Current Test Menu

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Solid Tumor Testing (all below assays are performed on archival pathology tissue)

-56-gene panel mutational assay (next-generation sequencing (NGS))

-63-gene panel fusion assay (NGS)

-single gene mutational analysis

-allele-specific qPCR (EGFR, BRAF, KRAS, IDH1/2)

-Sanger sequencing of selected exons (EGFR, BRAF, KRAS, NRAS, CTNNB1, IDH1, IDH2, TERT promoter)

-promoter methylation testing (MGMT, MLH1)

-microsatellite instability (MSI) testing

-human papilloma virus (HPV) testing (qPCR)

-fluorescence in-situ hybridization (FISH)

-CMOCO can coordinate FISH offerings through the Colorado Genetics Laboratory (https://medschool.cuanschutz.edu/pathology/department-of-pathology-our-services/colorado-genetics-lab)

Other Testing

-bone marrow transplant chimerism testing (short tandem repeat (STR) analysis)

-maternal cell contamination testing (STR)

-sample contamination and identity testing (STR)

-Huntington disease genetic testing (HTT triplet repeat analysis)

**link to document currently on CMOCO website**

-thrombophilia genetic testing (single nucleotide polymorphism (SNP) analysis)

-hemochromatosis genetic testing (SNP analysis)