Citalopram/Escitalopram Tip Sheet

The following information is intended for use by providers who are attempting to prescribe citalopram or escitalopram to patients with certain CYP2C19 genetic variants.  

For immediate questions, send a secure chat message to Groups: Pharmacogenomics Service in UCHealth's EHR.

References:

1. Hicks JK, et al; Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors. Clin Pharmacol Ther. 2015 Aug;98(2):127-34.

2. https://cpicpgx.org/guidelines/guideline-for-selective-serotonin-reuptake-inhibitors-and-cyp2d6-and-cyp2c19/

3. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-revised-recommendations-celexa-citalopram-hydrobromide-related