Publications

Selected Publications

The Akt-mTOR Pathway Drives Myelin Sheath Growth by Regulating Cap-Dependent Translation

Karlie Fedder-Semmes, Bruce Appel

September 2, 2021

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Temporal single-cell transcriptomes of zebrafish spinal cord pMN progenitors reveal distinct neuronal and glial progenitor populations.

Kayt Scott, Rebecca O'Rourke, Caitlin C. Winkler, Christina A. Kearns, Bruce Appel

July 23, 2021

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Microglia phagocytose myelin sheaths to modify developmental myelination

Alexandria N. Hughes, Bruce Appel
July 6, 2020
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Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating Shh signaling response

Kayt Scott, Rebecca O’Rourke, Austin Gillen, Bruce Appel
March 27, 2020
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The RNA binding protein fragile X mental retardation protein promotes myelin sheath growth

Caleb A. Doll, Katie M. Yergert, Bruce H. Appel
October 12, 2019
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Oligodendrocytes express synaptic proteins that modulate myelin sheath formation

Alexandria N. Hughes, Bruce Appel
September 11, 2019
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Developmental myelination is modified by microglial pruning 

Alexandria N. Hughes, Bruce Appel
June 3, 2019
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Neuronal Activity Enhances mRNA Localization to Myelin Sheaths During Development 

Katie M. Yergert, Jacob H. Hines, Bruce Appel
May 30, 2019
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Sequential specification of oligodendrocyte lineage cells by distinct levels of Hedgehog and Notch signaling 

Andrew M. Ravanellia, Christina A. Kearns, Rani K. Powers, Yuying Wanga, acob H. Hinesa, Maranda J. Donaldson, Bruce Appel
December 15, 2018
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Synaptic proteins expressed by oligodendrocytes mediate CNS myelination 

Alexandria N. Hughes, Bruce Appel
September 6, 2018
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Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling 

Emily S. Mathews and Bruce Appel
July 20, 2016
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miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling

Laura I. Hudish, Domenico F. Galati, Andrew M. Ravanelli, Chad G. Pearson, Peng Huang and Bruce Appel
May 5, 2016
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Motor neurons and oligodendrocytes arise from distinct cell lineages by progenitor recruitment 

Andrew M. Ravanelli and Bruce Appel
November 18, 2015
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Fbxw7 Limits Myelination by Inhibiting mTOR Signaling 

Christina A. Kearns, Andrew M. Ravanelli, Kirsten Cooper and Bruce Appel
November 4, 2015
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Neuronal activity biases axon selection for myelination in vivo 

Jacob H. Hines, Andrew M. Ravanelli, Rani Schwindt, Ethan K. Scott, and Bruce Appel
April 6, 2015
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Mutation of 3-Hydroxy-3-Methylglutaryl CoA Synthase I Reveals Requirements for Isoprenoid and Cholesterol Synthesis in Oligodendrocyte Migration Arrest, Axon Wrapping, and Myelin Gene Expression 

Emily S. Mathews, David J. Mawdsley, Macie Walker, Jacob H. Hines, Marina Pozzoli, and Bruce Appel
February 26, 2014
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miR-219 Regulates Neural Precursor Differentiation by Direct Inhibition of Apical Par Polarity Proteins 

Laura I. Hudish, Alex J. Blasky, and Bruce Appel
November 25, 2013
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CNS-derived glia ensheath peripheral nerves and mediate motor root development 

Sarah Kucenas, Norio Takada, Hae-Chul Park, Elvin Woodruff, Kendal Broadie, and Bruce Appel
January 6, 2008
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In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development 

Brandon B Kirby, Norio Takada, Andrew J Latimer, Jimann Shin, Thomas J Carney, Robert N Kelsh & Bruce Appel
November 12, 2006
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