Payne Lab for Orthopedic Regenerative Medicine

Payne Lab

Lab Mission

The Payne Lab focuses on the development of functional regenerative medicine approaches for bone and cartilage tissues, with a particular interest in treating growth plate cartilage injuries affecting the pediatric population.

Collaborations and Tools

The lab uses cell- and biomaterial-based approaches to develop novel treatments for growth plate cartilage regeneration. These are tested in various animal models of orthopedic injury. The lab collaborates with faculty at both the CU Anschutz Medical Campus and the CU Boulder campus, as well as the Colorado School of Mines.

Work We Do

We study growth plate cartilage injuries at a mechanistic level where we investigate the role of angiogenesis in bony repair tissue formation, which occurs after growth plate injury and is the central cause of associated growth abnormalities. At a translational level, we are evaluating different potential treatments by combining stem cells, biomaterials, and 3D printing. Other active projects in the laboratory are related to enhancing bone formation during spinal fusion, as well as developing regenerative medicine approaches for post-traumatic osteoarthritis.

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