Patient Education Resources
Clinicians using the UCHealth EHR can use dotphrase: .pgxrosuvastatintopatient
Rosuvastatin Tip Sheet: ABCG2 Poor Function and SLCO1B1 Poor Function
The following information is intended for use by providers who are attempting to prescribe rosuvastatin to patients with certain ABCG2 and SLCO1B1 phenotypes.
For immediate questions, send a secure chat message to Groups: Pharmacogenomics Service in UCHealth's EHR.
References:
- Grundy SM, et al. 2018 Guideline on the management of blood cholesterol: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2019; 73(24):3237-3241.
- Cooper-DeHoff R, et al. The Clinical Pharmacogenetics Implementation Consortium guideline for SLCO1B1, ABCG2, and CYP2C9 and statin-associated musculoskeletal symptoms. Clin Pharmacol Ther. 2022 May;111(5):1007-1021.
Rosuvastatin & ABCG2 Poor Function and SLCO1B1 Poor Function Tip Sheet by Christina L. Aquilante is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Based on a work at https://medschool.cuanschutz.edu/cobiobank/providers/results/pgx/rosuvastatin-tipsheets/tipsheet-c.