This site is specific for researchers interested in utilizing the D3SR Arm, which specializes in HTS/HCS probe and drug discovery using cellular and biochemical systems. We also specialize in three-dimensional (3D) HTS/HCS of complex cell-based models, organoids and tumor organoids (cell line or patient derived). This facility is newly renovated and features a new state-of-the-art custom robotic automation platform (the Explorer G3) that integrates new HTS/HCS instrumentation and equipment from PerkinElmer, Tek-Matic, and other leading vendors.
The Explorer G3 Work Station (PerkinElmer) is a custom designed automation platform that is fully enclosed, maintaining a clean sterile environment through a HEPA filtration system. The Explorer G3 has three levels, the main deck, and a middle and lower deck used to house instrumentation and equipment. The Explorer G3 has a track system robotic arm that integrates equipment on both the main and middle decks.
Other Equipment Utilized for Assay Development Not Integrated with The Explorer G3
Kinase Inhibitor Library (SelleckChem): 875 compounds including clinically relevant or FDA approved kinase inhibitors.
Spectrum Collection (Discovery Systems): 2,320 compounds approved drugs (50%), diverse natural products (30%), and other bioactive compounds (20%).
Custom Drug-Like Diversity Sets (120,000 compounds): These libraries are intended for discovering drug-like molecules that can be translated into novel intellectual property. Inherent to these libraries are derivatives of each chemical scaffold, which can yield SAR (structure-activity relationship) that can guide downstream medicinal chemistry efforts. These libraries have been filtered to remove undesirable compounds (PAINS)
For more information on equipment, instrumentation and pricing, or to obtain consultation or project cost estimates please click here to visit the D3SR Arm 1 iLabs Website.
Hours of Operation
Monday-Friday, 9 am -5 pm
p | (303)724-4116
12850 E Montview Blvd, V20-2211
Skaggs School of Pharmacy and Pharmaceutical Sciences
University of Colorado Anschutz Medical Campus
Aurora, CO 80045