Learn About Available CCPM Biobank Research Study Resources

The Colorado Biobank Portal (CBP) is an application developed by CCPM that displays genome-wide genetic association studies for many phenotypes. The CBP is updated to the latest data freeze of CCPM biobank research study participants.

To request a access to the CBP, please submit an access request here. 

Request a cohort count (aggregate counts of CCPM biobank research study participants within your defined cohort). Your cohort can be defined with clinical and genetic characteristics. For example, if you want to know how many CCPM biobank research study participants have a certain ICD code and genotype, we can generate a cohort count for you.

To request a cohort count, please submit an Access to Biobank (ABC) proposal request here. 

QC'd resources

• Specific SNPs or region of interest*
• Allele frequency data*
• SNP imputation quality scores*
• Genome-wide principal components analysis (PCA) data*
• Inferred genetic similarity group assignments*
• QC'd and imputed data*-good for Genome-Wide Association Studies (GWAS) and Polygenic Risk Scores (PRS)
  • ~99,500 samples across ~49M variants
• QC'd whole exome sequencing data (WES)*-good for rare variant analysis (gene-based tests)
  • ~95,500 samples across ~8.6M variants; requires agreement with Regeneron Genetics Center (RGC)

Please note that CCPM makes every effort to screen for bone marrow transplants. However, data may contain samples whose genotype calls match the donor and not the patient. QC'd resources make every effort to exclude these samples.

Raw genetic data*

• Raw genetic data may be requested. This data may include patients with bone marrow transplants whose genotype calls match the donor and not the patient, as well as samples and variants that do not pass CCPM QC thresholds. Users agree to use resources at their own risk!

To request access to these data products, please submit an Access to Biobank Committee (ABC) proposal request here. 

*Some data has restrictions for use, please see the data use disclaimer at the bottom of this webpage.

As the enterprise health data warehouse, Health Data Compass (HDC) integrates patient data from the electronic medical records at UCHealth and Children's Hospital Colorado, provider billing data from CU Medicine and genomics data from the Colorado Center for Personalized Medicine. These data are further enriched with various state and public data sources, including death registry, ACS Census environmental and social determinants of health data. Compass makes these data available to our partners through a range of methods, from self-service de-identified cohort analyses to fully identified, line-level datasets suitable for advanced analytics.

To request access to CCPM biobank resources (e.g., data, biospecimens) paired with electronic medical record data, please submit an Access to Biobank Committee (ABC) proposal request here. 

CCPM partners with the Center for Innovative Design and Analysis (CIDA) to support campus analytical needs for research using CCPM biobank data. CIDA, known for sustainable and scalable research analytics, helps make biobank genetic data accessible to researchers who need support in completing analyses, such as a Genome-Wide Association Study or calculate Polygenic Risk Scores.*

• Current research freeze (~99,500 samples across ~49 million variants, does not require agreement with Regeneron Genetics Center [RGC]).
• Past research freezes of CCPM biobank data may be made available upon request (may require agreement with RGC).
• Whole exome sequencing data-(~95,500 samples across 8.6 million variants; requires agreement with RGC).

To submit an Access to Biobank Committee (ABC) proposal request including support for genetic analyses, click here. 

*Some data has restrictions for use; please see the data use disclaimer at the bottom of this webpage.