Aoto, Jason, Assistant Professor
Ph.D., 2009, Univ. of California, Berkeley
We are interested in dissecting the distinct functions of synaptic cell-adhesion molecules implicated in neuropsychiatric disorders and addiction in the context of disease-relevant brain circuits. Using cutting-edge multidisciplinary techniques, we are able to interrogate these molecules with cell-type and synapse-specific resolution.
Ph.D., 1996, Heinrich-Pette-Institute
Molecular memory mechanisms in cellular signal transduction and neuronal function; CaMKII and Ca2+ signaling.
Ph.D., 1995, Harvard Univ.
Organization of signaling complexes by protein kinase and phosphatase anchoring proteins; mechanisms regulating neuronal second messenger signaling in synaptic plasticity.
Ph.D., 2003, Univ. of Alberta
We study synaptic mechanisms by which neuromodulators like dopamine and acetylcholine are encoded in mesolimbic and nigrostriatal circuits through GPCRs. We study the basic biology of these circuits and the alterations that occur in neurological and psychiatric diseases.
Ph.D., 1974, City Univ. of New York
Neuropharmacology; mechanisms of alcohol tolerance, dependence, and craving; genetic aspects of alcohol dependence and affective disorders; biochemical/molecular biological/genetic analysis of CNS receptors and signal transduction systems.
Ph.D., 1989, Yale Univ.
Computational biology, bioinformatics, gene expression array analysis, natural language processing, biomedical ontologies, machine learning.
Ph.D., 2003, Univ. of Washington
Molecular mechanisms of activity-triggered synaptic remodeling.
Ph.D., 1988, Moscow State Univ.
Epigenetics, phosphoinositide signaling, structural biology, NMR and crystal structures of proteins implicated in cancer, structure based drug design.
Oh, Won Chan, Assistant Professor
Ph.D. 2013, Univ. of California, Davis
We study molecular and cellular mechanisms of activity-dependent synaptic and circuit remodeling primarily through live-imaging approaches using two-photon microscopy and photostimulation in vivo and in brain slices, combined with electrophysiology and molecular genetic manipulations.
Ph.D., 1988, Univ. of Washington
Signaling through calcium channels in neurons.
Ph.D., 2010, University College London
Molecular mechanisms of excitatory and inhibitory synaptic plasticity.
M.D./Ph.D., 1995, Baylor College of Medicine
Mechanisms of synaptic plasticity and impacts of development and epilepsy.
Ph.D., 2006, University of Bordeaux, France
The overall goal of our laboratory is to understand the control of cerebral blood flow by ion channels and calcium signaling in the pericytes, endothelial cells, and smooth muscle cells that constitute the parenchymal microcirculation, and use this information to combat brain diseases with a vascular component.
Ph.D., 2007, Medical University of South Carolina
Basic neuroscience research using neuropharmacology, optogenetics, chemogenetics, and behavior to study the mechanisms of extinction memory and relapse in animal models of addiction.