Rebecca Wolsky MD

Publications and Presentations

PEER-REVIEWED PUBLICATIONS

1. Mascarenhas JB, Littlejohn EL, Wolsky RJ, Young KP, Nelson M, Salgia R, Lang D. PAX3 and SOX10 activate MET receptor expression in melanoma. Pigment Cell Melanoma Res. 2010 Apr 23(2):225-37. PMID: 20067553  https://pubmed.ncbi.nlm.nih.gov/20067553/

2. Wend P, Runke S, Wend K, Anchondo B, Yesayan M, Jardon M, Hardie N, Loddenkemper C, Ulasov I, Lesniak MS, Wolsky R, Bentolila LA, Grant SG, Elashoff D, Lehr S, Latimer JJ, Bose S, Sattar H, Krum SA, Miranda-Carboni GA. WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer. EMBO Mol Med. 2013 Feb; 5(2):264-79. PMID: 23307470  https://pubmed.ncbi.nlm.nih.gov/23307470/

3. Wolsky RJ, Koo SC, Taxy JB, Tesic V. Photo quiz: not so humongous fungus or an imposter? Actinomyces meyeri sinusitis, Journal of Clinical Microbiology. J Clin Microbiol. 2015 Jun; 53(6):1789, 2004. PMID: 25976898  https://pubmed.ncbi.nlm.nih.gov/25976898/

4. Holloway RW, Abu-Rustum NR, Backes FJ, Boggess JF, Gotlieb WH, Jeffrey Lowery W, Rossi EC, Tanner EJ, Wolsky RJ. Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations. Gynecol Oncol. 2017 Aug;146(2):405-415. PMID: 28566221 https://pubmed.ncbi.nlm.nih.gov/28566221/

5. Wolsky RJ, Price M, Rabban JT. Mucosal proliferations in completely examined fallopian tubes accompanying ovarian low grade serous tumors: Neoplastic precursor lesions or normal variants of benign mucosa? Int J Gynecol Pathol. 2018 May; 37(3):262-274. PMID: 28700429 https://pubmed.ncbi.nlm.nih.gov/28700429/

6. Olivas AD, Taxy JB, Wolsky R, Antic T. Phyllodes tumor of the prostate with epithelial intestinal metaplasia. Am J Surg Pathol. Am J Surg Pathol. 2018 Jun;42(6):836-839. PMID: 29543676  https://pubmed.ncbi.nlm.nih.gov/29543676/

7. Wolsky RJ, Harbour LH, Mirza MK, Montag AG, Gwin K.  The stem cell associated transcription factor SOX2 as a diagnostic marker of high-grade squamous intraepithelial lesion of the uterine cervix in comparison to p16 and Ki-67. Appl Immunohistochem Mol Morphol. 2018 Jul;26(6);403-410. PMID: 27490766  https://pubmed.ncbi.nlm.nih.gov/27490766/

8. Cohen JN, Yeh I, Jordan RC, Wolsky RJ, Horvai AE, McCalmont TH, LeBoit PE. Cutaneous Non-Neural Granular Cell Tumors Harbor Recurrent ALK Gene Fusions. Am J Surg Pathol. 2018 Sep;42(9):1133-1142. PMID: 30001233  https://pubmed.ncbi.nlm.nih.gov/30001233/

9. Yi X, Ki Yun Le E, Mika D, Wolsky RJ, Van Slambrouck C, Leanse J, Nabhan C, and Yeo K. Re-engineering Critical Laboratory Testing for Timely Chemotherapeutic Management. J Appl Lab Med (JALM).  2018 Sep;3(1):240-249

10. Siegel MR, Wolsky RJ, Alvarez EA, Mengesha BM. Struma ovarii with atypical features and synchronous primary thyroid cancer: a case report and review of the literature. Arch Gynecol Obstet. 2019 Dec;300(6):1693-1707. PMID: 31679038 https://pubmed.ncbi.nlm.nih.gov/31679038/

 11. Carrillo NL, McKinney K, Wolsky RJ, Folz E. Adenoma Malignum. Accepted to Case in Point series, American College of Radiology website (cortex.acr.org), November 2019, expected publication October 13, 2021 https://cortex.acr.org/Cip/Pages/CaseView?Info=SgKZ%2fgWAeLYzkm6%2btPX9xxFML1FyOR1YgAPc5a%2bbXo70ts6jIK9vnQ%2bPCXiN4CAD

12. Greenland NY, Wolsky RJ, Darragh TM, Vohra P. Gastric-type endocervical adenocarcinoma and cervical cytology: Experience at a general hospital and review of the literature. Cytopathology. 2021 Jan;32(1):75-83. doi: 10.1111/cyt.12907. Epub 2020 Oct 5. PMID: 32851700  https://pubmed.ncbi.nlm.nih.gov/32851700/

13. Jordan KR, Sikora MJ, Slansky, JE, Minic A, Richer JK, Moroney MR, Hu J, Wolsky RJ, Watson ZL, Yamamoto TM, Costello JC, Clauset A, Behbakht K, Kumar R, Bitler B. The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval. Clinical Cancer Research. 2020 Dec 1;26(23):6362-6373. Epub 2020 Sep 14. PMID: 32928797 https://pubmed.ncbi.nlm.nih.gov/32928797/

14. Hill BL, Moroney MR, Post MD, Sawyer B, Sheeder J, Wolsky RJ, Lefkowits C. Can we safely forgo hysterectomy in non-fertility-sparing surgery for borderline ovarian tumors? Gynecol Oncol Rep. 2021 Feb 12;36:100730. doi: 10.1016/j.gore.2021.100730. PMID: 33665295; PMCID: PMC7900677  https://pubmed.ncbi.nlm.nih.gov/33665295/

15. Moroney M, Woodruff E, Qamar L, Bradford A, Wolsky R, Bitler B, Corr B. Inhibiting Wnt/beta-catenin in CTNNB1-mutated endometrial cancer. Mol Carcinog. 2021 Aug;60(8):511-523. doi: 10.1002/mc.23008. Epub 2021 May 26. PMID: 34038589. https://pubmed.ncbi.nlm.nih.gov/34038589/

16. Haag JG, Wolsky RJ, Moroney M, Sheren J, Sheeder J, Bitler B, Corr B. Clinicopathologic evaluation of CTNNB1 mutations in high-intermediate risk endometrial endometrioid adenocarcinoma. Haag JG, Wolsky RJ, Moroney MR, et al. Clinicopathologic Evaluation of CTNNB1 Mutations in High-Intermediate Risk Endometrial Endometrioid Carcinoma [published online ahead of print, 2022 Mar 14]. Int J Gynecol Pathol. 2022; PMID: 35283443. https://pubmed.ncbi.nlm.nih.gov/35283443/

17. Hill BL, Goon K, Fresia J, Sheeder J, Wolsky RJ, Alldredge J. Does lymph node dissection impact adjuvant treatment or survival outcomes in high-risk endometrial cancers?, Cureus. 2022;14(5):e24710. Published 2022 May 3. doi:10.7759/cureus.24710 PMID: 35663703 https://pubmed.ncbi.nlm.nih.gov/35663703/

18. Sanders BE, Wolsky R, Doughty ES, et al. Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A review and novel case with dual germline SMARCA4 and BRCA2 mutations. Gynecol Oncol Rep. 2022;44:101077. Published 2022 Oct 6. PMID: 36249907 https://pubmed.ncbi.nlm.nih.gov/36249907/

19. Shamir ER, Bean GR, Schwartz CJ, Vohra P, Wang A, Allard GM, Wolsky RJ, Garcia JJ, Chen YY, Krings G. Solid-basaloid adenoid cystic carcinoma of the breast: an aggressive subtype enriched for Notch pathway and chromatin-modifier mutations with MYB overexpression [published online ahead of print, 2023 Sep 1]. Mod Pathol. 2023;100324. doi:10.1016/j.modpat.2023.100324 https://pubmed.ncbi.nlm.nih.gov/37660928/

20. Davies KD, Smith LP, Guimaraes-Young A, Corr BR, Fisher, CM, Guntupalli SR, Berning AA, Post MD, Pino D, Aisner DL, Wolsky RJ. Prospective Clinical Prognostication of Endometrial Carcinomas Based on Next-Generation Sequencing and Immunohistochemistry-Real-World Implementation and Results at a Tertiary Care Center [published online ahead of print, 2023 Oct 4]. Int J Gynecol Pathol. 2023;10.1097/PGP.0000000000000994. doi:10.1097/PGP.0000000000000994. PMID: 37922951 https://pubmed.ncbi.nlm.nih.gov/37922951/

21. Van Kleunen, L. B., Ahmadian, M., Post, M. D., Wolsky, R. J., Rickert, C., Jordan, K. R., Hu, J., Richer, J. K., Brubaker, L. W., Marjon, N., Behbakht, K., Sikora, M. J., Bitler, B. G., & Clauset, A. (2024). The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma. Cancer immunology research, 10.1158/2326-6066.CIR-23-1109. Advance online publication. https://doi.org/10.1158/2326-6066.CIR-23-1109. PMID: 39115368 https://pubmed.ncbi.nlm.nih.gov/39115368/

SCHOLARLY REVIEWS

1. Wolsky RJ, Rabban JT. Benign sex cord-stromal tumors of the ovary that may mimic malignancies. Am J Surg Pathol Reviews and Reports, 2016; 21; 232-243

2. Smith LP, Brubaker LW, Wolsky RJ. It does exist! Diagnosis and management of thyroid carcinomas originating in struma ovarii. Surg Pathol Clin. 2023;16(1):75-86.

BOOK CHAPTERS

1. Wolsky RJ, Montag AG. Chapter 5: Female Genital Tract. Biopsy Interpretation: The Frozen Section, 2nd Ed. Taxy TB, Husain AN, Montag AG. Lippincott Williams & Wilkins, Philadelphia, 2014

2. Wolsky RJ, Taxy JB. Chapter 8: Breast and Sentinel Node. Biopsy Interpretation: The Frozen Section, 2nd Ed. Taxy TB, Husain AN, Montag AG. Lippincott Williams & Wilkins, Philadelphia, 2014

PEER-REVIEWED RESEARCH PRESENTATIONS & POSTERS

1. Wolsky RJ, Lengyel E, Montag A. Diagnostic markers in the differentiation of gynecologic and urologic clear cell carcinoma. United States & Canadian Academy of Pathology 99th Annual Meeting, March 2010, Washington, D.C., Poster

2. Wolsky RJ, Bills CB, Sattar H. Number of Positive Sentinel Nodes after Pre-Screening with Axillary Ultrasound is Predictive of Overall Axillary Tumor Burden in Breast Carcinoma. United States & Canadian Academy of Pathology 101st Annual Meeting, March 2012, Vancouver, Poster

3. Meyer BJ, Wolsky RJ, Abe H. Sonographic Features of Axillary Lymph Nodes with Metastatic Breast Cancer: Radiology-Pathology Correlation on the Spectrum of Disease. Radiological Society of North America, Annual Meeting, November 2012, Chicago, Poster

4. Wolsky RJ, Mirza MK, Montag A, Gwin K. The Stem Cell Associated Transcription Factor SOX2 as a Diagnostic Marker of Cervical Neoplasia in Comparison to p16 and Ki−67. United States & Canadian Academy of Pathology 102nd Annual Meeting, March 2013, Baltimore, Poster

5. Wolsky RJ, Mirza MK, Montag A, Gwin K. Expression of the Stem Cell Associated Transcription Factor SOX2 in Squamous Cell Carcinoma of the Vulva in Comparison to p16 and Ki−67. United States & Canadian Academy of Pathology 102nd Annual Meeting, March 2013, Baltimore, Poster

6. Ladanyi A, Nieman K, Penicka C, Mitra A, Kenny H, Gwin K, Wolsky RJ, Yamada SD, Lengyel E. Adipocytes Promote Overexpression of CD36 in Ovarian Cancer Cells Enhancing Tumorigenicity. Society of Gynecologic Oncology, 2013

7. Wolsky RJ, Vohra P, Garg K, Zaloudek C, Rabban J. Mucosal Proliferations in Completely Dissected Fallopian Tubes in a Blinded Study of Ovarian Serous Cystadenoma, Borderline Tumor and Low Grade Serous Carcinoma: Does a Precursor Tubal Lesion Exist? United States & Canadian Academy of Pathology 104th Annual Meeting, March 2015, Boston, Poster

8. Wolsky RJ, Price MA, Rabban J. Pre-Operative Distinction of High Grade Serous Carcinoma Versus Low Grade Serous Carcinoma in Women at Initial Presentation with Advanced Stage Pelvic Serous Cancer. United States & Canadian Academy of Pathology 106th Annual Meeting, March 2017, San Antonio, Poster

9. Ladwig N, Wolsky RJ, Sangoi A, Fadare O, Rabban JT. FOXL2 Immunoexpression in Endometrial Stromal Sarcoma and Non-Neoplastic Endometrial Stroma-Associated Lesions: A Potential Diagnostic Pitfall with Ovarian Sex Cord-Stromal Lesions. United States & Canadian Academy of Pathology 107th Annual Meeting, March 2018, Vancouver, Poster

10. Wolsky RJ, Devine WP, Grenert JP, Rabban JT, Chapman JS, Chen LM, Sangoi A, Garg K. Next generation sequencing of uterine PEComas as compared to uterine leiomyosarcomas. United States & Canadian Academy of Pathology 107th Annual Meeting, March 2018, Vancouver, Poster

11. Ladwig N, Wolsky RJ. SOX2 Distinguishes Squamous Cell Carcinoma of the Lower Gynecologic Tract From Endometrioid Adenocarcinoma With Squamous Differentiation. United States & Canadian Academy of Pathology 107th Annual Meeting, March 2018, Vancouver, Poster

12. Devine WP, Garg K, Rabban JT, Zaloudek C, Grenert JP, Sangoi A, Wolsky RJ. Integrated Assessment of ATRX Mutation Status and Protein Expression by IHC in Uterine Mesenchymal Tumors. United States & Canadian Academy of Pathology 108th Annual Meeting, March 2019, National Harbor, MD. Poster

13. Jankowski T, Umetsu S, Joseph N, Wolsky RJ, Ladwig N. The Combination of Aberrant p53 and Rb IHC is Highly Specific for Leiomyosarcoma. United States & Canadian Academy of Pathology 109th Annual Meeting, February 2020, Los Angeles, CA. Poster

14. Hill BL, Moroney M, Sheeder J, Sawyer B, Post M, Wolsky RJ, Lefkowits C, Guiahi M. Can we safely forgo hysterectomy in non-fertility sparing surgery for borderline ovarian tumors? Western Association of Gynecologic Oncologists, June 2020 Virtual Annual Meeting. Poster

15. Ho L, Arnold MA, Clay M, Collins G, Hong E, Potterveld S, Wolsky RJ, Berning A, Arnold CA.Onboarding a Resident-Level Gross Photo Competition to Improve the Quality of the Gross Exam and Engagement. United States and Canadian Academy of Pathology Virtual Annual Meeting. March 2021. Poster

• ·         Also presented at The University of Colorado Anschutz Campus. 2nd Virtual Poster Session, Dept. of Pathology, Aurora, Colorado. 2021. Poster

  16. Reiter D, Wolsky RJ. Cervical Biopsies Diagnosed as “At Least High Grade Squamous Intraepithelial Lesion (HSIL)” or “At Least Adenocarcinoma in Situ (AIS)” and Morphologic Predictors of Invasive Carcinoma. United States and Canadian Academy of Pathology Virtual Annual Meeting. March 2021.  Poster

• ·         Also presented at The University of Colorado Anschutz Campus. 2nd Virtual Poster Session, Dept. of Pathology, Aurora, Colorado. 2021. Poster

  17. Hill BL, Goon K, Fresia J, Sheeder J, Wolsky RJ, Alldredge J. Does lymph node dissection impact adjuvant treatment or survival outcomes in high-risk endometrial cancers? Western Association of Gynecologic Oncologists, June 2021 Virtual Annual Meeting. Poster

  18. Gasper C, Wolsky RJ, Ladwig N, Rabban JT. Ovarian steroid cell tumors lack peri-cellular reticulin staining: A potential pitfall with luteinized adult granulosa cell tumor that is resolved by FOXL2 immunostaining. United States & Canadian Academy of Pathology 110th Annual Meeting, March 2022, Los Angeles, CA. Poster

  19. Pino D, Smith L, Davies K, Berning A, Post M, Corr B, Guntupalli S, Fisher C, Aisner D, Wolsky RJ. Implementation of endometrial cancer TCGA classification using ProMisE: Experience at a tertiary care center. United States & Canadian Academy of Pathology 110th Annual Meeting, March 2022, Los Angeles, CA. Poster

• ·         Also presented at The University of Colorado Anschutz Campus, Dept. of Pathology, Poster Session. Aurora, Colorado. 2022. Poster

  20. Guimaraes-Young A, Smith L, Aisner D, Wolsky RJ, Corr B, Davies K. Targeted next-generation sequencing panel reveals differences in mutational patterns between endometrial cancer molecular classifier subgroups. Association for Molecular Pathology 2022 Annual Meeting, Pheonix, AZ. Poster

  21. Wolsky RJ, Fadare O, Rabban JT, Detection of incidental serous tubal intraepithelial carcinoma (STIC) in women without known risk for hereditary ovarian cancer undergoing surgery unrelated to tubo-ovarian cancer: Tissue sampling triage strategies based on patient age for resource-limited practices. United States & Canadian Academy of Pathology 111th Annual Meeting, March 2023, New Orleans, LA. Poster

  22. Bradley R Corr, Junxiao Hu, Christine Walsh, Jill Alldredge, Lindsay Brubaker, Saketh Guntupalli, Kian Behbakht, Carolyn Lefkowits, Christine M Fisher, Daniel Spinosa, Hector Porragas-Paseiro, Devon Pino, Lynelle P Smith, Amy Guimaraes-Young, Kurtis Davies, Dara L. Aisner, Rebecca J Wolsky. Uniform prospective molecular analysis of endometrial carcinoma: feasibility, outcomes, and effect on management. European Society of Medical Oncology, October 2023, Madrid, Spain. Poster

   23. Smith LP, Knoeckel C, Black M, Sheren J, Corr BR, Wolsky RJ. Morphologic compartmentalization of CTNNB1 mutation to glands and/or squamous morules in endometrial endometrioid adenocarcinoma: Practical implications for using Beta-catenin IHC to guide localization of DNA sampling for mutational analysis. Accepted for United States & Canadian Academy of Pathology 112th Annual Meeting, March 2024, Baltimore, MD. Poster in Stowell-Orbison awards eligible session.

   24. Smith LP, Davies KD, Guimaraes-Young A, Wolsky RJ. Retrospective reclassification of 188 consecutive endometrial carcinomas by FIGO 2023 staging, including molecular classification. Accepted for United States & Canadian Academy of Pathology 112th Annual Meeting, March 2024, Baltimore, MD. Platform Presentation and Poster.

   25. Hagemann I, Parra-Herran C, et al, Wolsky RJ, Staats PN, Rabban JT. Experience of U.S. gynecologic pathology fellowships with a unified application approach and timeline. Accepted for United States & Canadian Academy of Pathology 112th Annual Meeting, March 2024, Baltimore, MD. Poster.

   26. Xiong J, Smith LP, Black M, Wolsky RJ, Post MD. Histopathologic correlation with ARID1A immunohistochemistry in endometrial carcinomas, including description of subclonal ARID1A loss. Accepted for United States & Canadian Academy of Pathology 112th Annual Meeting, March 2024, Baltimore, MD. Poster in Stowell-Orbison awards eligible session.