Abigail Person, PhD
Professor
/abigail-person----200-x-225.jpg?sfvrsn=187362b9_4 "Abigail Person, PhD")
Department of Physiology and Biophysics
University of Colorado Anschutz
RC1 North Tower, P18-7119
Mail Stop 8307
Aurora, CO 80045
Tel: (303) 724-4514
E-mail: [email protected]
External Website: http://www.personlab.org/
Graduate Program Affiliations:
- Neuroscience Graduate Program
- Bioengineering
- MSTP
- BSP
Shared Content Block:
Physiology & Biophysics Styles -- Borderless table for directories
Abigail Person's laboratory studies the contribution of the cerebellum
to motor control, focusing on circuit mechanisms that support smooth,
precise movement. A central idea in cerebellar physiology is that the
position of the body is monitored via copies of motor commands conveyed
by "corollary discharge pathways". By combining physiology,
optogenetics, anatomical methods, and behavior we address how cerebellar
circuitry makes movements precise. These topics are at the heart of the
role of the cerebellum as a sensorimotor integrator. Disorders of this
circuitry are hypothesized to contribute to some aspects of disorders
such as autism and schizophrenia as well as broad motor disturbances
seen in cerebellar ataxias./courtney-dobrott-(100-x-125).jpg?sfvrsn=cc3848bb_2 "Courtney Dobrott") | Courtney Dobrott Graduate Student |
/kait100x125.jpg "Kaitlyn Letourneau") | Kaitlyn Letourneau Graduate Student |
/img_8625.jpeg "Julia") | Julia Lemak Graduate Student |
/jackson-stocking.jpg?sfvrsn=5b2f2b4_0 "jackson-stocking") | Jackson Stocking Graduate Student |
/abd-el-raheem-nashef-(100-x-125).jpg?sfvrsn=887349bb_2 "Abd El Raheem Nashef") | Abdulraheem (Abed) Nashef Postdoctoral Researcher |
/katrina-nguyen-(100-x-125).jpg?sfvrsn=acee49bb_2 "Katrina Nguyen") | Katrina Nguyen Postdoctoral Researcher |
/michael-spindle-(100-x-125).jpg?sfvrsn=b4094bbb_2 "Michael Spindle") | Michael Spindle Senior Professional Research Assistant |
/group-photos/person-lab-2023.jpg?sfvrsn=43fd0bbb_2 "Person Lab members")
Person AL, Khodakhah K (2016) Recurrent Feedback Loops in Associative Learning. Neuron. Feb 3;89(3):427-30
Houck BD, Person AL (2015) Cerebellar Premotor Output Neurons Collateralize to Innervate the Cerebellar Cortex. J Comp Neurol. Oct 15;523(15):2254-71
Houck BD, Person AL (2014) Cerebellar loops: a review of the nucleocortical pathway. Cerebelum. 13:378-85
Heck DH, De Zeeuw CI, Jaeger D, Khodakhah K, Person AL(2013) The neuronal code(s) of the cerebellum. J Neurosci. 2013 33:17603-9
Person AL, Raman IM. (2012) Synchrony and neural coding in cerebellar circuits. Front Neural Circuits. 6:97
Person AL, Raman IM (2011) Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei. Nature 481: 502-5
Person AL, Raman IM (2010) Deactivation of L-type calcium current by inhibition controls LTP at excitatory synapses in the cerebellar nuclei. Neuron 66: 550-559
Person AL*, Gale SD*, Farries MA, Perkel DJ. (2008) Organization of songbird basal ganglia, including area X. J Comp Neurol 508: 840:66
*equal contribution
Gale SD*,
Person AL*, Perkel DJ. (2008) A novel basal ganglia pathway forms a loop linking a vocal learning circuit with its dopaminergic input. J Comp Neurol 508: 824-39
*equal contribution
Person AL, Perkel DJ (2007) Pallidal neuron activity increases during sensory relay through thalamus in a songbird circuit essential for learning. J Neurosci 27: 8687-98.
Person AL, Perkel DJ (2005) Unitary IPSPs drive precise thalamic spiking in a circuit required for learning. Neuron 46: 129-40.
- Alfred P. Sloan Research Fellow
- Esther A and Joseph Klingenstein Fund Award in the Neurosciences
- Boettcher Investigator: Webb-Waring Biomedical Research Award