Molecular Pathology

Molecular Pathology (RRID: SCR_021995)

The Molecular Pathology Section offers clinical-grade sample processing and molecular testing for research cases.  All services are performed in a CLIA-certified environment and all molecular assays are accompanied by full data analysis (including bioinformatics analysis for NGS data)


  • Pathologist examination of tissue samples
  • Sample microdissection for internal testing 
  • Sample microdissection to release extract for external testing
  • 69-gene next-generation sequencing (NGS) mutation assay
  • 53 gene NGS gene fusion assay  
  • Single gene mutation/sequence analysis (Sanger, qPCR, sizing)
  • 24 locus STR analysis for identity confirmation and mixed sample analysis
  • Microsatellite instability testing 
  • MGMT & MLH1 promoter hyper-methylation testing
  • Custom assay design and evaluation
  • Testing for common polymorphisms in Factor 2, 5, HFE
  • Huntington Disease testing
  • Cystic fibrosis gene sequence by NGS
  • Digital droplet PCR (ddPCR) analysis of select targets

All services include

  • ​Experimental design consultation
  • A full analysis of all data (including bioinformatics analysis for NGS data)
  • An easy to interpret final report


  • Nanodrop and Qubit nucleic acid quantitation systems  
  • Agilent Bioanalyzer and TapeStation nucleic acid analysis systems  
  • Pipetting robot  
  • Thermocyclers  
  • Roche Lightcycler for quantitative PCR and RT-PCR analysis  
  • Qiagen Rotor-Gene Q instrument for qPCR  
  • Olympic microscopes, photomicroscopic equipment, and Leica microdissection scopes  
  • ABI 3500xl DNA analyzer  
  • Three Illumina MiSeq NGS sequencers  
  • Illumina NextSeq (for upcoming expanded NGS assays)
  • Biocartis Idylla
  • BioRad QX200 Droplet Digital PCR System


Fees are available upon request. Please contact Kurtis Davies, PhD for more information.

Contact Us

Dara Aisner, MD, PhD
Associate Director
Pathology Shared Resource
Molecular Pathology Section Leader

Kurtis Davies, PhD
Manager Molecular Pathology

p | 303-724-9257 

Main Email



BioScience 2, Suite 400 
12705 E. Montview Blvd.
Aurora CO, 80045​​​​



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