pharmacogenomics, ACMG secondary findings, carrier screening, and genetic risk alleles (e.g., HFE, FVL). Fellows will also be exposed to mitochondrial and biochemical genetics testing and molecular microbiology at CHCO, cytogenetics at the Colorado Genetics Laboratory (CGL), and outpatient genetics clinics at the University of Colorado Hospital and CHCO. Additional elective opportunities are available depending on areas of fellow interest.
Fellow education is heavily based on one-on-one teaching during daily signout and rotations with the six MGP-boarded pathologists, 3 ACGME certified molecular geneticists, and additional clinical, technical, and scientific faculty and staff. The curriculum includes didactics and opportunities for practical laboratory experience, depending on the fellow’s level of training. The fellow will also audit the "Clinical Cytogenetics and Molecular Genetics" course for Genetic Counseling students and Laboratory Genetics and Genomics fellows. Additional activities include active fellow involvement in weekly lab management meetings, monthly molecular tumor boards, bimonthly journal clubs, and the BioBank incidental findings committee. Fellows are also expected to be involved in the validation of at least one clinical test during the year.
Applicants should be AP, CP, or AP/CP Board-eligible or Board-certified, other specialities (e.g., medical genetics and genomics) may also be considered; interview is required.