TPMT Intermediate or Normal Metabolizers
+ NUDT15 Intermediate or Normal Metabolizers
Thiopurines Tip Sheets
The following information is intended for use by providers who are attempting to prescribe thiopurines (azathioprine, 6-mercaptopurine, or thioguanine) to patients with certain TPMT and NUDT15 genetic variants.
TPMT Intermediate or Normal Metabolizers
+ NUDT15 Poor Metabolizers
TPMT Poor Metabolizers
+ any NUDT15 Metabolizer Phenotype