More Information for Your Patients
Click Here
Sacituzumab govitecan-hziy Tip Sheet
The following information is intended for use by providers who are attempting to prescribe Sacituzumab govitecan-hziy to patients with certain UGT1A1 genetic variants.
For immediate questions, send a secure chat message to Groups: "Pharmacogenomics Service" in UCHealth's EHR.
References:
- Trodelvy Prescribing Information: https://www.gilead.com/-/media/files/pdfs/medicines/oncology/trodelvy/trodelvy_pi.pdf
- Dello Russo et al. UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta-Analysis. Clin Pharmacol Ther. 2026 Jan;119:63-73. https://pmc.ncbi.nlm.nih.gov/articles/PMC12746514/
Sacituzumab and UGT1A1 Tip Sheet by Christina L. Aquilante is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Webpage updated as of: 1/29/26