Recent Publications | Physiology and Biophysics

High-frequency spike inference with particle Gibbs sampling

High-frequency spike inference with particle Gibbs sampling. Giovanni Diana, Semihcan Sermet, Gerard J Broussard, Samuel S-H Wang, David A DiGregorio, DA eLife (2026-5-27)
DOI: 10.7554/eLife.94723 PMID: 42200510 PMCID: PMC13215672

— David DiGregorio

Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits

Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits. Changjoo Park, Zhen Yang, Abdulraheem Nashef, Jawon Gim, Sangkyu Bahn, Gyu Hyun Kim, Ke Zhang, Laurence Cathala, Sungho Hong, Yoonseok Im, Sang-Hoon Lee, Kisuk Lee, Min-Soo Kim, Don B Arnold, Kea Joo Lee, Jason M Christie, Jinseop S Kim, JS Nature neuroscience (2026-5-14)
PMID: 42135511 DOI: 10.1038/s41593-026-02268-2

— Jason Christie

Timing is everything: myelin and coincidence detection

Timing is everything: myelin and coincidence detection. Kimberly Gagnon, Gustavo Della Flora Nunes, Cristin G Welle, Ethan G Hughes Trends in neurosciences (2026-3)
DOI: 10.1016/j.tins.2026.02.001 PMID: 41771721 PMCID: PMC12959352

— Cristin G Welle

Non-uniform spike count shared variability in the mouse early visual system

Non-uniform spike count shared variability in the mouse early visual system. Jordan L Hickman, Juan Santiago Moreno, Grant Hughes, Eashan Sahai, Nicholas Garcia, Daniel J Denman
PMID: 41830477 DOI: 10.1152/jn.00382.2025

— Daniel J Denman

Machine learning discovers numerous new computational principles supporting elementary motion detection

Machine learning discovers numerous new computational principles supporting elementary motion detection. Nature communications (2026-3-03)
DOI: 10.1038/s41467-026-70288-4 · PMID: 41776191

— Alon Poleg-Polsky

Correlates of head-fixed directional forelimb movements in mouse superior colliculus and substantia nigra pars reticulata

Correlates of head-fixed directional forelimb movements in mouse superior colliculus and substantia nigra pars reticulata. Doykos TK, Yamauchi T, Buteau A, Hanson S, Dudman JT, Felsen G, Stubblefield EA. Neuroscience. 2026 Apr 6;599:65-75.
DOI: 10.1016/j.neuroscience.2026.02.010. Epub 2026 Feb 12. PMID: 41690568.

— Gidon Felsen

Connexin 36-mediated gap junctions contribute to fine odour discrimination and late-phase excitation of mitral cells in the mouse olfactory bulb

Connexin 36-mediated gap junctions contribute to fine odour discrimination and late-phase excitation of mitral cells in the mouse olfactory bulb. Kuruppath, P; Jones, ST; Pouille, F; Ramirez-Gordillo, D; Restrepo, D; Schoppa, NE
DOI: 10.1113/JP289975 PMCID: PMC12700349

—Nathan Schoppa

Spatial hearing and temporal processing ability of the Mongolian gerbil (Meriones unguiculatus) measured using prepulse inhibition of acoustic startle

Spatial hearing and temporal processing ability of the Mongolian gerbil (Meriones unguiculatus) measured using prepulse inhibition of acoustic startle. Sergison, MD; Poleg, S; Greene, NT; Klug, A; Tollin, DJ
DOI: 10.1016/j.heares.2025.109507

—Daniel Tollin

A complete spatial map of mouse retinal ganglion cells reveals density and gene expression specializations

A complete spatial map of mouse retinal ganglion cells reveals density and gene expression specializations. Budoff, SA; Poleg-Polsky, A
DOI: 10.1073/pnas.2515449122

—Alon Poleg-Polsky

Distinct dendritic integration strategies control dynamics of inhibition in the neocortex

Distinct dendritic integration strategies control dynamics of inhibition in the neocortex. Annunziato Morabito, Yann Zerlaut, Dhanasak Dhanasobhon, Emmanuelle Berthaux, Cibele Martins Pinho, Alexandra Tzilivaki, Gael Moneron, Laurence Cathala, Panayiota Poirazi, Alberto Bacci, David A DiGregorio, Joana Lourenço, Nelson Rebola
DOI: 10.1016/j.neuron.2025.05.029 PMID: 40592329

— David DiGregorio

Developmental auditory deprivation in one ear impairs brainstem binaural processing and reduces spatial hearing acuity

Developmental auditory deprivation in one ear impairs brainstem binaural processing and reduces spatial hearing acuity. Kelsey L Anbuhl, Alexander T Ferber, Andrew D Brown, Victor Benichoux, Nathaniel T Greene, Daniel J Tollin
DOI: 10.1371/journal.pbio.3003337 PMID: 40911627 PMCID: PMC12412938

— Daniel Tollin

Structural basis of fast N-type inactivation in Kv channels

Structural basis of fast N-type inactivation in Kv channels. Xiao-Feng Tan, Ana I Fernández-Mariño, Yan Li, Tsg-Hui Chang, Kenton J Swartz
DOI: 10.1038/s41586-025-09339-7 PMID: 40770100 PMCID: PMC12460158

— Ana I Fernández-Mariño

cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs

Camp and Voltage Modulate Rat Auditory Mechanotransduction by Decreasing the Stiffness of Gating Springs. AA Mecca, GA Caprara, AW Peng Proceedings of the National Academy of Sciences of the United States of America (2022-07-19)
DOI: 10.1073/pnas.2107567119 · PMID: 35858439 · PMCID: PMC9335186

— Anthony Peng

Visual pursuit: Coordinated eye and head movements guide navigation over fixation

Visual Pursuit: Coordinated Eye and Head Movements Guide Navigation over Fixation. B Scholl Current Biology : CB (2025-03-10)
DOI: 10.1016/j.cub.2025.01.031 · PMID: 40068615

— Benjamin Scholl

Zebrafish as a Model System for the Study of Severe CaV2.1 (α1A) Channelopathies

Zebrafish as a Model System for the Study of Severe CaV2.1 (α1A) Channelopathies. S Tyagi, AB Ribera, RA Bannister Frontiers in Molecular Neuroscience (2020-02-07)
DOI: 10.3389/fnmol.2019.00329 · PMID: 32116539 · PMCID: PMC7018710

— Angie Ribera

Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

Vagus Nerve Stimulation Drives Selective Circuit Modulation Through Cholinergic Reinforcement. S Bowles, J Hickman, X Peng, WR Williamson, R Huang, K Washington, D Donegan, CG Welle Neuron (2022-07-19)
DOI: 10.1016/j.neuron.2022.06.017 · PMID: 35858623 · PMCID: PMC10212211

— Cristin Welle

Ultrastructural Contributions to Extrasynaptic Glutamatergic Signaling in Olfactory Bulb Glomeruli

Ultrastructural Contributions to Extrasynaptic Glutamatergic Signaling in Olfactory Bulb Glomeruli. JN Bourne, NE Schoppa The Journal of Comparative Neurology (2025-03)
DOI: 10.1002/cne.70034 · PMID: 40090882 · PMCID: PMC11925490

— Nathan Schoppa

Using Stapes Velocity to Estimate the Efficacy of Mechanical Stimulation of the Round Window With an Active Middle Ear Implant

Using Stapes Velocity to Estimate the Efficacy of Mechanical Stimulation of the Round Window with an Active Middle Ear Implant. DJ Tollin, K Koka, J Peacock Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology (2023-03-24)
DOI: 10.1097/mao.0000000000003859 · PMID: 36962010 · PMCID: PMC10175173

— Daniel Tollin

The funny current If is essential for the fight-or-flight response in cardiac pacemaker cells

The Funny Current If Is Essential for the Fight-or-flight Response in Cardiac Pacemaker Cells. CH Peters, C Rickert, S Morotti, E Grandi, KA Aronow, KG Beam, C Proenza The Journal of General Physiology (2022-10-28)
DOI: 10.1085/jgp.202213193 · PMID: 36305844 · PMCID: PMC9812006

— Kurt Beam

— Catherine Proenza

The distal C terminus of the dihydropyridine receptor β1a subunit is essential for tetrad formation in skeletal muscle

The Distal C Terminus of the Dihydropyridine Receptor β1a subunit is essential for tetrad formation in skeletal muscle. A Dayal, S Perni, C Franzini-Armstrong, KG Beam, M Grabner Proceedings of the National Academy of Sciences of the United States of America (2022-05-04) DOI: 10.1073/pnas.2201136119 · PMID: 35507876 · PMCID: PMC9171810