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Biobank

Colorado Center for Personalized Medicine

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Pharmacogenetic Results

Results that may predict response to medications. Information for healthcare professionals.

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Overview of Pharmacogenetic Return of Results

Pharmacogenetics (PGx) is the use of genetic information to help guide drug selection and dosing.  

The Colorado Center for Personalized Medicine is enrolling participants in a research Biobank, primarily focused on genetics. 

Biobank participants may give permission to return available genetic test results, including select, clinically-actionable PGx test results to their UCHealth electronic health record (EHR). 

Genes in Focus

The Biobank is returning results for 7 pharmacogenetic (PGx) genes: CYP2C19, SLCO1B1, DPYD, CYP2C9, TPMT, NUDT15, and ABCG2.

Prerequisites for Return

In order for results to be available to providers, a Biobank participant must have a blood or saliva sample collected and processed and sign appropriate consent for return.  

Scroll down to see FAQs

PGx Exceptions

Click here to learn how liver transplant & allogeneic BMT impact PGx results. 
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Drug-Gene Pairs

Antipsychotics & CYP2D6
Brivaracetam & CYP2C19
Clobazam & CYP2C19

 

Clopidogrel & CYP2C19
Codeine-Tramadol & CYP2D6
Fluoropyrimidines & DPYD
Irinotecan & UGT1A1
Metoclopramide & CYP2D6
Metoprolol & CYP2D6
NSAIDs & CYP2C9
Ondansetron & CYP2D6
Phenytoin-Fosphenytoin & CYP2C9
PPIs & CYP2C19
Rosuvastatin & ABCG2/SLCO1B1
Siponimod & CYP2C9
SSRIs & CYP2C19/CYP2D6
Statins & SLCO1B1
TCAs & CYP2D6
Thiopurines & TPMT/NUDT15
Voriconazole & CYP2C19

Pharmacogenetic Tip Sheets

Brivaracetam Tip Sheet
Clobazam Tip Sheet
Codeine-Tramadol Tip Sheet
DPYD Tip Sheet
Irinotecan Tip Sheet
Metoclopramide Tip Sheet
NSAIDs Tip Sheets
Phenytoin-Fosphenytoin Tip Sheets
PPIs Tip Sheets
SSRIs Tip Sheets
Statins Tip Sheets
TCAs Tip Sheet
Thiopurines Tip Sheets
Voriconazole Tip Sheet

Patients who have been genotyped by the Colorado Center for Personalized Medicine (CCPM) Biobank laboratory and consented to receive results may receive results if they are available. For pharmacogenetic results, participants will be notified via UCHealth's MyHealthConnection patient portal.  The date that these results file into the EHR is the date that the sample was initially collected, which may be several years before notification that results are now available.  If you or your patient is having a hard time finding their results, please scroll back several years in the EHR to identify these results. 

No. Patients who have been genotyped through the Colorado Center for Personalized Medicine (CCPM) Biobank laboratory will have results placed directly into the UCHealth EHR.  Patients will be notified of these results through UCHealth's MyHealthConnection patient portal.  CCPM has embedded clinical decision support tools into UCHealth’s EHR to notify clinicians of gene-drug interactions at the time of prescribing.  

For further information, please visit the drug-gene specific resources and tip sheets above. 

An Important Note

The information you receive through this website is not intended to be medical advice.  The information you receive through this website will include genetic test results only.  If you need medical assistance, please seek care at an appropriate facility.  You should contact your doctor about any genetic test results that you receive from the Biobank.  Do not stop using or change any of your medicines before speaking with your doctor.

Colorado Center for Personalized Medicine

University of Colorado Anschutz Medical Campus

CU Anschutz

Anschutz Health Sciences Building

1890 N Revere Ct

Mailstop F563

Aurora, CO 80045


Contact Us
  • (303) 724-9944
  • CCPM-Biobank@ucdenver.edu
Study Title
  • Colorado Center for Personalized Medicine (CCPM) Biobank Research Study
COMIRB#
  • 15-0461 PI: Kristy Crooks, PhD, FACMG: Director, CCPM Biobank
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