Pharmacogenetics & Transplant

Special Exceptions to the Use of Pharmacogenetic Test Results

Pharmacogenetic results should NOT be used for clinical decision-making if the patient has undergone an allogeneic bone marrow transplant or liver transplant.

PGx Exceptions

Pharmacogenetic results obtained from a blood sample in patients who have undergone liver transplantation may not accurately reflect the patient's liver genotype. The donor liver may have an alternate genotype than the patient's (recipient's) blood. This is particularly important since the majority of pharmacogenetics is focused on genetic variants in cytochrome P450 in the liver.

Webpage updated as of: 9/9/24

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Colorado Center for Personalized Medicine

Pharmacogenetics & Transplant

Special Exceptions to the Use of Pharmacogenetic Test Results

Pharmacogenetic results should NOT be used for clinical decision-making if the patient has undergone an allogeneic bone marrow transplant or liver transplant.

Colorado Center for Personalized Medicine

Pharmacogenetics & Transplant

Special Exceptions to the Use of Pharmacogenetic Test Results

Pharmacogenetic results should NOT be used for clinical decision-making if the patient has undergone an allogeneic bone marrow transplant or liver transplant.

Allogeneic Bone Marrow Transplant

Liver Transplant

Colorado Center for Personalized Medicine